Dose reduction of asparaginase under pharmacokinetic and pharmacodynamic control during induction therapy in children with acute lymphoblastic leukaemia

British Journal of Haematology

Volumn 96, Issue 4, 1997, Pages 675-681

  Ahlke, Elvira ^a,b   Nowak GÖTTL, Ulrike ^a   Schulze Westhoff, Petra ^a   Werber, Gisela ^a   Börste, Hedwig ^a   Würthwein, Gudrun ^a   Jürgens, Herbert ^a   Boos, Joachim ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

asparaginase; childhood leukaemia; coagulation parameters; dose reduction; pharmacokinetics

Indexed keywords

ASPARAGINASE; ASPARAGINASE MEDAC; DAUNORUBICIN; METHOTREXATE; PREDNISONE; UNCLASSIFIED DRUG; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DOSE; FEMALE; HUMAN; INFANT; INTRATHECAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL;

EID: 0031049365     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.d01-2089.x     Document Type: Article

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