Placental growth factor in the cerebrospinal fluid of women with preeclampsia

International Journal of Gynecology and Obstetrics

Volumn 92, Issue 1, 2006, Pages 32-37

  Foyouzi, N ^a   Norwitz, E R ^a   Tsen, L C ^b   Buhimschi, C S ^a   Buhimschi, I A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Angiogenic factors; Cerebrospinal fluid; PlGF; Preeclampsia; sFlt 1; VEGF

Indexed keywords

PLACENTAL GROWTH FACTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1;

ADULT; ANGIOGENESIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL COUNT; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID ANALYSIS; CEREBROSPINAL FLUID CYTOLOGY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN CELL; HYPERTENSION ENCEPHALOPATHY; IMMUNOASSAY; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN DETERMINATION;

EID: 28844457647     PISSN: 00207292     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijgo.2005.09.004     Document Type: Article

References (25)

1. American College of Obstetricians and Gynecologists Diagnosis and management of preeclampsia and eclampsia Practice bulletin vol. 33 2002 ACOG Washington, DC
2. C.J. Berg, H.K. Atrash, L.M. Koonin, and M. Tucker Pregnancy-related mortality in the United States, 1987-1990 Obstet Gynecol 88 1996 161 167
3. A.P. MacKay, C.J. Berg, and H.K. Atrash Pregnancy-related mortality from preeclampsia and eclampsia Obstet Gynecol 97 2001 533 538
4. K.A. Douglas, and C.W.G. Redman Eclampsia in the United Kingdom Br Med J 309 1994 1395 1400
5. S.E. Maynard, J.Y. Min, J. Merchan, K.H. Lim, J. Li, and S. Mondal Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia J Clin Invest 111 2003 649 658
6. S. Ahmad, and A. Ahmed Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsia Circ Res 95 2004 884 891
7. R.J. Levine, S.E. Maynard, C. Qian, K.H. Lim, L.J. England, and K.F. Yu Circulating angiogenic factors and the risk of preeclampsia N Engl J Med 350 2004 672 683
8. G.C. McKeeman, J.E. Ardill, C.M. Caldwell, A.J. Hunter, and N. McClure Soluble vascular endothelial growth factor receptor-1 (sFlt-1) is increased throughout gestation in patients who have preeclampsia Am J Obstet Gynecol 191 2004 1240 1246
9. R.L. Kendall, and K.A. Thomas Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor Proc Natl Acad Sci U S A 90 1993 10705 10709
10. N. Ferrara, H.-P. Gerber, and J. LeCouter The biology of VEGF and its receptors Nat Med 9 2003 669 676
11. E. Tischer, R. Mitchell, T. Hartman, M. Silva, D. Gospodarowicz, and J.C. Fiddes The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing J Biol Chem 266 1991 11947 11954
12. K.A. Houck, D.W. Leung, A.M. Rowland, J. Winer, and N. Ferrara Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms J Biol Chem 267 1992 26031 26037
13. D. Maglione, V. Guerriero, G. Viglietto, P. Delli-Bovi, and M.G. Persico Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor Proc Natl Acad Sci U S A 88 1991 9267 9271
14. S. Hauser, and H.A. Weich A heparin-binding form of placenta growth factor (PlGF-2) is expressed in human umbilical vein endothelial cells and in placenta Growth Factors 9 1993 259 268
15. C.S. Buhimschi, E.R. Norwitz, E. Funai, S. Richman, S. Guller, and C.J. Lockwood Urinary angiogenic factors cluster hypertensive disorders and identify women with severe preeclampsia Am J Obstet Gynecol 192 2005 734 741
16. R.J. Levine, R. Thadhani, C. Qian, C. Lam, K.H. Lim, and K.F. Yu Urinary placental growth factor and risk of preeclampsia JAMA 293 2005 77 85
17. N. Ferrara, K. Houck, L. Jakeman, and D.W. Leung Molecular and biological properties of the vascular endothelial growth factor family of proteins Endocr Rev 13 1992 18 32
18. E. Berra, G. Pages, and J. Pouyssegur MAP kinases and hypoxia in the control of VEGF expression Cancer Metastasis Rev 19 2000 139 145
19. H. Li, B. Gu, Y. Zhang, D.F. Lewis, and Y. Wang Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta Placenta 26 2005 210 217
20. M. Wolf, C.A. Hubel, C. Lam, M. Sampson, J.L. Ecker, and R.B. Ness Preeclampsia and future cardiovascular disease: potential role of altered angiogenesis and insulin resistance J Clin Endocrinol Metab 89 2004 6239 6243
21. R.B. Schwartz, K.M. Jones, P. Kalina, R.L. Bajakian, M.T. Mantello, and B. Garada Hypertensive encephalopathy: findings on CT, MR imaging, and SPECT imaging in 14 cases Am J Radiol 159 1992 379 383
22. K.M. Apollon, J.N. Robinson, R.B. Schwartz, and E.R. Norwitz Cortical blindness in severe preeclampsia: computed tomography, magnetic resonance imaging and single-photon emission computed tomography findings Obstet Gynecol 95 2000 1017 1019
23. S. Nag Pathophysiology of the blood-brain barrier breakdown Methods Mol Med 89 2003 97 119
24. I.A. Buhimschi, L.C. Tsen, J.-S. Park, N. Foyouzi, P. Fitzpatrick, D. Dorfman, and C.S. Buhimschi Proteomic profiling of cerebrospinal fluid (CSF) in patients with severe preeclampsia suggests subclinical micro-hemorrhage with functional consequences 2005 Society for Maternal-Fetal Medicine Reno, NV [Abstract]
25. E.R. Norwitz, L.C. Tsen, J.S. Park, P. Fitzpatrick, D. Dorfman, and C.S. Buhimschi Discriminatory proteomic biomarker analysis identifies free hemoglobin in the cerebrospinal fluid of women with severe preeclampsia Am J Obstet Gynecol Am J Obstet Gynecol 193 2005 957 964