Drug-excipient compatibility testing using a high-throughput approach and statistical design

Pharmaceutical Development and Technology

Volumn 10, Issue 4, 2005, Pages 499-505

  Wyttenbach, Nicole ^a   Birringer, Christian ^a   Alsenz, Jochem ^a   Kuentz, Martin ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Categorical statistical design; Drug degradation; Drug excipient compatibility test; Miniaturized

Indexed keywords

ACETYLSALICYLIC ACID; CALCIUM PHOSPHATE DIBASIC; EXCIPIENT; FLUOXETINE; HYDROXYPROPYLMETHYLCELLULOSE; LACTOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; POVIDONE; STARCH GLYCOLATE SODIUM;

ARTICLE; DRUG DEGRADATION; DRUG STABILITY; EXCIPIENT COMPATIBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; HUMIDITY; MICROTITER PLATE ASSAY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TEMPERATURE;

ASPIRIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATA INTERPRETATION, STATISTICAL; DRUG COMPOUNDING; DRUG INCOMPATIBILITY; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; FLUOXETINE; HEAT; HUMIDITY; PHARMACEUTICAL PREPARATIONS; TIME FACTORS;

EID: 28844453310     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450500299875     Document Type: Article

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