The ruthenium-based nitric oxide scavenger, AMD6221, augments cardiovascular responsiveness to noradrenaline in rats with streptozotocin- induced diabetes

European Journal of Pharmacology

Volumn 528, Issue 1-3, 2005, Pages 132-136

  Hutchings, Simon R ^a   Song, Dongzhe ^a   Fricker, Simon P ^b   Pang, Catherine C Y ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b GENZYME CORPORATION   (United States)

Author keywords

Cardiovascular dysfunction; Nitric oxide scavenger; Oxidative stress; Streptozotocin induced diabetes

Indexed keywords

AMD 6221; NITRIC OXIDE; NORADRENALIN; RUTHENIUM [HYDROGEN(DIETHYLENETRINITRILO)PENTAACETATO]CHLORIDE; RUTHENIUM DERIVATIVE; STREPTOZOCIN; THIOBARBITURIC ACID; UNCLASSIFIED DRUG;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG RESPONSE; HEART FUNCTION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; SYSTOLIC BLOOD PRESSURE;

ANIMALS; BLOOD PRESSURE; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; FREE RADICAL SCAVENGERS; HEART RATE; MALE; MYOCARDIAL CONTRACTION; NITRIC OXIDE; NOREPINEPHRINE; ORGANOMETALLIC COMPOUNDS; PENTETIC ACID; RATS; RATS, WISTAR; STREPTOZOCIN; VASCULAR RESISTANCE; VASOCONSTRICTOR AGENTS; VENTRICULAR FUNCTION, LEFT;

EID: 28844440472     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.10.039     Document Type: Article

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