A ruthenium (III) polyaminocarboxylate complex, a novel nitric oxide scavenger, enhances graft survival and decreases nitrosylated heme protein in models of acute and delayed cardiac transplant rejection

Journal of Cardiovascular Pharmacology

Volumn 39, Issue 3, 2002, Pages 441-448

  Pieper, Galen M ^a   Roza, Allan M ^a   Adams, Mark B ^a   Hilton, Gail ^a   Johnson, Mary ^a   Felix, Christopher C ^a   Kampalath, Bal ^a   Darkes, Marilyn ^a   Wanggui, Yangsheng ^a   Cameron, Beth ^a   Fricker, Simon P ^a  

^a FROEDTERT MEMORIAL LUTHERAN HOSPITAL   (United States)

Author keywords

Electron paramagnetic resonance spectroscopy; Myocardial transplantation; Nitric oxide; Nitrosylation; Ruthenium; Transplant rejection

Indexed keywords

AMD 3689; AMD 6221; CYCLOSPORIN; DRUG METABOLITE; HEMOPROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; RUTHENIUM COMPLEX; RUTHENIUM POLYAMINOCARBOXYLATE; SCAVENGER; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG MECHANISM; ELECTRON SPIN RESONANCE; GENE LOCUS; GRAFT REJECTION; GRAFT SURVIVAL; HEART GRAFT; HEART PROTECTION; HEART TRANSPLANTATION; HISTOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; OXIDATIVE STRESS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MODIFICATION; PROTEIN PROCESSING; RAT; XENOTRANSPLANTATION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOSPORINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICAL SCAVENGERS; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HEMEPROTEINS; IMMUNOSUPPRESSIVE AGENTS; NITRATES; NITRIC OXIDE; NITRITES; ORGANOMETALLIC COMPOUNDS; PENTETIC ACID; RATS; RATS, INBRED LEW; RATS, INBRED WF; RUTHENIUM;

EID: 0036179863     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200203000-00016     Document Type: Article

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