Novel isosorbide-based substrates for human butyrylcholinesterase

Chemico-Biological Interactions

Volumn 157-158, Issue , 2005, Pages 317-319

  Gilmer, J F ^a   Lally, M N ^a   Gardiner, P ^a   Dillon, G ^a   Gaynor, J M ^b   Reidy, S ^b  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b Athletic Rehabilitation Therapy Ireland   (Ireland)

Author keywords

Butyrylcholinesterase; Human plasma; Isosorbide esters; Substrate

Indexed keywords

CHOLINESTERASE; ESTER; ISOSORBIDE; SUGAR;

CATALYSIS; CONFERENCE PAPER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROLYSIS; INCUBATION TIME; MEASUREMENT; PLASMA; SYNTHESIS;

BUTYRYLCHOLINESTERASE; ESTERS; GLYCOLATES; HUMANS; ISOSORBIDE; MOLECULAR STRUCTURE; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 28744443583     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2005.10.095     Document Type: Conference Paper

References (3)

1. J.F. Gilmer, L.M. Moriarty, M.N. Lally, and J.M. Clancy Isosorbide-based aspirin prodrugs. Part II. Hydrolysis kinetics of isosorbide diaspirinate. Eur. J. Pharm. Sci. 16 2002 297 304
2. J.F. Gilmer, L.M. Moriarty, D.F. McCafferty, and J.M. Clancy Synthesis, hydrolysis kinetics and antiplatelet effects of isosorbide mononitrate derivatives of aspirin Eur. J. Pharm. Sci. 14 3 2001 221 227
3. M. Harel, J.L. Sussman, E. Krejci, S. Bon, P. Chanal, J. Massoulie, and I. Silman Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis Proc. Natl. Acad. Sci. U.S.A. 89 1992 10827 10831