A count-rate model for PET scanners using pixelated Anger-logic detectors with different scintillators

Physics in Medicine and Biology

Volumn 50, Issue 23, 2005, Pages 5697-5715

  Surti, S ^a   Karp, J S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SIMULATION; GADOLINIUM COMPOUNDS; OPTICAL RESOLVING POWER; SCANNING; SIGNAL PROCESSING; SODIUM COMPOUNDS;

ENERGY RESOLUTION; HIGH COUNT-RATE SIMULATION (HCRSIM);

POSITRON EMISSION TOMOGRAPHY;

BROMINE DERIVATIVE; GADOLINIUM ORTHOSILICATE; LANTHANUM BROMIDE; SILICATE; SODIUM IODIDE; UNCLASSIFIED DRUG;

ARTICLE; DEVICE; ENERGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SCINTILLATION; SIMULATION; STANDARDIZATION; TIME; WHOLE BODY SCANNER;

BROMIDES; COMPUTER SIMULATION; GAMMA CAMERAS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LANTHANUM; PHANTOMS, IMAGING; POSITRON-EMISSION TOMOGRAPHY; SCATTERING, RADIATION; SCINTILLATION COUNTING; SENSITIVITY AND SPECIFICITY; SIGNAL PROCESSING, COMPUTER-ASSISTED; SODIUM IODIDE; TIME FACTORS; WHOLE-BODY COUNTING;

EID: 28644442958     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/50/23/020     Document Type: Article

References (33)

1. Adam L-E, Bellemann M E, Brix G and Lorenz W J 1996 Monte Carlo-based analysis of PET scatter components J. Nucl. Med. 37 2024-9
2. Adam L-E, Karp J S and Brix G 1999 Investigation of scattered radiation in 3D whole-body positron emission tomography using Monte Carlo simulations Phys. Med. Biol. 44 2879-95
3. Burnham C, Bradshaw J, Kaufman D, Chesler D and Brownell G 1983 A positron tomograph employing a one dimension BGO scintillation camera IEEE Trans. Nucl. Sci. 30 661-4
4. Burnham C, Kaufman D, Chesler D, Stearns C, Wolfson D and Brownell G 1988 Cylindrical PET detector design IEEE Trans. Nucl. Sci. 35 675-9
5. Eriksson L, Weinhard K and Dahlbom M 1994 A simple data loss model for positron camera systems IEEE Trans. Nucl. Sci. 41 1566-70
6. 3 3D PET scanners: a Monte-Carlo study Presented at the Society of Nuclear Medicine 52nd Annual Meeting J. Nucl. Med. 46 168P
7. Karp J and Muehllehner G 1985 Performance of a position sensitive scintillation detector Phys. Med. Biol. 30 643-55
8. Karp J, Muehllehner G, Beerbohm D and Mankoff D 1986 Event localization in a continuous scintillation detector using digital processing IEEE Trans. Nucl. Sci. 33 550-5
9. Karp J S, Surti S, Freifelder R, Daube-Witherspoon M E, Cardi C, Adam L-E and Muehllehner G 2003 Performance of a GSO PET camera J. Nucl. Med. 44 1340-9
10. Knoll G F 1989 Radiation Detection and Measurement (New York: Wiley)
11. Kuhn A, Surti S, Karp J, Raby P, Shah K, Perkins A and Muehllehner G 2004 Design of a lanthanum bromide detector for TOF PET IEEE Trans. Nucl. Sci. 51 2550-7
12. Manjeshwar R and Jansen F 2005 The impact of time-of-flight on contrast-to-noise ratio is a function of phantom size: a simulation study Presented at the Society of Nuclear Medicine 52nd Annual Meeting J. Nucl. Med. 46 169P
13. Mankoff D A, Muehllehner G and Karp J S 1989 The high count rate performance of a two-dimensionally position-sensitive detector for positron emission tomography Phys. Med. Biol. 34 437-56
14. Moisan C, Rogers J and Douglas J 1997 A count rate model for PET and its application to an LSO HR plus scanner IEEE Trans. Nucl. Sci. 44 1219-24
15. Moses W and Derenzo S 1999 Prospects for time-of-flight PET using LSO scintillator IEEE Trans. Nucl. Sci. 46 474-8
16. Moszyński M, Kapusta M, Wolski D, Szawlowski M and Klamra W 1998 Energy resolution of scintillation detectors: readout with large area avalanche photodiodes and photomultipliers IEEE Trans. Nucl. Sci. 45 472-7
17. Muehllehner G and Karp J 1986 A positron camera using position-sensitive detectors: PENN-PET J. Nucl. Med. 27 90-8
18. Nelson W R, Hirayama H and Rogers D W O 1985 The EGS4 code system SLAC-Report-265 (Stanford: Stanford University)
19. NEMA 1994 NEMA Standards Publication NU 2-1994 (Washington, DC: NEMA)
20. Perkins A E, Muehllehner G, Surti S and Karp J S 2003 Performance measurements of a pixelated NaI(Tl) PET scanner IEEE Trans. Nucl. Sci. 50 373-7
21. Sorenson J A and Phelps M E 1987 Physics in Nuclear Medicine (Philadelphia, PA: Saunders)
22. Surti S 2000 A model of scintillation detector performance for positron emission tomography PhD Thesis University of Pennsylvania
23. Surti S, Karp J S and Freifelder R 2001 Slotted surface treatment of position-sensitive NaI(Tl) detectors to improve detector performance IEEE Trans. Nucl. Sci. 48 2418-23
24. Surti S, Karp J S, Freifelder R and Liu F 2000 Optimizing the performance of a PET detector using discrete GSO crystals on a continuous lightguide IEEE Trans. Nucl. Sci. 47 1030-6
25. Surti S, Karp J S and Muehllehner G 2003a Evaluation of pixelated NaI(Tl) detectors for PET IEEE Trans. Nucl. Sci. 50 24-31
26. 3 based whole-body 3D PET scanners: a Monte Carlo evaluation Phys. Med. Biol. 49 4593-610
27. Surti S, Karp J S, Muehllehner G and Raby P S 2003b Investigation of lanthanum scintillators for 3D PET IEEE Trans. Nucl. Sci. 50 348-54
28. Surti S, Karp J S, Perkins A E, Cardi C A, Daube-Witherspoon M E, Kuhn A and Muehllehner G 2005a Imaging performance of A-PET: a small animal PET camera IEEE Trans. Med. Imaging 24 844-52
29. Surti S, Karp J, Perkins A, Freifelder R and Muehllehner G 2003c Design evaluation of A-PET: a high sensitivity animal PET camera IEEE Trans. Nucl. Sci. 50 1357-63
30. Surti S, Karp J, Popescu L, Daube-Witherspoon M and Werner M 2004b Investigation of image quality and NEC in a TOF capable PET scanner IEEE MIC Conference Record ed J Seibert (IEEE NPSS, IEEE) pp M10-276
31. Surti S, Karp J, Popescu L, Daube-Witherspoon M and Werner M 2005b Image quality improvement in TOF-capable fully-3D PET scanners Presented at the Society of Nuclear Medicine 52nd Annual Meeting J. Nucl. Med. 46 166P
32. van Eijk C W E 2002 Inorganic scintillators in medical imaging Phys. Med. Biol. 47 R85-R106
33. Wear J, Karp J, Freifelder R, Mankoff D and Muehllehner G 1998 A model of the high count rate performance of NaI(Tl)-based PET detectors IEEE Trans. Nucl. Sci. 45 1231-7