Inherited occipital hypoplasia/syringomyelia in the cavalier king charles spaniel: Experiences in setting up a worldwide DNA collection

Journal of Heredity

Volumn 96, Issue 7, 2005, Pages 745-749

  Rusbridge, Clare ^a   Knowler, Penny ^a   Rouleau, Guy A ^b   Minassian, Berge A ^c   Rothuizen, Jan ^d  

^a Stone Lion Veterinary Centre   (United Kingdom)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; DATA BASE; DOG; DOG DISEASE; GENETIC TRAIT; GENOTYPE; HYPOPLASIA; NONHUMAN; OCCIPITAL CORTEX; PHENOTYPE; PRIORITY JOURNAL; SYRINGOMYELIA;

ANIMALS; ARNOLD-CHIARI MALFORMATION; BREEDING; DATABASES, GENETIC; DATABASES, NUCLEIC ACID; DOG DISEASES; DOGS; FEMALE; MAGNETIC RESONANCE IMAGING; MALE; OCCIPITAL BONE; PATIENT SELECTION; QUESTIONNAIRES; SCOLIOSIS; SYRINGOMYELIA;

CANIS FAMILIARIS;

EID: 28644435322     PISSN: 00221503     EISSN: 14657333     Source Type: Journal    
DOI: 10.1093/jhered/esi074     Document Type: Article

References (11)

1. Catala M, 1999. Neuroembryological consideration on the so-called malformative syringomyelia. Neurochirurgie 45(Suppl 1):9-22.
2. Coria F, Quintana F, Rebollo M, Combarros O, and Berciano J, 1983. Occipital dysplasia and Chiari type I deformity in a family. Clinical and radiological study of three generations. J Neurol Sci 62:147-58.
3. McLain K, Schreiner C, Yager KL, Stock JL, and Potter SS, 1992. Ectopic expression of Hox-2.3 induces craniofacial and skeletal malformations in transgenic mice. Mech Devel 39:3-16.
4. Meadows J, Kraut M, Guarnieri M, Haroun RI, and Carson BS, 2000. Asymptomatic Chiari Type 1 malformations identified on magnetic resonance imaging. J Neurosurg 92:920-926.
5. Rasmussen AM, 2005. Understanding line breeding. Available online at www.cavaliers.co.uk; accessed January 2005.
6. Rusbridge C and Knowler SP, 2003. Hereditary aspects of occipital bone hypoplasia and syringomyelia (Chiari type I malformation) in cavalier King Charles spaniels. Vet Record 153:107-112.
7. Rusbridge C and Knowler SP, 2004. Inheritance of Occipital Bone Hypoplasia (Chiari type I malformation) in Cavalier King Charles spaniels. J Vet Int Med 18:673-678.
8. Rusbridge C, MacSweeny JE, Davies JV, Chandler KE, Fitzmaurice SN, Dennis R, Cappello R, and Wheeler SJ, 2000. Syringomyelia in cavalier King Charles spaniels. J Am Animal Hosp Assoc 36:34-41.
9. Speer MC, George TM, Enterline DS, Amy Franklin A, Wolpert CM, and Milhorat TH, 2000. A genetic hypothesis for Chiari I malformation with or without syringomyelia. Neurosurg Focus 8:1-4.
10. Wilting J, Ebensperger C, Muller TS, Koseki H, Wallin J, and Christ B, 1995. Pax-1 in the development of the cervico-occipital transitional zone. Surg Neurol 192:221-227.
11. Zakeri A, Glasauer FE, and Egnatchik JG, 1995. Familial syringohydromyelia: case report and review of the literature. Anat Embryol 44: 48-53.