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Volumn 19, Issue 12, 2005, Pages 2166-2176

Human myeloma cells express the bone regulating gene Runx2/Cbfa1 and produce osteopontin that is involved in angiogenesis in multiple myeloma patients

Author keywords

Angiogenesis; Bone marrow; Multiple myeloma; Osteopontin

Indexed keywords

GROWTH FACTOR; INTERLEUKIN 6; OSTEOPONTIN; SMALL INTERFERING RNA; SOMATOMEDIN C; SYNDECAN 1; TRANSCRIPTION FACTOR RUNX2;

EID: 28544451084     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2403976     Document Type: Article
Times cited : (69)

References (38)
  • 1
    • 0033134764 scopus 로고    scopus 로고
    • Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma
    • Vacca A, Ribatti D, Presta M, Minischetti M, Iurlaro M, Ria R et al. Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. Blood 1999; 93: 3064-3073.
    • (1999) Blood , vol.93 , pp. 3064-3073
    • Vacca, A.1    Ribatti, D.2    Presta, M.3    Minischetti, M.4    Iurlaro, M.5    Ria, R.6
  • 3
    • 0035207952 scopus 로고    scopus 로고
    • Increased bone marrow microvessel density in newly diagnosed multiple myeloma carries a poor prognosis
    • Munshi NC, Wilson C. Increased bone marrow microvessel density in newly diagnosed multiple myeloma carries a poor prognosis. Semin Oncol 2001; 28: 565-569.
    • (2001) Semin. Oncol. , vol.28 , pp. 565-569
    • Munshi, N.C.1    Wilson, C.2
  • 5
    • 0038446643 scopus 로고    scopus 로고
    • Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma
    • Bisping G, Leo R, Wenning D, Dankbar B, Padro T, Kropff M et al. Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma. Blood 2003; 101: 2775-2783.
    • (2003) Blood , vol.101 , pp. 2775-2783
    • Bisping, G.1    Leo, R.2    Wenning, D.3    Dankbar, B.4    Padro, T.5    Kropff, M.6
  • 6
    • 0037480835 scopus 로고    scopus 로고
    • Pro-angiogenetic properties of human myeloma cells: Production of angiopoietin-1 and its potential relationship with myeloma-induced angiogenesis
    • Giuliani N, Colla S, Lazzaretti M, Sala R, Roti G, Mancini C et al. Pro-angiogenetic properties of human myeloma cells: Production of angiopoietin-1 and its potential relationship with myeloma-induced angiogenesis. Blood 2003; 102: 638-645.
    • (2003) Blood , vol.102 , pp. 638-645
    • Giuliani, N.1    Colla, S.2    Lazzaretti, M.3    Sala, R.4    Roti, G.5    Mancini, C.6
  • 8
    • 7844235808 scopus 로고    scopus 로고
    • Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues
    • Sato M, Morii E, Komori T, Sato M, Morii E, Komori T et al. Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/ CBFA1 and ETS1 in the skeletal tissues. Oncogene 1998; 17: 1517-1525.
    • (1998) Oncogene , vol.17 , pp. 1517-1525
    • Sato, M.1    Morii, E.2    Komori, T.3    Sato, M.4    Morii, E.5    Komori, T.6
  • 9
    • 1542677035 scopus 로고    scopus 로고
    • The osteoblast transcription factor Runx2 is expressed in mammary epithelial cells and mediates osteopontin expression
    • Inman CK, Shore P. The osteoblast transcription factor Runx2 is expressed in mammary epithelial cells and mediates osteopontin expression. J Biol Chem 2003; 278: 48684-48689.
    • (2003) J. Biol. Chem. , vol.278 , pp. 48684-48689
    • Inman, C.K.1    Shore, P.2
  • 10
    • 0037843323 scopus 로고    scopus 로고
    • Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells
    • Barnes GL, Javed A, Waller SM, Kamal MH, Hebert KE, Hassan MQ et al. Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res 2003; 63: 2631-2637.
    • (2003) Cancer Res. , vol.63 , pp. 2631-2637
    • Barnes, G.L.1    Javed, A.2    Waller, S.M.3    Kamal, M.H.4    Hebert, K.E.5    Hassan, M.Q.6
  • 12
    • 0942279489 scopus 로고    scopus 로고
    • Transcriptional regulation of human osteopontin promoter by C/EBPalpha and AML-1 in metastatic cancer cells
    • Liu YN, Kang BB, Chen JH. Transcriptional regulation of human osteopontin promoter by C/EBPalpha and AML-1 in metastatic cancer cells. Oncogene 2004; 23: 278-288.
    • (2004) Oncogene , vol.23 , pp. 278-288
    • Liu, Y.N.1    Kang, B.B.2    Chen, J.H.3
  • 14
    • 0029999603 scopus 로고    scopus 로고
    • Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin
    • Senger DR, Ledbetter SR, Claffey KP, Papadopoulos-Sergiou A, Peruzzi CA, Detmar M. Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin. Am J Pathol 1996; 149: 293-305.
    • (1996) Am. J. Pathol. , vol.149 , pp. 293-305
    • Senger, D.R.1    Ledbetter, S.R.2    Claffey, K.P.3    Papadopoulos-Sergiou, A.4    Peruzzi, C.A.5    Detmar, M.6
  • 15
    • 0028118893 scopus 로고
    • Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro
    • Liaw L, Almeida M, Hart CE, Schwartz SM, Giachelli CM. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res 1994; 74: 214-224.
    • (1994) Circ. Res. , vol.74 , pp. 214-224
    • Liaw, L.1    Almeida, M.2    Hart, C.E.3    Schwartz, S.M.4    Giachelli, C.M.5
  • 17
    • 0142026839 scopus 로고    scopus 로고
    • Osteopontin overproduced by tumor cells acts as a potent angiogenic factor contributing to tumor growth
    • Hirama M, Takahashi F, Takahashi K, Akutagawa S, Shimizu K, Soma S et al. Osteopontin overproduced by tumor cells acts as a potent angiogenic factor contributing to tumor growth. Cancer Lett 2003; 198: 107-117.
    • (2003) Cancer Lett. , vol.198 , pp. 107-117
    • Hirama, M.1    Takahashi, F.2    Takahashi, K.3    Akutagawa, S.4    Shimizu, K.5    Soma, S.6
  • 18
    • 0037088640 scopus 로고    scopus 로고
    • Tumor-derived osteopontin is soluble, not matrix associated
    • Rittling SR, Chen Y, Feng F, Wu Y. Tumor-derived osteopontin is soluble, not matrix associated. J Biol Chem 2002; 277: 9175-9182.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9175-9182
    • Rittling, S.R.1    Chen, Y.2    Feng, F.3    Wu, Y.4
  • 19
    • 0043238919 scopus 로고    scopus 로고
    • Differential expression of osteopontin and bone sialoprotein in bone metastasis of breast and prostate carcinoma
    • Carlinfante G, Vassiliou D, Svensson O, Wendel M, Heinegard D, Andersson G. Differential expression of osteopontin and bone sialoprotein in bone metastasis of breast and prostate carcinoma. Clin Exp Metast 2003; 20: 437-444.
    • (2003) Clin. Exp. Metast. , vol.20 , pp. 437-444
    • Carlinfante, G.1    Vassiliou, D.2    Svensson, O.3    Wendel, M.4    Heinegard, D.5    Andersson, G.6
  • 20
    • 0142215535 scopus 로고    scopus 로고
    • Enhanced production of osteopontin in multiple myeloma: Clinical and pathogenic implications
    • Saeki Y, Mima T, Ishii T, Ogata A, Kobayashi H, Ohshima S et al. Enhanced production of osteopontin in multiple myeloma: Clinical and pathogenic implications. Br J Haematol 2003; 123: 263-270.
    • (2003) Br. J. Haematol. , vol.123 , pp. 263-270
    • Saeki, Y.1    Mima, T.2    Ishii, T.3    Ogata, A.4    Kobayashi, H.5    Ohshima, S.6
  • 21
    • 2942606661 scopus 로고    scopus 로고
    • Osteopontin is an adhesive factor for myeloma cells and is found in increased levels in plasma from patients with multiple myeloma
    • Standal T, Hjorth-Hansen H, Rasmussen T, Dahl IM, Lenhoff S, Brenne AT et al, Osteopontin is an adhesive factor for myeloma cells and is found in increased levels in plasma from patients with multiple myeloma. Haematologica 2004; 89: 174-182.
    • (2004) Haematologica , vol.89 , pp. 174-182
    • Standal, T.1    Hjorth-Hansen, H.2    Rasmussen, T.3    Dahl, I.M.4    Lenhoff, S.5    Brenne, A.T.6
  • 25
    • 1842631409 scopus 로고    scopus 로고
    • Osteopontin enhances the cell proliferation induced by the epidermal growth factor in human prostate cancer cells
    • Angelucci A, Festuccia C, Gravina GL, Muzi P, Bonghi L, Vicentini C et al. Osteopontin enhances the cell proliferation induced by the epidermal growth factor in human prostate cancer cells. Prostate 2004; 59: 157-166.
    • (2004) Prostate , vol.59 , pp. 157-166
    • Angelucci, A.1    Festuccia, C.2    Gravina, G.L.3    Muzi, P.4    Bonghi, L.5    Vicentini, C.6
  • 26
    • 11144355973 scopus 로고    scopus 로고
    • Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells
    • Castellone MD, Celetti A, Guarino V, Cirafici AM, Basolo F, Giannini R et al. Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/ PTC-transformed thyroid cells. Oncogene 2004; 23: 2188-2196.
    • (2004) Oncogene , vol.23 , pp. 2188-2196
    • Castellone, M.D.1    Celetti, A.2    Guarino, V.3    Cirafici, A.M.4    Basolo, F.5    Giannini, R.6
  • 27
    • 0027979437 scopus 로고
    • Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA
    • Behrend EI, Craig AM, Wilson SM, Denhardt DT, Chambers AF. Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA. Cancer Res 1994; 54: 832-837.
    • (1994) Cancer Res. , vol.54 , pp. 832-837
    • Behrend, E.I.1    Craig, A.M.2    Wilson, S.M.3    Denhardt, D.T.4    Chambers, A.F.5
  • 28
    • 4944230728 scopus 로고    scopus 로고
    • Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: A vicious cycle between bone destruction and myeloma expansion
    • Abe M, Hiura K, Wilde J, Shioyasono A, Moriyama K, Hashimoto T et al. Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: A vicious cycle between bone destruction and myeloma expansion. Blood 2004; 104: 2484-2491.
    • (2004) Blood , vol.104 , pp. 2484-2491
    • Abe, M.1    Hiura, K.2    Wilde, J.3    Shioyasono, A.4    Moriyama, K.5    Hashimoto, T.6
  • 29
    • 2642548422 scopus 로고    scopus 로고
    • IL-6 regulates CD44 cell surface expression on human myeloma cells
    • Vincent T, Mechti N. IL-6 regulates CD44 cell surface expression on human myeloma cells. Leukemia 2004; 18: 967-975.
    • (2004) Leukemia , vol.18 , pp. 967-975
    • Vincent, T.1    Mechti, N.2
  • 30
    • 0034069657 scopus 로고    scopus 로고
    • Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor
    • Lin YH, Huang CJ, Chao JR, Chen ST, Lee SF, Yen JJ et al. Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor. Mol Cell Biol 2000; 20: 2734-2742.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 2734-2742
    • Lin, Y.H.1    Huang, C.J.2    Chao, J.R.3    Chen, S.T.4    Lee, S.F.5    Yen, J.J.6
  • 32
    • 0035976914 scopus 로고    scopus 로고
    • Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells
    • Philip S, Bulbule A, Kundu GC. Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells. J Biol Chem 2001; 276: 44926-44935.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44926-44935
    • Philip, S.1    Bulbule, A.2    Kundu, G.C.3
  • 33
    • 0030744830 scopus 로고    scopus 로고
    • Metalloproteinases in multiple myeloma: Production of matrix metalloproteinase-9 (MMP-9), activation of proMMP-2, and induction of MMP-1 by myeloma cells
    • Barille S, Akhoundi C, Collette M, Mellerin MP, Rapp MJ, Harousseau JL et al. Metalloproteinases in multiple myeloma: Production of matrix metalloproteinase-9 (MMP-9), activation of proMMP-2, and induction of MMP-1 by myeloma cells. Blood 1997; 90: 1649-1655.
    • (1997) Blood , vol.90 , pp. 1649-1655
    • Barille, S.1    Akhoundi, C.2    Collette, M.3    Mellerin, M.P.4    Rapp, M.J.5    Harousseau, J.L.6
  • 35
    • 0034984151 scopus 로고    scopus 로고
    • Minireview: Transcriptional control of osteoblast differentiation
    • Karsenty G. Minireview: Transcriptional control of osteoblast differentiation. Endocrinology 2001; 142: 2731-2733.
    • (2001) Endocrinology , vol.142 , pp. 2731-2733
    • Karsenty, G.1
  • 36
    • 0029875552 scopus 로고    scopus 로고
    • Ectopic secretion of osteocalcin, the major non-collagenous bone protein, by the myeloma cell line NCI-H929
    • Barille S, Pellat-Deceunynck C, Bataille R, Amiot M. Ectopic secretion of osteocalcin, the major non-collagenous bone protein, by the myeloma cell line NCI-H929. J Bone Miner Res 1996; 11: 466-471.
    • (1996) J. Bone Miner. Res. , vol.11 , pp. 466-471
    • Barille, S.1    Pellat-Deceunynck, C.2    Bataille, R.3    Amiot, M.4
  • 37
    • 12244296438 scopus 로고    scopus 로고
    • Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells
    • Shui C, Spelsberg TC, Riggs BL, Khosla S. Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells. J Bone Miner Res 2003; 18: 213-221.
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 213-221
    • Shui, C.1    Spelsberg, T.C.2    Riggs, B.L.3    Khosla, S.4
  • 38
    • 0037926821 scopus 로고    scopus 로고
    • AML-1A and AML-1B regulation of MIP-1alpha expression in multiple myeloma
    • Choi SJ, Oba T, Callander NS, Jelinek DF, Roodman GD. AML-1A and AML-1B regulation of MIP-1alpha expression in multiple myeloma. Blood 2003; 101: 3778-3783.
    • (2003) Blood , vol.101 , pp. 3778-3783
    • Choi, S.J.1    Oba, T.2    Callander, N.S.3    Jelinek, D.F.4    Roodman, G.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.