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Oka S, Bruses JL, Nelson RW, Rutishauser U: Properties and developmental regulation of polysialyltransferase activity in the chicken embryo brain. J Biol Chem 1995, 270:19357-19363. As a characterization of polysialytransferase activity in tissues, this study provides a basis for testing the biological relevance of the cloned enzymes described in [8**-11**).
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NCAM mutation inhibits tangential neuronal migration and is phenocopied by enzymatic removal of polysialic acid
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Nelson RW, Bates PA, Rutishauser U: Protein determinants for specific polysialylation of the neural cell adhesion molecule. J Biol Chem 1995, 270:17171-17179. One of the most unusual aspects of PSA is its specific addition to NCAM. This study establishes that this specificity is achieved through the concerted action of three adjacent domains of NCAM, resulting in polymer addition to a subset of potential glycosylation sites.
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Bruses J, Oka S, Rutishauser U: NCAM-associated polysialic acid on ciliary ganglion neurons is regulated by polysialyltransferase levels and interaction with muscle. J Neurosci 1995, 15:8310-8319. An in vitro assay combining muscle cells and motoneurons is used to establish that direct contact between these two cell types directly alters polysialytransferase activity.
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Tang J, Rutishauser U, Landmesser L: Polysialic acid regulates growth cone behavior during sorting of motor axons in the plexus region. Neuron 1994, 13:405-414.
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Neuron
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Effect of polysialic acid on the behavior of retinal ganglion cell axons during growth into the optic tract and tectum
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Yin X, Cai X, Rutishauser U: Effect of polysialic acid on the behavior of retinal ganglion cell axons during growth into the optic tract and tectum. Development 1994, 121:3439-3446.
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Polysialylated NCAM and plasticity of ipsilateral connections in Xenopus tectum
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Chain migration of neuronal precursors
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Lois C, Garcia-Verdugo J-M, Alvarez-Buylla A: Chain migration of neuronal precursors. Science 1996, 271:978-981. One of a series of recent publications suggesting that PSA promotes a novel mode of neural cell migration in which cells appear to migrate cooperatively in streams. See also [23*,24*].
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Science
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Lois, C.1
Garcia-Verdugo, J.-M.2
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23
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Embryonic (PSA) N-CAM reveals chains of migrating neuroblasts between the lateral ventricle and the olfactory bulb of adult mice
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Rousselot P, Lois C, Alvarez-Buylla A: Embryonic (PSA) N-CAM reveals chains of migrating neuroblasts between the lateral ventricle and the olfactory bulb of adult mice. J Comp Neurol 1995, 351:51-61. See annotation [22*].
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The role of polysialic acid in the migration of olfactory interneuron precursors in the subventricular zone
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Hu H, Tomasiewicz H, Magnuson T, Rutishauser U: The role of polysialic acid in the migration of olfactory interneuron precursors in the subventricular zone. Neuron 1996, 16:735-743. See annotation [22*]. NCAM-deficient mice and endoneuramidase are used both to prove that cell streaming is causally related to PSA expression, and to investigate the mechanism of that migration.
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Neuron
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Hu, H.1
Tomasiewicz, H.2
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Requirement of polysialic acid for the migration of O-2A glial progenitor cells from neurohypophyseal explants
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The migration of luteinizing hormone-releasing hormone neurons in the developing rat is associated with a transient, caudal projection of the vomeronasal nerve
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0028923708
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Expression of neural cell adhesion molecules, NCAM's, and their polysialylated forms, PSA-NCAM's in the developing pituitary gland
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Berardi M, Hindelang C, Lairent-Huck FM, Langley K, Rougon G, Felix JM, Stoekli ME: Expression of neural cell adhesion molecules, NCAM's, and their polysialylated forms, PSA-NCAM's in the developing pituitary gland. Cell Tissue Res 1995, 280:463-472.
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0028943937
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Posterior extension of the chick nephric (Wolffian) duct the role of fibronectin and NCAM polysiallc acid
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Bellairs R, Lear P, Yamada KM, Rutishauser U, Lash JW: Posterior extension of the chick nephric (Wolffian) duct: the role of fibronectin and NCAM polysiallc acid. Dev Dyn 1995, 202:333-342.
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Dev Dyn
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Bellairs, R.1
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Expression of polysialylated neural cell adhesion molecules in the suprachiasmatic nucleus evidence for plasticity in the adult mammalian circadian pacemaker
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Expression of polysialylated N-CAM in the central nervous system of adult canaries and its possible relation to function
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Rousselot PN, Nottebohm F: Expression of polysialylated N-CAM in the central nervous system of adult canaries and its possible relation to function. J Comp Neurol 1995, 356:629-640. One of a group of publications that suggest that the persistent expression of PSA in the adult brain may be related to plasticity in higher-order neural function. See also [31, 33].
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J Comp Neurol
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In vitro and in vivo growth of clonal sublines of human small cell lung carcinoma is modulated by polysialic acid of the neural cell adhesion molecule
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Scheidegger EP, Lackie PM, Papay J, Roth J: In vitro and in vivo growth of clonal sublines of human small cell lung carcinoma is modulated by polysialic acid of the neural cell adhesion molecule. Lab Invest 1994, 70:95-106.
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Embryonic neural cell adhesion molecule (NCAM) is elevated in the denervated rat dentate gyrus
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Miller PD, Styren SD, Lagenaur CF, DeKosky ST: Embryonic neural cell adhesion molecule (NCAM) is elevated in the denervated rat dentate gyrus. J Neurosci 1994, 14:4217-4225.
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Polysialylated neural cell adhesion molecule expression by neurons and astroglia cell processes in the rat dentate gyrus decreases dramatically with increasing age
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Fox GB, Kennedy N, Regan CM: Polysialylated neural cell adhesion molecule expression by neurons and astroglia cell processes in the rat dentate gyrus decreases dramatically with increasing age. Int J Dev Neurosci 1995, 13:663-672.
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Seki, T.1
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0028346526
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Decrease in growth cone-neurite fasciculation by sensory or motor neurons in vitro accompanies downregulation of Aplysia cell adhesion molecules by neurotransmitters
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Peter N, Aronoff B, Wu F, Schacher S: Decrease in growth cone-neurite fasciculation by sensory or motor neurons in vitro accompanies downregulation of Aplysia cell adhesion molecules by neurotransmitters. J Neurosci 1994, 14:1413-1421.
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Peter, N.1
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Changes in expression and distribution of Aplysia cell adhesion molecules can influence synapse formation and elimination in vitro
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Zhu H, Wu F, Schacher S: Changes in expression and distribution of Aplysia cell adhesion molecules can influence synapse formation and elimination in vitro. J Neurosci 1995, 15:4173-4183. The two mostly closely NCAM-related receptors are apCAM in Aplysia and fasciclin II in Drosophila, yet the invertebrate versions do not carry PSA. These papers indicate that despite this difference in structure, each of these NCAM-like molecules is involved in a similar function, namely the regulation of cell interactions that affect the guidance and/or plasticity of neurons. See text for further discussion of this interesting comparison. See also [39, 41, 42].
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Zhu, H.1
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Genetic analysis of fasciclin II in Drosophila defasciculation, refasciculation and altered fasciculation
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Lin DM, Fetter RD, Kopczynski C, Grenningloh G, Goodman CS: Genetic analysis of fasciclin II in Drosophila: defasciculation, refasciculation and altered fasciculation. Neuron 1994, 13:1055-1069.
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Lin, D.M.1
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Ectopic and increased expression of fasciclin II alters motoneuron growth cone guidance
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Lin DM, Goodman CS: Ectopic and increased expression of fasciclin II alters motoneuron growth cone guidance. Neuron 1994, 13:507-523.
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0025345081
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Polysialic acid as a regulator of intramuscular nerve branching during embryonic development
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0029843864
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Spatially restricted increase in polysialic acid enhances corticospinal axon branching related to target recognition and innervation
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in press
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Daston MM, Bastmeyer M, Rutishauser U, O'Leary DDM: Spatially restricted increase in polysialic acid enhances corticospinal axon branching related to target recognition and innervation [abstract]. J Neurosci 1996, in press.
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Daston, M.M.1
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0027730439
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Genetic deletion of a neural cell adhesion molecule variant (NCAM-180) produces distinct defects in the central nervous system
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Tomasiewicz H, Ono K, Yee D, Thompson C, Goridis C, Rutishauser U, Magnuson T: Genetic deletion of a neural cell adhesion molecule variant (NCAM-180) produces distinct defects in the central nervous system. Neuron 1993, 11:1163-1174.
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Tomasiewicz, H.1
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0027771712
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Regulation and activity-dependence of N-cadherin, NCAM isoforms and polysialic acid on chick myotubes during development
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