Distribution of androgen receptor CAG repeat polymorphism in Chinese schizophrenia and its correlation with age at onset

Psychoneuroendocrinology

Volumn 31, Issue 2, 2006, Pages 270-274

  Tsai, Shih Jen ^a,b   Hong, Chen Jee ^a,b   Liao, Ding Lieh ^c   Chiang, Chih Hung ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c Pali Psychiatric Hospital   (Taiwan)

Author keywords

Age at onset; Androgen receptor; Association study; Polymorphism; Schizophrenia

Indexed keywords

ANDROGEN RECEPTOR;

ADULT; ALLELE; ARTICLE; CHINESE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA POLYMORPHISM; FEMALE; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; MALE; ONSET AGE; PRIORITY JOURNAL; SCHIZOPHRENIA; SYMPTOMATOLOGY; TRINUCLEOTIDE REPEAT;

ADULT; AGE OF ONSET; CHINA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, ANDROGEN; SCHIZOPHRENIA; TRINUCLEOTIDE REPEATS;

EID: 28444497810     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2005.06.006     Document Type: Article

References (18)

1. M.C. Angermeyer, and L. Kuhn Gender differences in age at onset of schizophrenia. An overview Eur. Arch. Psychiatry Neurol. Sci. 237 1988 351 364
2. M. Arranz, T. Sharma, P. Sham, R. Kerwin, S. Nanko, M. Owen, M. Gill, and D. Collier Schizophrenia and the androgen receptor gene: report of a sibship showing co-segregation with Reifenstein syndrome but no evidence for linkage in 23 multiply affected families Am. J. Med. Genet. 60 1995 377 381
3. C.J. Brown, S.J. Goss, D.B. Lubahn, D.R. Joseph, E.M. Wilson, F.S. French, and H.F. Willard Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA polymorphism Am. J. Hum. Genet. 44 1989 264 269
4. R. Casella, M.R. Maduro, L.I. Lipshultz, and D.J. Lamb Significance of the polyglutamine tract polymorphism in the androgen receptor Urology 58 2001 651 656
5. C.S. Choong, J.A. Kemppainen, Z.X. Zhou, and E.M. Wilson Reduced androgen receptor gene expression with first exon CAG repeat expansion Mol. Endocrinol. 10 1996 1527 1535
6. T.J. Crow, M. Poulter, R. Lofthouse, G. Chen, T. Shah, N. Bass, C. Morganti, A. Vita, C. Smith, and A. Boccio-Smith Male siblings with schizophrenia share alleles at the androgen receptor above chance expectation Am. J. Med. Genet. 48 1993 159 160
7. L.E. DeLisi, U. Friedrich, J. Wahlstrom, A. Boccio-Smith, A. Forsman, K. Eklund, and T.J. Crow Schizophrenia and sex chromosome anomalies Schizophr. Bull. 20 1994 495 505
8. A. Edwards, H.A. Hammond, L. Jin, C.T. Caskey, and R. Chakraborty Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups Genomics 12 1992 241 253
9. G. Fink, B. Sumner, R. Rosie, H. Wilson, and J. McQueen Androgen actions on central serotonin neurotransmission: relevance for mood, mental state and memory Behav. Brain Res. 105 1999 53 68
10. H. Hafner, W. an der Heiden, S. Behrens, W.F. Gattaz, M. Hambrecht, W. Loffler, K. Maurer, P. Munk-Jorgensen, B. Nowotny, A. Riecher-Rossler, and A. Stein Causes and consequences of the gender difference in age at onset of schizophrenia Schizophr. Bull. 24 1998 99 113
11. T.J. Huber, C. Tettenborn, E. Leifke, and H.M. Emrich Sex hormones in psychotic men Psychoneuroendocrinology 30 2005 111 114
12. E.G. Jonsson, C. von Gertten, J.P. Gustavsson, Q.P. Yuan, K. Lindblad-Toh, K. Forslund, G. Rylander, M. Mattila-Evenden, M. Asberg, and M. Schalling Androgen receptor trinucleotide repeat polymorphism and personality traits Psychiatr. Genet. 11 2001 19 23
13. R.D. Oades, and R. Schepker Serum gonadal steroid hormones in young schizophrenic patients Psychoneuroendocrinology 19 1994 373 385
14. G. Pelletier Localization of androgen and estrogen receptors in rat and primate tissues Histol. Histopathol. 15 2000 1261 1270
15. M.A. Roy, M. Maziade, A. Labbe, and C. Merette Male gender is associated with deficit schizophrenia: a meta-analysis Schizophr. Res. 47 2001 141 147
16. S.N. Seidman, A.B. Araujo, S.P. Roose, and J.B. McKinlay Testosterone level, androgen receptor polymorphism, and depressive symptoms in middle-aged men Biol. Psychiatry 50 2001 371 376
17. K. Yaffe, E.R. Edwards, L.Y. Lui, J.M. Zmuda, R.E. Ferrell, and J.A. Cauley Androgen receptor CAG repeat polymorphism is associated with cognitive function in older men Biol. Psychiatry 54 2003 943 946
18. J. Yan, J. Feng, D. Goldman, E.H. Cook Jr, N. Craddock, I.R. Jones, L.L. Heston, and S.S. Sommer Mutation scanning of the androgen receptor gene in patients with psychiatric disorders reveals highly conserved variants in alcoholic and phobia patients Psychiatr. Genet. 14 2004 57 60