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Volumn , Issue 23, 2005, Pages 5094-5099

Facile access to isotopically labelled valylleucyl anilides as biomarkers for the quantification of hemoglobin adducts to toxic electrophiles

Author keywords

Biomarkers; Hemoglobin adducts; Isotopic labelling; Peptidomimetics; Toxicology

Indexed keywords


EID: 28444472800     PISSN: 1434193X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ejoc.200500429     Document Type: Article
Times cited : (4)

References (45)
  • 24
    • 28444479369 scopus 로고    scopus 로고
    • note
    • 13C (98.9% L-form) is produced by ISOTEC Inc. (USA) and was purchased from SIGMA-ALDRICH.
  • 25
    • 28444474463 scopus 로고    scopus 로고
    • note
    • The amino acid sequence of Hb at the N-terminus starts from H-Val-Leu-Ser-Pro-Ala-Asp-Lys.
  • 26
    • 28444432227 scopus 로고    scopus 로고
    • note
    • E. g., from the BACHEM company (Switzerland).
  • 27
    • 28444467299 scopus 로고    scopus 로고
    • note
    • 15N) fragment.
  • 29
    • 33645345747 scopus 로고    scopus 로고
    • Rep. No. 40
    • Deutsche Forschungsgemeinschaft, Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, List of MAK and BAT Values, 2004, Rep. No. 40.
    • (2004) List of MAK and BAT Values
  • 30
    • 0024970539 scopus 로고
    • Reductive alkylation of another dipeptide - Nα-alanylhistidine - with glycerin aldehyde has been reported, but without practically important experimental details: N. Mori, Y. Bai, H. Ueno, J. M. Manning, Carbohydr. Res. 1989, 189, 49-64.
    • (1989) Carbohydr. Res. , vol.189 , pp. 49-64
    • Mori, N.1    Bai, Y.2    Ueno, H.3    Manning, J.M.4
  • 31
    • 28444438411 scopus 로고    scopus 로고
    • note
    • Unlike with aldehydes, cyclopentanone and cyclohexanone, reductive alkylation with sterically more cqnjested ketones affords the single product of monoalkylation (V. Belov, unpublished results).
  • 32
    • 28444477236 scopus 로고    scopus 로고
    • note
    • Purchased from the BACHEM company (Switzerland).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.