An alternative fast and convenient genotyping method for the screening of angiotensin converting enzyme gene polymorphisms

Hypertension Research

Volumn 26, Issue 4, 2003, Pages 301-306

  Tanaka, Chihiro ^a   Kamide, Kei ^a   Takiuchi, Shin ^a   Miwa, Yoshikazu ^a   Yoshii, Masayoshi ^a   Kawano, Yuhei ^a   Miyata, Toshiyuki ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Angiotensin converting enzyme; Genotyping; Insertion deletion polymorphism; Testicular angiotensin converting enzyme

Indexed keywords

AMINO ACID; DIPEPTIDYL CARBOXYPEPTIDASE;

ALLELE; ANGIOTENSIN BLOOD LEVEL; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC KIT; DIAGNOSTIC VALUE; DNA POLYMORPHISM; ENZYME LOCALIZATION; EXON; GENE DELETION; GENE INSERTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC CODE; GENETIC SCREENING; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PROTEIN FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TESTIS; TIME;

ADULT; ALLELES; BASE SEQUENCE; DNA; GENETIC SCREENING; GENOTYPE; HUMANS; HYPERTENSION; LINKAGE DISEQUILIBRIUM; MALE; MOLECULAR SEQUENCE DATA; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE DELETION; TESTIS;

EID: 0037986824     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.26.301     Document Type: Article

References (22)

1. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F: An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990; 86: 1343-1346.
2. Kato H: Genetic analysis in human hypertension. Hypertens Res 2002; 25:319-327.
3. Schunkert H: Polymorphism of the angiotensin-converting enzyme gene and cardiovascular disease. J Mol Med 1997; 75: 867-875.
4. Soubrier F, Nadaud S, Williams TA: Angiotensin I converting enzyme gene: regulation, polymorphism and implications in cardiovascular diseases. Eur Heart J 1994; 15: 24-29.
5. Cambien F, Poirier O, Lecerf L, et al: Deletion polymerphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-644.
6. Higaki J, Baba S, Katsuya T, et al: Deletion allele of angiotensin-converting enzyme gene increases risk of essential hypertension in Japanese men: the Suita study. Circulation 2000; 101: 2060-2065.
7. Gesang L, Liu G, Cen W, et al: Angiotensin-converting enzyme gene polymorphism and its association with essential hypertension in a Tibetan population. Hypertens Res 2002; 25: 481-485.
8. Iwai N, Ohmichi N, Nakamura Y, Kinoshita M: DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy. Circulation 1994; 90: 2622-2628.
9. Schmidt S, van Hooft IM, Grobbee DE, Ganten D, Ritz E: Polymorphism of the angiotensin I converting enzyme gene is apparently not related to high blood pressure: Dutch Hypertension and Offspring Study. J Hypertens 1993; 11: 345-348.
10. Wu S, Hong J, Li H, et al: No correlation of polymorphism of angiotensin-converting enzyme genes with left ventricular hypertrophy in essential hypertension. Hypertens Res 2000; 23: 261-264.
11. Villard E, Tiret L, Visvikis S, Rakotovao R, Cambien F, Soubrier F: Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis. Am J Hum Genet 1996; 58: 1268-1278.
12. Zhu X, Bouzekri N, Southam L, et al: Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure. Am J Hum Genet 2001; 68: 1139-1148.
13. Lindpaintner K, Pfeffer MA, Kreutz R, et al: A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med 1995; 332: 706-711.
14. Rieder MJ, Taylor SL, Clark AG, Nickerson DA: Sequence variation in the human angiotensin converting enzyme. Nat Genet 1999; 22: 59-62.
15. Okuda T, Fujioka Y, Kamide K, et al: Verification of 525 coding SNPs in 179 hypertension candidate genes in the Japanese population: identification of 159 SNPs in 93 genes. J Hum Genet 2002; 47: 387-394.
16. Rigat B, Hubert C, Corvol P, Soubrier F: PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acids Res 1992; 20: 1433.
17. Foy CA, Rice GI, Ossei-Gerning N, Mansfield MW, Grant PJ: Angiotensin-converting enzyme (ACE) gene polymorphisms in patients characterized by coronary angiography. Hum Genet 1997; 100: 420-425.
18. Farrall M, Keavney B, McKenzie C, Delepine M, Matsuda F, Lathrop GM: Fine-mapping of an ancestral recombination breakpoint in DCP1. Nat Genet 1999; 23: 270-271.
19. Soubrier F, Martin S, Alonso A, et al: High-resolution genetic mapping of the ACE-linked QTL influencing circulating ACE activity. Eur J Hum Genet 2002; 10: 553-561.
20. Soubrier F, Alhenc-Gelas F, Hubert C, et al: Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci U S A 1988; 85: 9386-9390.
21. Ehlers MR, Fox EA, Strydom DJ, Riordan JF: Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme. Proc Natl Acad Sci U S A 1989; 86: 7741-7745.
22. Hubert C, Houot AM, Corvol P, Soubrier F: Structure of the angiotensin I-converting enzyme gene: two alternate promoters correspond to evolutionary steps of a duplicated gene. J Biol Chem 1991; 266; 23: 15377-15383.