Neutralization of tumor necrosis factor alpha suppresses antigen-specific type 1 cytokine responses and reverses the inhibition of mycobacterial survival in cocultures of immune guinea pig T lymphocytes and infected macrophages

Infection and Immunity

Volumn 73, Issue 12, 2005, Pages 8437-8441

  Cho, Hyosun ^a   McMurray, David N ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 12P40; MESSENGER RNA; TUBERCULIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BACTERIAL VIRULENCE; BCG VACCINATION; BONE MARROW CELL; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GUINEA PIG; LYMPHOCYTE PROLIFERATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SPLEEN CELL; T LYMPHOCYTE; TUBERCULOSIS;

ANIMALS; ANTIBODIES; ANTIGENS, BACTERIAL; CELL PROLIFERATION; COCULTURE TECHNIQUES; CYTOKINES; GUINEA PIGS; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P40; MACROPHAGES, PERITONEAL; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN SUBUNITS; RNA, MESSENGER; SPLEEN; TH1 CELLS; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 28444447060     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.12.8437-8441.2005     Document Type: Article

References (27)

1. Allen, S. S., and D. N. McMurray. 2003. Coordinate cytokine gene expression in vivo following induction of tuberculous pleurisy in guinea pigs. Infect. Immun. 71:4271-4277.
2. Baldwin, S. L., C. D'Souza, A. D. Roberts, B. P. Kelly, A. A. Frank, M. A. Lui, J. B. Ulmer, K. Huygen, D. M. McMurray, and I. M. Orme. 1998. Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis. Infect. Immun. 66:2951-2959.
3. Barrera, L. F., E. Skamene, and D. Radzioch. 1993. Assessment of mycobacterial infection and multiplication in macrophages by polymerase chain reaction. J. Immunol. Methods 157:91-99.
4. Bean, A. G., D. R. Roach, H. Briscoe, M. P. France, H. Korner, J. D. Sedgwick, and W. J. Britton. 1999. Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin. J. Immunol. 162:3504-3511.
5. Boom, W. H., D. H. Canaday, S. A. Fulton, A. J. Gehring, R. E. Rojas, and M. Torres. 2003. Human immunity to M. tuberculosis: T cell subsets and antigen processing. Tuberculosis (Edinburgh) 83:98-106.
6. Britton, W. J., N. Meadows, D. A. Rathjen, D. R. Roach, and H. Briscoe. 1998. A tumor necrosis factor mimetic peptide activates a murine macrophage cell line to inhibit mycobacterial growth in a nitric oxide-dependent fashion. Infect. Immun. 66:2122-2127.
7. Cho, H., T. M. Lasco, S. S. Allen, T. Yoshimura, and D. N. McMurray. 2005. Recombinant guinea pig tumor necrosis factor alpha stimulates the expression of interleukin-12 and the inhibition of Mycobacterium tuberculosis growth in macrophages. Infect. Immun. 73:1367-1376.
8. Engele, M., E. Stossel, K. Castiglione, N. Schwerdtner, M. Wagner, P. Bolcskei, M. Rollinghoff, and S. Stenger. 2002. Induction of TNF in human alveolar macrophages as a potential evasion mechanism of virulent Mycobacterium tuberculosis. J. Immunol. 168:1328-1337.
9. Flesch, I. E., J. H. Hess, S. Huang, M. Aguet, J. Rothe, H. Bluethmann, and S. H. Kaufmann. 1995. Early interleukin 12 production by macrophages in response to mycobacterial infection depends on Interferon gamma and tumor necrosis factor alpha. J. Exp. Med. 181:1615-1621.
10. Flynn, J. L. 2004. Immunology of tuberculosis and implications in vaccine development. Tuberculosis 84:93-101.
11. Flynn, J. L., and J. Chan. 2001. Immunology of tuberculosis. Annu. Rev. Immunol. 19:93-129.
12. Greinert, U., M. Ernst, M. Schlaak, and P. Entzian. 2001. Interleukin-12 as successful adjuvant in tuberculosis treatment. Eur. Respir. J. 17:1049-1051.
13. Herring, A. C., J. Lee, R. A. McDonald, G. B. Toews, and G. B. Huffnagle. 2002. Induction of interleukin-12 and gamma interferon requires tumor necrosis factor alpha for protective Tl-cell-mediated immunity to pulmonary Cryptococcus neoformans infection. Infect. Immun. 70:2959-2964.
14. Kawakami, K., Y. Kinjo, K. Uezu, K. Miyagi, T. Kinjo, S. Yara, Y. Koguchi, A. Miyazato, K. Shibuya, Y. Iwakura, K. Takeda, S. Akira, and A. Saito. 2004. Interferon-gamma production and host protective response against Mycobacterium tuberculosis in mice lacking both IL-12p40 and IL-18. Microbes Infect. 6:339-349.
15. Lasco, T. M., T. Yamamoto, T. Yoshimura, S. S. Allen, L. Cassone, and D. N. McMurray. 2003. Effect of Mycobacterium bovis BCG vaccination on mycobacterium-specific bacterium-specific cellular proliferation and tumor necrosis factor alpha production from distinct guinea pig leukocyte populations. Infect. Immun. 71:7035-7042.
16. Levin, M., and M. Newport. 1999. Understanding the genetic basis of susceptibility to mycobacterial infection. Proc. Assoc. Am. Phys. 111:308-312.
17. Mainali, E. S., and D. N. McMurray. 1998. Protein deficiency induces alterations in the distribution of T-cell subsets in experimental pulmonary tuberculosis. Infect. Immun. 66:927-931.
18. McMurray, D. N. 2001. Disease model: pulmonary tuberculosis. Trends Mol. Med. 7:135-137.
19. Michishita, M., Y. Yoshida, H. Uchino, and K. Nagata. 1990. Induction of tumor necrosis factor-alpha and its receptors during differentiation in myeloid leukemic cells along the monocytic pathway. A possible regulatory mechanism for TNF-alpha production. J. Biol. Chem. 265:8751-8759.
20. Perrin, P. J., T. A. Davis, D. S. Smoot, R. Abe, C. H. June, and K. P. Lee. 1997. Mitogenic stimulation of T cells reveals differing contributions for B7-1 (CD80) and B7-2 (CD86) costimulation. Immunology 90:534-542.
21. Rosenstreich, D. L., J. J. Farrar, and S. Dougherty. 1976. Absolute macrophage dependency of T lymphocyte activation by mitogens. J. Immunol. 116:131-139.
22. Roska, A. K., and P. E. Lipsky. 1985. Dissection of the functions of antigen-presenting cells in the induction of T cell activation. J. Immunol. 135:2953-2961.
23. Schaible, U. E., H. L. Collins, and S. H. Kaufmann. 1999. Confrontation between intracellular bacteria and the immune system. Adv. Immunol. 71: 267-377.
24. Scheurich, P., B. Thoma, U. Ucer, and K. Pfizenmaier. 1987. Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses. J. Immunol. 138:1786-1790.
25. Tanabe, M., T. Matsumoto, K. Shibuya, K. Tateda, S. Miyazaki, A. Nakane, Y. Iwakura, and K. Yamaguchi. 2005. Compensatory response of IL-1 gene knockout mice after pulmonary infection with Klebsiella pneumoniae. J. Med. Microbiol. 54:7-13.
26. Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3:133-146.
27. Yamamura, M., K. Uyemura, R. J. Deans, K. Weinberg, T. H. Rea, B. R. Bloom, and R. L. Modlin. 1991. Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science 254:277-279.