The influence of heterodimer partner ultraspiracle/retinoid X receptor on the function of ecdysone receptor

FEBS Journal

Volumn 272, Issue 23, 2005, Pages 5979-5990

  Palli, Subba R ^a   Kapitskaya, Mariana Z ^b   Potter, David W ^b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b RheoGene Inc   (United States)

Author keywords

Gene switch; Ligand binding domain; Nuclear receptor; Steroid hormone

Indexed keywords

ECDYSONE RECEPTOR; RETINOID X RECEPTOR;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DIMERIZATION; GENE CONTROL; GENE MUTATION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; REPORTER GENE; SIGNAL TRANSDUCTION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; DIMERIZATION; DNA-BINDING PROTEINS; GENES, REPORTER; HUMANS; LIGANDS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHYLOGENY; PROTEIN CONFORMATION; RECEPTORS, STEROID; RECOMBINANT FUSION PROTEINS; RETINOID X RECEPTORS; SEQUENCE ALIGNMENT; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

ANIMALIA; MAMMALIA;

EID: 28244499555     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.05003.x     Document Type: Article

References (37)

1. Koelle MR, Talbot WS, Segraves WA, Bender MT, Cherbas P & Hogness DS (1991) The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily. Cell 67, 59-77.
2. Thomas HE, Stunnenberg HG & Stewart AF (1993) Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle. Nature 362, 471-475.
3. Yao TP, Forman BM, Jiang Z, Cherbas L, Chen JD, McKeown M, Cherbas P & Evans RM (1993) Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature 366, 476-479.
4. Yao TP, Segraves WA, Oro AE, McKeown M & Evans RM (1992) Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. Cell 71, 63-72.
5. Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schutz G, Umesono K, Blumberg B, Kastner P, Mark M & Chambon P (1995) The nuclear receptor superfamily: the second decade. Cell 83, 835-839.
6. Albanese C, Reutens AT, Bouzahzah B, Fu M, D'Amico M, Link T, Nicholson R, Depinho RA & Pestell RG (2000) Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice. FASEB J 14, 877-884.
7. Zhou Y & Ratner L (2001) A novel inducible expression system to study transdominant mutants of HIV-1 Vpr. Virology 287, 133-142.
8. Fussenegger M (2001) The impact of mammalian gene regulation concepts on functional genomic research, metabolic engineering, and advanced gene therapies. Biotechnol Prog 17, 1-51.
9. Yarovoi SV & Pederson T (2001) Human cell lines expressing hormone regulated T7 RNA polymerase localized at distinct intranuclear sites. Gene 275, 73-81.
10. Yam JW, Chan KW & Hsiao WL (2001) Suppression of the tumorigenicity of mutant p53-transformed rat embryo fibroblasts through expression of a newly cloned rat nonmuscle myosin heavy chain-B. Oncogene 20, 58-68.
11. Sparacio S, Pfeiffer T, Schaal H & Bosch V (2001) Generation of a flexible cell line with regulatable, high-level expression of HIV Gag/Pol particles capable of packaging HIV-derived vectors. Mol Ther 3, 602-612.
12. Patrick CW Jr, Zheng B, Wu X, Gurtner G, Barlow M, Koutz C, Chang D, Schmidt M & Evans GR (2001) Muristerone a-induced nerve growth factor release from genetically engineered human dermal fibroblasts for peripheral nerve tissue engineering. Tissue Eng 7, 303-311.
13. Pacchia AL, Adelson ME, Kaul M, Ron Y & Dougherty JP (2001) An inducible packaging cell system for safe, efficient lentiviral vector production in the absence of HIV-1 accessory proteins. Virology 282, 77-86.
14. Lin G & Stern R (2001) Plasma hyaluronidase (Hyal-1) promotes tumor cell cycling. Cancer Lett 163, 95-101.
15. Christopherson KS, Mark MR, Bajaj V & Godowski PJ (1992) Ecdysteroid-dependent regulation of genes in mammalian cells by a Drosophila ecdysone receptor and chimeric transactivators. Proc Natl Acad Sci USA 89, 6314-6318.
16. Yang G, Hannan G, Lockett T & Hill R (1995) Functional transfer of an elementary ecdysone gene regulatory system to mammalian cells-transient transfections and stable cell-lines. Eur J Entomol 92, 379-389.
17. No D, Yao TP & Evans RM (1996) Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc Nail Acad Sci USA 93, 3346-3351.
18. Suhr ST, Gil EB, Senut MC & Gage FH (1998) High level transactivation by a modified Bombyx ecdysone receptor in mammalian cells without exogenous retinoid X receptor. Proc Natl Acad Sci USA 95, 7999-8004.
19. Swevers L, Drevet JR, Lunke MD & Iatrou K (1995) The silkmoth homolog of the Drosophila ecdysone receptor (B1 isoform): cloning and analysis of expression during follicular cell differentiation. Insect Biochem Mol Biol 25, 857-866.
20. Hoppe UC, Marban E & Johns DC (2000) Adenovirus-mediated inducible gene expression in vivo by a hybrid ecdysone receptor. Mol Ther 1, 159-164.
21. Saez E, Nelson MC, Eshelman B, Banayo E, Koder A, Cho GJ & Evans RM (2000) Identification of ligands and coligands for the ecdysone-regulated gene switch. Proc Natl Acad Sci USA 97, 14512-14517.
22. Wyborski DL, Bauer JC & Vaillancourt P (2001) Bicistronic expression of ecdysone-inducible receptors in mammalian cells. Biotechniques 31, 618-620,622,624.
23. Palli SR, Kapitskaya MZ, Kumar MB & Cress DE (2003) Improved ecdysone receptor-based inducible gene regulation system. Eur J Biochem 270, 1308-1315.
24. Palli SR, Hormann RE, Schlattner U & Lezzi M (2005) Ecdysteroid receptors and their applications in agriculture and medicine. Vitamins Hormones in press.
25. Billas IM, Iwema T, Gamier JM, Mitschler A, Rochel N & Moras D (2003) Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor. Nature 426, 91-96.
26. Mangelsdorf DJ, Ong ES, Dyck JA & Evans RM (1990) Nuclear receptor that identifies a novel retinoic acid response pathway. Nature 345, 224-229.
27. Vogtli M, Imhof MO, Brown NE, Rauch P, Spindler-Barth M, Lezzi M & Henrich VC (1999) Functional characterization of two Ultraspiracle forms (CtUSP-1 and CtUSP-2) from Chironomus tentans. Insect Biochem Mol Biol 29, 931-942.
28. Chung AC, Durica DS, Clifton SW, Roe BA & Hopkins PM (1998) Cloning of crustacean ecdysteroid receptor and retinoid-X receptor gene homologs and elevation of retinoid-X receptor mRNA by retinoic acid. Mol Cell Endocrinol 139, 209-227.
29. Hayward DC, Bastiani MJ, Trueman JW, Truman JW, Riddiford LM & Ball EE (1999) The sequence of Locusta RXR, homologous to Drosophila Ultraspiracle, and its evolutionary implications. Dev Genes Evol 209, 564-571.
30. Guo X, Harmon MA, Laudet V, Mangelsdorf DJ & Palmer MJ (1997) Isolation of a functional ecdysteroid receptor homologue from the ixodid tick Amblyomma americanum (L.). Insect Biochem Mol Biol 27, 945-962.
31. Tzertzinis G, Malecki A & Kafatos FC (1994) BmCF1, a Bombyx mon RXR-type receptor related to the Drosophila ultraspiracle. J Mol Biol 238, 479-486.
32. Jindra M, Huang JY, Malone F, Asahina M & Riddiford LM (1997) Identification and mRNA developmental profiles of two ultraspiracle isoforms in the epidermis and wings of Manduca sexta. Insect Mol Biol 6, 41-53.
33. Perera SC, Palli SR, Ladd TR, Krell PJ & Retnakaran A (1998) The ultraspiracle gene of the spruce budworm, Choristoneura fumiferana: cloning of cDNA and developmental expression of mRNA. Dev Genet 22, 169-179.
34. Henrich VC, Sliter TJ, Lubahn DB, MacIntyre A & Gilbert LI (1990) A steroid/thyroid hormone receptor superfamily member in Drosophila melanogaster that shares extensive sequence similarity with a mammalian homologue. Nucleic Acids Res 18, 4143-4148.
35. Oro AE, McKeown M & Evans RM (1990) Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor. Nature 347, 298-301.
36. Shea MJ, King DL, Conboy MJ, Mariani BD & Kafatos FC (1990) Proteins that bind to Drosophila chorion cis-regulatory elements: a new C2H2 zinc finger protein and a C2C2 steroid receptor-like component. Genes Dev 4, 1128-1140.
37. Kapitskaya M, Wang S, Cress DE, Dhadialla TS & Raikhel AS (1996) The mosquito ultraspiracle homologue, a partner of ecdysteroid receptor heterodimer: cloning and characterization of isoforms expressed during vitellogenesis. Mol Cell Endocrinol 121, 119-132.