PPARα activation potentiates AhR-induced CYP1A1 expression

Toxicology

Volumn 216, Issue 2-3, 2005, Pages 122-128

  Fallone, Frédérique ^a   Villard, Pierre Henri ^a   Decome, Laetitia ^b   Sérée, Eric ^a   Méo, Michel De ^b   Chacon, Christine ^b   Durand, Alain ^b   Barra, Yves ^a   Lacarelle, Bruno ^a  

^a CNRS   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

3 Methylcholanthrene; AhR; Human CYP1A1; Induction; PPAR ; WY14643

Indexed keywords

3 METHYLCHOLANTHRENE; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID; AHR PROTEIN, HUMAN; PYRIMIDINE DERIVATIVE;

ARTICLE; CELL STRAIN CACO 2; CONCENTRATION (PARAMETERS); ENZYME ACTIVATION; ENZYME ACTIVITY; EXPOSURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RISK ASSESSMENT; BIOSYNTHESIS; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; ENZYME INDUCTION; EVALUATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; WESTERN BLOTTING;

BLOTTING, WESTERN; CACO-2 CELLS; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; METHYLCHOLANTHRENE; PPAR ALPHA; PROMOTER REGIONS (GENETICS); PYRIMIDINES; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER;

EID: 28244484677     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2005.07.020     Document Type: Article

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