Mobilization of iron from cells by hydroxyquinoline-based chelators

Biochemical Pharmacology

Volumn 71, Issue 1-2, 2005, Pages 214-222

  Mouralian, C ^a,b   Buss, J L ^c   Stranix, B ^d   Chin, J ^e   Ponka, P ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^d INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cellular iron metabolism; Intracellular iron chelatores; Iron chelator toxicity; Oral bioavailability; Rational drug design

Indexed keywords

C1 [2,2' [ETHANE 1,2 DIYLBIS(IMINOMETHYLENE)]DIQUINOLIN 8 OL]; C2 [2,2' [CYCLOHEXANE 1,2 DIYLBIS(IMINOMETHYLENE)]DIQUINOLIN 8 OL]; IRON CHELATING AGENT; IRON COMPLEX; QUINOLINOL DERIVATIVE; TRANSFERRIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL CULTURE; CELL STRAIN K 562; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROPHILICITY; INCUBATION TIME; IRON DEPLETION; IRON KINETICS; IRON TRANSPORT; LIPOPHILICITY; PRIORITY JOURNAL; RETICULOCYTE; SYNTHESIS; TOXICITY;

CHELATING AGENTS; CYCLOHEXYLAMINES; ETHYLENEDIAMINES; HUMANS; HYDROXYQUINOLINES; IRON; K562 CELLS; RETICULOCYTES; SPECTROPHOTOMETRY;

EID: 28244435767     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.10.032     Document Type: Article

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