The inhibitory effect of glutathione on buccal enzymatic degradation of therapeutic peptides (leu-enkephalin, luteinizing hormone-releasing hormone and pituitary adenylate cyclase activating peptide)

Journal of Drug Delivery Science and Technology

Volumn 15, Issue 6, 2005, Pages 435-438

  Langoth, N ^a   Bernkop Schnurch A ^b   Kurka, P ^c  

^a Thiomatrix Forschungs und Beratungs GmbH   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c BAYER AG   (Germany)

Author keywords

Buccal route; Enzymatic barrier; Glutathione; Leu enkephalin; LHRH; PACAP

Indexed keywords

ENZYME INHIBITOR; GLUTATHIONE; GONADORELIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; LEUCINE ENKEPHALIN; MICROSOMAL AMINOPEPTIDASE; SYNTHETIC PEPTIDE;

ANIMAL TISSUE; ARTICLE; CHEEK MUCOSA; CONTROLLED STUDY; DIFFUSION CHAMBER; DRUG DEGRADATION; DRUG FORMULATION; DRUG STABILITY; ENZYMATIC DEGRADATION; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PROTEIN DEGRADATION; QUANTITATIVE ASSAY; SWINE;

EID: 28144439741     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1773-2247(05)50084-4     Document Type: Article

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