Toward the development of a lab-on-a-chip dual-function leukocyte and C-reactive protein analysis method for the assessment of inflammation and cardiac risk

Clinical Chemistry

Volumn 51, Issue 12, 2005, Pages 2391-2395

  Christodoulides, Nicolaos ^a   Floriano, Pierre N ^a   Acosta, Shelley A ^a   Ballard, Karri L Michael ^a   Weigum, Shannon E ^a   Mohanty, Sanghamitra ^a   Dharshan, Priya ^a   Romanovicz, Dwight ^a   McDevitt, John T ^a,b  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b The University of Texas at Austin   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CD45 ANTIGEN; LIPID; MICROSPHERE;

ACUTE HEART INFARCTION; ANALYTICAL EQUIPMENT; ANTIBODY LABELING; ARTICLE; ATHEROSCLEROSIS; BLOOD LEVEL; CAMERA; CARDIOVASCULAR RISK; COMPUTER PROGRAM; CONTROLLED STUDY; DATA ANALYSIS; ELECTRONICS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; INFLAMMATION; ISCHEMIC HEART DISEASE; LEUKOCYTE COUNT; MICROFLUIDICS; MORTALITY; SCANNING ELECTRON MICROSCOPY;

C-REACTIVE PROTEIN; HEART DISEASES; HUMANS; IMMUNOASSAY; INFLAMMATION; LEUKOCYTES; MICROCHIP ANALYTICAL PROCEDURES; MICROSCOPY, ELECTRON, SCANNING; RISK FACTORS;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 28044440268     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2005.054882     Document Type: Article

References (24)

1. Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997;336:973-9.
2. Rifai N, Ridker PM. High sensitivity C-reactive protein. A novel and promising marker of coronary heart disease. Curr Cardiol Rep 1999;1:99-104.
3. Ridker PM. C-Reactive protein - a simple test to help predict risk of heart attack and stroke. Circulation 2003;108:E81-5.
4. Albert MA, Glynn RJ, Ridker PM. Plasma concentration of C-reactive protein and the calculated Framingham coronary heart disease risk score. Circulation 2003;108:161-5.
5. Friedman GD, Klatsky AL, Siegelaub AB. The leukocyte count as a predictor of myocardial infarction. N Engl J Med 1974;290:1275-8.
6. Hoffman M, Blum A, Baruch R, Kaplan E, Benjamin M. Leukocytes and coronary heart disease. Atherosclerosis 2004;172:1-6.
7. Margolis KL, Manson JE, Greenland P, Rodabough RJ, Bray PF, Safford M, et al. Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women. Arch Intern Med 2005;165:500-8.
8. Furman MI, Becker RC, Yarzebski J, Savegeau J, Gore JM, Goldberg RJ. Effect of elevated leukocyte count on in-hospital mortality following acute myocardial infarction. Am J Cardiol 1996;78:945-8.
9. Furman MI, Gore JM, Anderson FA, Budaj A, Goodman SG, Avezum A, et al. Elevated leukocyte count and adverse hospital events in patients with acute-coronary syndromes: findings from the Global Registry of Acute Coronary Events (GRACE). Am Heart J 2004;147:42-8.
10. Ridker PM, Rifai N, Pfeffer MA, Sacks FM, Moye LA, Goldman S, et al. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with mean cholesterol levels. Circulation 1998;98: 839-44.
11. Yip HK, Wu CJ, Chang HW, Yang CH, Yeh KH, Chua S, et al. Levels and values of serum high-sensitivity C-reactive protein within 6 hours after the onset of acute myocardial infarction. Chest 2004;126:1417-22.
12. Grau AJ, Boddy AW, Dukovic DA, Buggle F, Lichy C, Brandt T, et al. Leukocyte count as an independent predictor of recurrent ischemic events. Stroke 2004;35:1147-52.
13. Lavigne JJ, Savoy S, Clevenger MB, Ritchie JE, McDoniel B, Yoo SJ, et al. Solution-based analysis of multiple analytes by a sensor array: toward the development of an "electronic tongue". J Am Chem Soc 1998;120:6429-30.
14. Goodey A, Lavigne JJ, Savoy SM, Rodriguez MD, Curey T, Tsao A, et al. Development of multianalyte sensor arrays composed of chemically derivatized polymeric microspheres localized in micromachined cavities. J Am Chem Soc 2001;123:2559-70.
15. Christodoulides N, Tran M, Floriano PN, Rodriguez M, Goodey A, Ali M, et al. A microchip-based multianalyte assay system for the assessment of cardiac risk. Anal Chem 2002;74:3030-36.
16. Ali MF, Kirby R, Goodey AP, Rodriguez MD, Ellington AD, Neikirk DP, et al. DNA hybridization and discrimination of single-nucleotide mismatches using chip-based microbead arrays. Anal Chem 2003;75:4732-39.
17. Wiskur SL, Floriano PN, Anslyn EV, McDevitt JT. A multicomponent sensing ensemble in solution: differentiation between structurally similar analytes. Angew Chem Int Ed Engl 2003;42:2070-72.
18. McCleskey SC, Floriano PN, Wiskur SL, Anslyn EV, McDevitt JT. Citrate and calcium determination in flavored vodkas using artificial neural networks. Tetrahedron 2003;59:10089-92.
19. Christodoulides N, Mohanty S, Miller CS, Langub MC, Floriano PN, Dharshan P, et al. Application of microchip assay system for the measurement of C-reactive protein in human saliva. Lab Chip 2004;5:261-9.
20. Floriano PN, Christodoulides N, Romanovicz DK, Bernard B, Simmons GW, Cavell M, et al. Membrane-based on-line optical analysis system for rapid detection of bacteria and spores. Biosens Bioelectron 2005;20:2079-88.
21. Rodriguez WR, Christodoulides N, Floriano PN, Graham S, Mohanty S, Dixon M, et al. A microchip CD4 counting method for HIV monitoring in resource-poor settings. PLoS Med 2005;2:e182.
22. Dalchau R, Kirkley J, Fabre JW. Monoclonal-antibody to a human leukocyte-specific membrane glycoprotein probably homologous to the leukocyte-common (L-C) antigen of the rat. Eur J Immunol 1980;10:737-44.
23. Berton G, Cordiano R, Palmieri R, Pianca S, Pagliara V, Palatini P. C-Reactive protein in acute myocardial infarction: association with heart failure. Am Heart J 2003;145:1094-1101.
24. Rasband W. Image J, image processing and analysis in Java. Bethesda, MD: National Institutes of Health, 2005.