Possible inhibition of cancer cell adhesion to the extracellular matrix in NK4-induced suppression of peritoneal implantation

Anticancer Research

Volumn 25, Issue 6 B, 2005, Pages 3847-3854

  Yoshimura, Mamoru ^a   Fujiwara, Hitoshi ^a   Kubota, Takeshi ^a   Amaike, Hisashi ^a   Takashima, Kazuhiro ^a   Inada, Satoshi ^a   Atsuji, Kiyoto ^a   Araki, Yasunobu ^a   Matsumoto, Kunio ^b   Nakamura, Toshikazu ^b   Yamagishi, Hisakazu ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

HGF; Milky spots; NK4; Peritoneal implantation

Indexed keywords

COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; RECOMBINANT SCATTER FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CELL ADHESION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; IMPLANTATION; METASTASIS; MOUSE; NONHUMAN; PERITONEUM CANCER; PRIORITY JOURNAL; TUMOR GROWTH;

ADENOCARCINOMA; ADENOVIRIDAE; ANIMALS; CELL ADHESION; CHO CELLS; COLONIC NEOPLASMS; CRICETINAE; EXTRACELLULAR MATRIX; FEMALE; GENETIC VECTORS; HEPATOCYTE GROWTH FACTOR; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; PERITONEAL NEOPLASMS; TRANSFECTION;

EID: 27944489892     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Nakamura T, Matsumoto K, Kiritoshi A, Tano Y and Nakamura T: Induction of hepatocyte growth factor in fibroblasts by tumor-derived factors affects invasive growth of tumor cells: in vitro analysis of tumor-stromal interactions. Cancer Res 57: 3305-3313, 1997.
2. Jeffers M, Rong S and Woude GF: Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis. J Mol Med 74: 505-513, 1996.
3. Fazekas K, Csuka O, Koves I, Raso E and Timar J: Experimental and clinicopathologic studies on the function of the HGF receptor in human colon cancer metastasis. Clin Exp Metastasis 18: 639-649, 2000.
4. Date K, Matsumoto K, Shimura H, Tanaka M and Nakamura T: HGF/NK4 is a specific antagonist for pleiotrophic actions of hepatocyte growth factor. FEBS Lett 420: 1-6, 1997.
5. Date K, Matsumoto K, Kuba K, Shimura H, Tanaka M and Nakamura T: Inhibition of tumor growth and invasion by a four-kringle antagonist (HGF/NK4) for hepatocyte growth factor. Oncogene 17: 3045-3054, 1998.
6. Kuba K, Matsumoto K, Date K, Shimura H, Tanaka M and Nakamura T: HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice. Cancer Res 60: 6737-6743, 2000.
7. Parr C, Hiscox S, Nakamura T, Matsumoto K and Giang WG: NK4, a new HGF/SF variant, is an antagonist to the influence of HGF/SF on the motility and invasion of colon cancer cells. Int J Cancer 85: 563-570, 2000.
8. Tomioka D, Maehara N, Kuba K, Mizumoto K, Tanaka M, Matsumoto K and Nakamura T: Inhibition of growth, invasion, and metastasis in human pancreatic carcinoma cells by NK4 in an orthotopic mouse model. Cancer Res 61: 7518-7524, 2001.
9. Kubota T, Fujiwara H, Amaike H, Takashima K, Inada S, Atsuji K, Yoshimura M, Matsumoto K, Nakamura T and Yamagishi H: Reduced HGF expression in subcutaneous CT26 tumor genetically modified to secrete NK4 and its possible relation with antitumor effects. Cancer Sci 95: 321-327, 2004.
10. Wen J, Matsumoto K, Taniura N, Tomioka D and Nakamura T: Hepatic gene expression of NK4, an HGF-antagonist/angiogenesis inhibitor, suppresses liver metastasis and invasive growth of colon cancer in mice. Cancer Gene Ther 11: 419-430, 2004.
11. Kushibiki T, Matsumoto K, Nakamura T and Tabata Y: Suppression of tumor metastasis by NK4 plasmid DNA released from cationized gelatin. Gene Ther 11: 1205-1214, 2004.
12. Fujiwara H, Kubota T, Amaike H, Inada S, Takashima K, Atsuji K, Yoshimura M, Maemondo M, Narumi K, Nukiwa K, Matsumoto K, Nakamura T, Hagiwara A and Yamagishi H: Suppression of peritoneal implantation of gastric cancer cells by adenovirus vector-mediated NK4 expression. Cancer Gene Ther 12: 206-216, 2005.
13. Saimura M, Nagai E, Mizumoto K, Maehara N, Minamishima YA, Katano M, Matsumoto K, Nakamura T and Tanaka M: Tumor suppression through angiogenesis inhibition by SUIT-2 pancreatic cancer cells genetically engineered to secrete NK4. Clin Cancer Res 10: 3243-3249, 2002.
14. Hagiwara A, Takahashi T, Sawai K, Taniguchi H, Shimotsuma M, Okano S, Sakakura C, Tsujimoto H, Osaki K, Sasaki S and Shirasu M: Milky spots as the implantation site for malignant cells in peritoneal dissemination in mice. Cancer Res 53: 687-692, 1993.
15. Tsujimoto H, Takahashi T, Hagiwara A, Shimotsuma M, Sakakura C, Osaki S, Sasaki S, Shirasu M, Sakakibara T, Ohyama T, Sakuyama A, Ohgaki M, Imanishi T and Yamasaki J: Site-specific implantation in the milky spots of malignant cells in peritoneal dissemination: immunohistochemical observation in mice inoculated intraperitoneally with bromodeoxyuridine-labelled cells. Br J Cancer 71: 468-472, 1995.
16. Liebermann-Meffert D, White H and Liebermann A: Milky spots (lymphoreticular organ). In: The Greater Omentum. Anatomy, Physiology, Pathology, Surgery with an Historical Survey. Liebermann-Meffert D, White H (eds.). Berlin, Heidelberg, New York, Springer-Verlag, pp. 46-56, 1983.
17. Seki T, Ihara I, Sugimura A, Shimonishi M, Nishizawa T, Asami O, Hagiya M, Nakamura T and Shimizu S: Isolation and expression of cDNA for different forms of hepatocyte growth factor from human leukocyte. Biochem Biophys Res Commun 172: 321-327, 1990.
18. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, Tashiro K and Shimizu S: Molecular cloning and expression of human hepatocyte growth factor. Nature 342: 440-443, 1989.
19. Corbett TH, Griswold DP Jr, Roberts BJ, Peckham JC and Schabel FM Jr: Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res 35: 2434-2439, 1975.
20. Ishiyama M, Miyazono Y, Sasamoto K, Ohkura Y and Ueno K: A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability. Talanta 44: 1299-1305, 1997.
21. Leighton J, Kalla RL, Kline I and Belkin M: Pathogenesis of tumor invasion. 1. Interaction between normal tissues and "transformed" cells in tissue culture. Cancer Res 19: 23-27, 1959.
22. Ogiu T and Nakamura K: Growth of intraperitoneally transplanted ascites hepatoma, AH39 cells, in the area of gelatin sponge inoculation into the abdominal wall of Donryu rats. Jpn J Cancer Res 70: 173-179, 1979.
23. Yashiro M, Chung YS, Inoue T, Nishimura S, Matsuoka T, Fujihara T and Sowa M: Hepatocyte growth factor (HGF) produced by peritoneal fibroblasts may affect mesothelial cell morphology and promote peritoneal dissemination. Int J Cancer 67: 289-293, 1996.
24. Trusolino L, Cavassa S, Angelini P, Ando M, Bertotti A, Comoglio PM and Boccaccio C: HGF/scatter factor selectively promotes cell invasion by increasing integrin avidity. FASEB J 14: 1629-1640, 2000.
25. Beviglia L and Kramer RH: HGF induces FAK activation and integrin-mediated adhesion in MTLn3 breast carcinoma cells. Int J Cancer 83: 640-649, 1999.
26. Weimar IS, de Jong D, Muller EJ, Nakamura T, van Gorp JM, de Gast GC and Gerritsen WR: Hepatocyte growth factor/scatter factor promotes adhesion of lymphoma cells to extracellular matrix molecules via alpha 4 beta 1 and alpha 5 beta 1 integrins. Blood 89: 990-1000, 1997.
27. Hynes RO: Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69: 11-25, 1992.
28. Burridge K, Turner CE and Romer LH: Tyrosine phosphorylation of paxillin and pp!25FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J Cell Biol 119: 893-903, 1992.
29. Matsumoto K, Matsumoto K, Nakamura T and Kramer RH: Hepatocyte growth factor / scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125 FAK) and promotes migration and invasion by oral squamous cell carcinoma cells. J Biol Chem 269: 31807-31813, 1994.
30. Heel KA and Hall JC: Peritoneal defenses and peritoneum-associated lymphoid tissues. Br J Surg 83: 1031-1036, 1996.