Hepatic gene expression of NK4, an HGF-antagonist/angiogenesis inhibitor, suppresses liver metastasis and invasive growth of colon cancer in mice

Cancer Gene Therapy

Volumn 11, Issue 6, 2004, Pages 419-430

  Wen, Jinhua ^a   Matsumoto, Kunio ^a   Taniura, Naoko ^a   Tomioka, Daisaku ^a   Nakamura, Toshikazu ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

c Met; Colon cancer; HGF; Liver metastasis; NK4; Tumor angiogenesis

Indexed keywords

ANGIOGENESIS INHIBITOR; GENE PRODUCT; NK4 PROTEIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER INVASION; CANCER MORTALITY; CANCER SURVIVAL; COLON CANCER; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GENE; GENE EXPRESSION; HYDRODYNAMICS; LIVER METASTASIS; LIVER NODULE; MALE; METASTASIS INHIBITION; MOUSE; NK4 GENE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PLASMID; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANGIOGENESIS INHIBITORS; ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CHO CELLS; COLONIC NEOPLASMS; CRICETINAE; CULTURE MEDIA, CONDITIONED; GENE TRANSFER TECHNIQUES; HEPATOCYTE GROWTH FACTOR; HUMANS; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; LIVER; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MITOGENS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PLASMIDS; PROTO-ONCOGENE PROTEINS C-MET; RECOMBINANT PROTEINS; TIME FACTORS; TRANSGENES;

ANIMALIA; MURINAE;

EID: 2942555478     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700705     Document Type: Article

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