Influence of mitotic delay on the results of biological dosimetry for high doses of ionizing radiation

Radiation and Environmental Biophysics

Volumn 44, Issue 3, 2005, Pages 211-218

  Heimers, A ^a   Brede, H J ^b   Giesen, U ^b   Hoffmann, W ^c  

^a UNIVERSITY OF BREMEN   (Germany)

^b PHYSIKALISCH TECHNISCHE BUNDESANSTALT   (Germany)

^c UNIVERSITY MEDICINE GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ABERRATIONS; CHROMOSOMES; IONIZING RADIATION; NEUTRONS; SAMPLING; X RAY ANALYSIS;

BLOOD SAMPLES; CENTRIC RING CHROMOSOMES; MITOTIC DELAY; SHORT-TERM CULTURES;

DOSIMETRY;

ADULT; ARTICLE; BLOOD SAMPLING; CHROMOSOME ABERRATION; CONTROLLED STUDY; DICENTRIC CHROMOSOME; DOSIMETRY; HUMAN; HUMAN CELL; IONIZING RADIATION; LYMPHOCYTE CULTURE; LYMPHOCYTE PROLIFERATION; MALE; METAPHASE CHROMOSOME; MITOSIS INHIBITION; NEUTRON RADIATION; NORMAL HUMAN; RADIATION DOSE; RADIATION EXPOSURE; RING CHROMOSOME; X RAY;

ADULT; BIOLOGICAL ASSAY; CELL PROLIFERATION; CELLS, CULTURED; CHROMOSOME ABERRATIONS; CHROMOSOMES; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; MITOSIS; NEUTRONS; RADIATION DOSAGE; RADIOMETRY; RELATIVE BIOLOGICAL EFFECTIVENESS; TIME FACTORS; X-RAYS;

EID: 27944482438     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00411-005-0014-3     Document Type: Article

References (41)

1. Bender MA, Awa AA, Brooks AL, Evans HJ, Groer PG, Littlefield LG, Pereira C, Preston RJ, Wachholz BW (1988) Current status of cytogenetic procedures to detect and quantify previous exposures to radiation. Mutat Res 196:103-159
2. Bauchinger M (1995) Quantification of low-level radiation exposure by conventional chromosome aberration analysis. Mutat Res 339:177-189
3. Hoffmann W, Schmitz-Feuerhake I (1999) How radiation-specific is the dicentric assay? J Exp Anal Environ Epidemiol 2:113-133
4. Schröder H, Heimers A (2002) Chromosome aberrations induced in human lymphocytes by in vitro and in vivo X-rays. Mutat Res 517:167-172
5. LLoyd DC, Dolphin GW, Purrott RJ, Tipper PA (1977) The effect of X-ray induced mitotic delay on chromosome aberration yields in human lymphocytes. Mutat Res 42:401-412
6. Scholz M, Kraft-Weyrather W, Ritter S, Kraft G (1994) Cell cycle delays by heavy ion irradiation of synchronous mammalian cells. Int J Radiat Biol 66:59-75
7. Ritter S, Nasonova E, Kraft-Weyrather W, Kraft G (1994) Influence of radiation quality on the expression of chromosomal damage. Int J Radiat Biol 66:625-628
8. Ritter S, Nasonova E, Furusawa Y, Ando K (2002) Relationship between aberration yield and mitotic delay in human lymphocytes exposed to 200 MeV/u Fe-ions or X-rays. J Radiat Res 43:S175-S179
9. Nasonova E, Ritter S (2004) Cytogenetic effects of densely ionising radiation in human lymphocytes: impact of cell cycle delays. Cytogenet. Genome Res 104:216-220
10. 1 V79 cells. Int J Radiat Biol 69:155-166
11. Anderson RM, Marsden SJ, Wright EG, Kadhim MA, Goodhead DT, Griffin CS (2000) Complex chromosome aberrations in peripheral blood lymphocytes as a potential biomarker of exposure to high-LET α-particles. Int J Radiat Biol 76:31-42
12. Brede HJ, Cosack M, Dietze G, Gumpert H, Guldbakke S, Jahr R, Kutscha M, Schlegel-Bickmann D, Schölermann H (1980) The Braunschweig accelerator facility for fast neutrons research I Building design and accelerators. Nucl Instrum Methods 169:349-358
13. Dietze G, Brede HJ. Schlegel-Bickmann D (1984) Dosimetry for neutron therapy at the Physikalisch-Technische Bundesanstalt (PTB). In: advances in dosimetry for fast neutrons and heavy charged particles for therapy applications, IAEA-Report-AG-371/14, pp 203-215
14. Brede HJ (2004) Darstellung der Wasserenergiedosis im kollimierten, gemischten Neutronen-Photonenfeld der PTB. PTB-Bericht: PTB-N-45, pp 170-179
15. 9Be(d,n) thick-target neutron spectra for deuteron energies between 2.6 and 7.0 MeV. Nucl Instrum Methods A324:239-246
16. Waterman FM, Kuchnir FT, Skaggs LS, Kouzes RT, Moore WH (1979) Energy dependence of the neutron sensitivity of C-Co2, Mg-Ar and TE-TE ionisation chambers. Phys Med Biol 24:721-733
17. Caswell RS, Coyne JJ, Randolph ML (1980) Kerma factors for neutron energies below 30 MeV. Radiat Res 83:217-254
18. Heimers A, Schröder H, Lengfelder E, Schmitz-Feuerhake I (1995) Chromosome aberration analysis in aircrew members. Radiat Prot Dosimetry 60:171-175
19. Perry P, Wolff S (1974) New Giemsa method for the differential staining of sister chromatids. Nature 251:156-158
20. Hoffmann W, Dannheim T, Grell-Büchtmann I, Heimers A, Nahrmann A, Schröder H, Schmitz-Feuerhake I, Tomalik P (1991) Quantitative Chromosomenaberrationsanalyse zur retrospektiven Dosisermittlung nach Exposition mit ionisierender Strahlung: Biologische Dosimetrie. BIOforum 14:381-385
21. Mitelmann F (ed) (1995) [ISCN. An international system for human cytogenetic nomenclature]., Basel, Karger
22. Radakrishna RC, Chakravarti J (1956) Some small sample tests of significance for a Poisson distribution. Biometrics 12:264-282
23. Savage JRK (1970) Sites of radiation induced chromosome exchanges. Curr Top Radiat Res 6:89-100
24. Edwards AA, Lloyd DC, Purrott RJ (1979) Radiation induced chromosome aberrations and the Poisson distribution. Radiat Environ Biophys 16:89-100
25. Bender MA, Brewen JG (1969) Factors influencing chromosome aberration yields in the human peripheral leucocyte system. Mutat Res 8:383-399
26. 0 stage of the cell cycle of early as compared to late replicating cells. Hum Genet 35:57-70
27. 0. Int J Radiat Biol 78:765-772
28. Boei JJWA, Vermeulen S, Natarajan AT (1996) Detection of chromosomal aberrations by fluorescence in situ hybridization in the first three postirradiation divisions of human lymphocytes. Mutat Res 349:127-135
29. Guerrero-Carbajal YC, Moquet JE, Edwards AA, Lloyd DC (1998) The persistence of FISH translocations for retrospective biological dosimetry after simulated whole or partial body irradiation. Radiat Prot Dosim 76:159-168
30. Krishnaja AP, Sharma NK (2004) Transmission of γ-ray-induced unstable chromosome aberrations through successive mitotic divisions in human lymphocytes in vitro. Mutagenesis 19:299-305
31. Leonard A, Decat G (1979) Relation between cell cycle and yield of aberrations observed in irradiated human lymphocytes. Can. J Genet Cytol 21:473-478
32. Scott D, Lyons CY (1979) Homogeneous sensitivity of human peripheral blood lymphocytes to radiation-induced chromosome damage. Nature 278:756-758
33. Buul v PPW. Natarajan AT (1980) Chromosomal radiosensitivity of human leucocytes in relation to sampling time. Mutat Res 70:61-69
34. George K, Wu H, Willingham V, Furusawa Y, Kawata T, Cucinotta FA (2001) High- and low-LET induced chromosome damage in human lymphocytes: a time-course of aberrations in metaphase and interphase. Int J Radiat Biol 77:175-183
35. Durante M, Yamada S, Ando K, Furusawa Y, Kawata T, Majima H, Nakano T, Tsujii H (1999) Measurements of the equivalent whole-body dose during radiation therapy by cytogenetic methods. Phys Med Biol 44:1289-1298
36. Peak MJ, Wang L, Hill CK, Peak JG (1991) Comparison of repair of DNA double strand breaks caused by neutron or gamma radiation in cultured human cells. Int J Radiat Biol 60:891-898
37. Loucas BD, Geard CR (1994) Kinetics of chromosome rejoining in normal human fibroblasts after exposure to low-and high-LET radiations. Radiat Res 138:352-360
38. International Commission on Radiation Units and Measurements Inc. ICRU (1970) Linear Energy Transfer. ICRU Report 16. Bethesda, Maryland, USA
39. 238Pu α-particles and detected by fluorescence in situ hybridization using single chromosome-specific probes. Int J Radiat Biol 67:431-439
40. Hahnfeldt P, Hlatky LR, Brenner DJ, Sachs RK (1995) Chromosome aberrations produced by radiation: the relationship between excess acentric fragments and dicentrics. Radiat Res 141:136-152
41. Lloyd DC, Edwards AA, Prosser JS (1986) Chromosome aberrations induced in human lymphocytes by in vitro acute X and gamma radiation. Radiat Prot Dosimetry 15:83-88