Autoantibodies to opsonins of apoptotic cells in systemic lupus erythematosus

Annals of the Rheumatic Diseases

Volumn 64, Issue 12, 2005, Pages 1669-1670

  Limburg, P C ^a   Bijl, M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID P COMPONENT; AUTOANTIBODY; OPSONIN; PROTEIN ANTIBODY;

APOPTOSIS; AUTOIMMUNITY; CONTROLLED STUDY; CORRELATION ANALYSIS; EDITORIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; NONHUMAN; OPSONIZATION; PATHOPHYSIOLOGY; PHAGOCYTOSIS; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

APOPTOSIS; AUTOANTIBODIES; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; OPSONIN PROTEINS; PHAGOCYTOSIS; SERUM AMYLOID P-COMPONENT;

EID: 27944481645     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2005.043505     Document Type: Editorial

References (16)

1. Casciola-Rosen LA, Anhalt G, Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994;179:1317-30.
2. Manderson AP, Botto M, Walport MJ. The role of complement in the development of systemic lupus erythematosus. Annu Rev Immunol 2004;22:431-56.
3. Garlanda C, Bottazzi B, Bastone A, Mantovani A. Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. Annu Rev Immunol 2005;23:337-66.
4. Familian A, Zwart B, Huisman HG, Rensink I, Roem D, Hordijk PL, et al. Chromatin-independent binding of serum amyloid P component to apoptotic cells. J Immunol 2001;167:647-54.
5. Bijl M, Horst G, Bijzet J, Bootsma H, Limburg PC, Kallenberg CGM. Serum amyloid P component binds to late apoptotic cells and mediates their uptake by monocyte-derived macrophages. Arthritis Rheum 2003;48:248-54.
6. Van Rossum AP, Fazzini F, Limburg PC, Manfredi AA, Rovere-Querini P, Mantovani, et al. The protolypic tissue pentraxin PTX3, in contrast to the short pentraxin serum amyloid P, inhibits phagocytosis of late apoptotic neutrophils by macrophages. Arthritis Rheum 2004;50:2667-74.
7. Hart SP, Smith JR, Dransfield I. Phagocytosis of opsonized apoptotic cells: roles for 'old-fashioned' receptors for antibody and complement. Clin Exp Immunol 2004;135:181-5.
8. Gaipl US, Brunner J, Beyer TD, Voll RE, Kalden JR, Herrmann M. Disposal of dying cells: a balancing act between infection and autoimmunity. Arthritis Rheum 2003;48:6-11.
9. Botto M, Dell'Agnola C, Bygrave AE, Thompson EM, Cook HT, Petry F, et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 1998;19:56-9.
10. Bickerstaff MCM, Botto M, Hutchinson WL, Herbert J, Tennent GA, Bybee A, et al. Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity. Nat Med 1999;5:694-7.
11. Gillmore JD, Hutchinson WL, Herbert J, Bybee A, Mitchell A, Hasseriian RP, et al. Autoimmunity and glomerulonephritis in mice with targeted deletion of the serum amyloid P component gene: SAP deficiency or strain combination? Immunology 2004;112:255-64.
12. Trouw LA, Groeneveld TWL, Seelen MA, Duijs JMGJ, Bajema IM, Prins FA, et al. Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes. J Clin Invest 2004;114:679-88.
13. Marai I, Tincani A, Balestieri G, Shoenfeld Y. Anticardiolipin and anti-beta-2-glycoprotein I antibodies. Autoimmunity 2005;38:33-8.
14. Kaburaki J, Kuwana M, Yamamoto M, Kawi S, Ikeda Y. Clinical significance of anti-annexin V antibodies in patients with systemic lupus erythematosus. Am J Hematol 1997;54:209-13.
15. Sjöwall C, Eriksson P, Almer S, Skogh T. Autoantibodies to C-reactive protein is a common finding in SLE, but not in primary Sjögren's syndrome, rheumatoid arthritis, or inflammatory bowel syndrome. J Autoimmun 2002;19:155-60.
16. Zandman-Goddard G, Blank M, Langevitz P, Slutsky L, Pras M, Levy Y, et al. Anti-serum amyloid component P antibodies in patients with systemic lupus erythematosus correlate with disease activity. Ann Rheum Dis 2005;64:1698-1702.