Autoantibodies to C-reactive protein is a common finding in SLE, but not in primary Sjögren's syndrome, rheumatoid arthritis or inflammatory bowel disease

Journal of Autoimmunity

Volumn 19, Issue 3, 2002, Pages 155-160

  Sjöwall, Christopher ^a   Eriksson, Per ^a   Almer, Sven ^a   Skogh, Thomas ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Autoantibodies; C reactive protein; Rheumatoid arthritis; Sj gren's syndrome; Systemic lupus erythematosus

Indexed keywords

AUTOANTIBODY; C REACTIVE PROTEIN; DNA ANTIBODY; DOUBLE STRANDED DNA; PROTEIN ANTIBODY;

ADULT; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; AUTOIMMUNE HEPATITIS; AUTOIMMUNITY; BLOOD ANALYSIS; CELL ADHESION; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; ULCERATIVE COLITIS; ANIMAL; ANTIBODY SPECIFICITY; ENTERITIS; IMMUNOLOGY; MIDDLE AGED; RABBIT;

ADULT; ANIMALS; ANTIBODY SPECIFICITY; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; C-REACTIVE PROTEIN; FEMALE; HUMANS; INFLAMMATORY BOWEL DISEASES; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; RABBITS; SJOGREN'S SYNDROME;

EID: 0036850577     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.2002.0608     Document Type: Article

References (36)

1. Du Clos T.W. 2000. Function of C-reactive protein. Ann. Med. 32: 274-278
2. Gewurz H., Zhang X.H., Lint T.F. 1995. Structure and function of the pentraxins. Curr. Opin. Immunol. 7: 54-64
3. Potempa L.A., Maldonado B.A., Laurent P., Zemel E.S., Gewurz H. 1983. Antigenic, electrophoretic and binding alterations of human C-reactive protein modified selectively in the absence of calcium. Mol. Immunol. 20: 1165-1175
4. Kresl J.J., Potempa L.A., Anderson B.E. 1998. Conversion of native oligomeric to a modified monomeric form of human C-reactive protein. Int. J. Biochem. Cell Biol. 30: 1415-1426
5. Zouki C., Haas B., Chan J.S., Potempa L.A., Filep J.G. 2001. Loss of pentameric symmetry of C-reactive protein is associated with promotion of neutrophil-endothelial cell adhesion. J. Immunol. 167: 5355-5361
6. Potempa L.A., Motie M., Wright K.E., Crump B.L., Radosevich J.A., Sakai N., Lai G., Tanaka K., Kojima E., Tsuboi A., Hua L.G. 1996. Stimulation of megakaryocytopoiesis in mice by human modified C-reactive protein (mCRP). Exp. Hematol. 24: 258-264
7. Motie M., Brockmeier S., Potempa LA. 1996. Binding of model soluble immune complexes to modified C-reactive protein. J. Immunol. 156: 4435-4441
8. Stein M.P., Mold C., Du Clos T.W. 2000. C-reactive protein binding to murine leukocytes requires Fc gamma receptors. J. Immunol. 164: 1514-1520
9. Zeller J.M., Sullivan B.L. 1992. C-reactive protein selectively enhances the intracellular generation of reactive oxygen products by IgG-stimulated monocytes and neutrophils. J. Leukoc. Biol. 52: 449-455
10. Bharadwaj D., Stein M.P., Volzer M., Mold C., Du Clos T.W. 1999. The major receptor for C-reactive protein on leukocytes is FcγReceptorII. J. Exp. Med. 190: 585-590
11. Mold C., Gewurz H., Du Clos T.W. 1999. Regulation of complement activation by C-reactive protein. Immunopharmacology 42: 23-30
12. Berman S., Gewurz H., Mold C. 1986. Binding of C-reactive protein to nucleated cells leads to complement activation without cytolysis. J. Immunol. 136: 1354-1359
13. Volanakis J.E., Wirtz K.W. 1979. Interaction of C-reactive protein with artificial phosphatidylcholine bilayers. Nature 281: 155-157
14. Salonen E.M., Vartio T., Hedman K., Vaheri A. 1984. Binding of fibronectin by the acute phase reactant C-reactive protein. J. Biol. Chem. 259: 1496-1501
15. Tilett W.S., Francis T. Jr. 1930. Serological reactions in pneumonia with non-protein somatic fraction of pneumococcus. J. Exp. Med. 52: 561-571
16. Robey F.A., Jones K.D., Tanaka T., Liu T.Y. 1984. Binding of C-reactive protein to chromatin and nucleosome core particles. A possible physiological role of C-reactive protein. J. Biol. Chem. 259: 7311-7316
17. Du Clos T.W., Zlock L.T., Rubin R.L. 1988. Analysis of the binding of C-reactive protein to histones and chromatin. J. Immunol. 141: 4266-4270
18. Pepys M.B., Booth S.E., Tennent G.A., Butler P.J.G., Williams D.G. 1994. Binding of pentraxins to different nuclear structures: C-reactive protein binds to small ribonucleoprotein particles, serum amyloid P component binds chromatin and nucleoli. Clin. Exp. Immunol. 97: 152-157
19. Du Clos T.W., Mold C., Stump R.F. 1990. Identification of a polypeptide sequence that mediates nuclear localization of the acute phase protein C-reactive protein. J. Immunol. 145: 3869-3875
20. Mallya R.K., de Beer F.C., Berry H., Hamilton E.D., Mace B.E., Pepys M.B. 1982. Correlation of clinical parameters of disease activity in rheumatoid arthritis with serum concentration of C-reactive protein and erythrocyte sedimentation rate. J. Rheumatol. 9: 224-228
21. Becker G.J., Waldburger M., Hughes G.R.V., Pepys M.B. 1980. Value of serum C-reactive protein measurement in the investgation of fever in systemic lupus erythematosus. Ann. Rheum. Dis. 39: 50-52
22. Fagan E.A., Dyck R.F., Maton P.N., Hodgson H.J., Chadwick V.S., Petrie A., Pepys M.B. 1982. Serum levels of C-reactive protein in Crohn's disease and ulcerative colitis. Eur. J. Clin. Invest. 12: 351-359
23. Hind C.R.K., Ng S.C., Feng P.H., Pepys M.B. 1985. Serum C-reactive protein measurement in the detection of intercurrent infection in Oriental patients with systemic lupus erythematosus. Ann. Rheum. Dis. 44: 260-261
24. ter Borg E.J., Horst G., Limburg P.C., van Rijswijk M.H., Kallenberg C.G.M. 1990. C-reactive protein levels during disease exacerbations and infections in systemic lupus erythematosus: A prospective longitudinal study. J. Rheumatol. 17: 1642-1648
25. Robey F.A., Jones K.D., Steinberg A.D. 1985. C-reactive protein mediates the solubilization of nuclear DNA by complement in vitro. J. Exp. Med. 161: 1344-1356
26. Bell S.A., Du Clos T.W., Khursigara G., Picazo J.J., Rubin R.L. 1995. Autoantibodies to cryptic epitopes of C-reactive protein and other acute phase proteins in the toxic oil syndrome. J. Autoimmun. 8: 293-303
27. Bell S.A., Faust H., Schmid A., Meurer M. 1998. Autoantibodies to C-reactive protein (CRP) and other acute-phase proteins in systemic autoimmune diseases. Clin. Exp. Immunol. 113: 327-332
28. Vitali C., Bombardieri S., Moutsopoulos H.M., Balestrieri G., Bencivelli W., Bernstein R.M., Bjerrum K.B., Braga S., Coll J., de Vita S. 1993. Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European Community. Arthritis Rheum. 36: 340-347
29. Arnett F.C., Edworthy S.M., Bloch D.A., McShane D.J., Fries J.F., Cooper N.S., Healey L.A., Kaplan S.R., Liang M.H., Luthra H.S. 1988. The American Rheumatism Association 1987 Revised Criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31: 315-324
30. Lockhart-Mummery H.E., Morson B.C. 1960. Crohn's disease (regional enteritis) of the large intestine and its distinction from ulcerative colitis. Gut 1: 87-105
31. Mohan C., Adams S., Stanik V., Datta S.K. 1993. Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus. J. Exp. Med. 177: 1367-1381
32. Gershov D., Kim S., Brot N., Elkon K.B. 2000. C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an anti-inflammatory innate immune response: Implications for systemic autoimmunity. J. Exp. Med. 192: 1353-1364
33. Burlingame R.W., Volzer M.A., Harris J., Du Clos T.W. 1996. The effect of acute phase proteins on clearance of chromatin from the circulation of normal mice. J. Immunol. 156: 4783-4788
34. 1 mice treated with C-reactive protein. Clin. Immunol. Immunopathol. 70: 22-27
35. Bickerstaff M.C., Botto M., Hutchinson W.L., Herbert J., Tennent G.A., Bybee A., Mitchell D.A., Cook H.T., Butler P.J., Walport M.J., Pepys M.B. 1999. Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity. Nat. Med. 5: 694-697
36. Sturfelt G., Bengtsson A., Klint C., Nived O., Sjöholm A., Truedsson L. 2000. Novel roles of complement in systemic lupus erythematosus - Hypothesis for a pathogenetic vicious circle. J. Rheumatol. 27: 661-663