Elevated level of the circulating interleukin-12 in systemic lupus erythematosus

Revmatologiia

Volumn 13, Issue 3, 2005, Pages 79-82

  Ivanova, Mariana ^a   Manolova, I ^b   Stoilov, R ^b  

^a University Hospital Stara Zagora   (Bulgaria)

^b NONE

Author keywords

IL 12; Systemic lupus erythematosus; Th cell cytokines

Indexed keywords

ANTINUCLEAR ANTIBODY; COMPLEMENT COMPONENT C4; CYTOKINE; INTERLEUKIN 12;

ANTIBODY TITER; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; COMPLEMENT SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HELPER CELL; HUMAN; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE SUBPOPULATION;

EID: 27944475542     PISSN: 13100505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Amital, H. et Y. Shoenfeld. Autoimmunity and autoimmune diseases such as systemic lupus erythematosus. - In: Systemic Lupus Erythematosus. Lahita R. G. (Ed.)., N. Y., Acad. Press, 1999, 1-11.
2. Bombardier, C. et al, The Committee on Prognosis Studies in SLE. Derivation of the SLEDAI: a disease activity index for lupus patients. - Arthritis Rheum., 35, 1992, 630-640.
3. Capper, E. R. et al. Interleukin (IL)-10, IL-1ra and IL-12 profiles in active and quiescent systemic lupus erythematosus: could longitudinal studies reveal patient subgroup of differing pathology? - Clin. Exp. Immunol., 138, 2004, No 2, 348-356.
4. De Waal Malefyt, R. et al. Interleukin-10. - Curr. Opin. Immunol., 4, 1992, 314-320.
5. Dinarello, C. A. Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. - Ann. N. Y. Acad. Sci., 856, 1998, 1-11.
6. Dinarello, C. A. Role of pro- and anti-inflammatory cytokines during inflammation: experimental and clinical findings. - J. Biol. Regul. Homeost. Agents, 11, 1997, 91-103.
7. Fanauchi, M. et al. Decreased Th1-like and increased Th2-like cells in systemic lupus erythematosus. - Scand. J. Rheumatol., 27, 1998, 219-224.
8. Fehniger, T. A. et al. Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implication for the innate immune response. - J. Immunol., 162, 1999, 4511-4520.
9. Funauchi, M. et al. Decreased Th1- and increased Th2-like cells in systemic lupus erythematosus. - Scand. J. Rheumatol., 27, 1998, 219-224.
10. Gomez, D. et al. Th1/Th2 cytokines in patients with systemic lupus erythematosus: is TNF-α protective? - Semin. Arthritis Rheum., 33, 2004, No 6, 404-413.
11. Hagiwara, E. et al. Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10: Interferon gamma secreting cells in peripheral blood. - Arthritis Rheum., 39, 1996, 379-385.
12. Horwitz, D. A. et al. Decreased production of interleukin-12 and other Th 1-type cytokines in patients with recent-onset systemic lupus erythematosus. - Arthritis Rheum., 41, 1998, 838-844.
13. Horwitz, D. A. et C. Jacob. The cytokine network in the pathogenesis of systemic lupus erythematosus and possible therapeutic implications. - Springer Semin. Immunopathol., 16, 1994, 181-200.
14. Horwitz, D. A., W. Stohl et J. D. Gray. T lymphocytes, natural killer cells, cytokines and immune regulation. - In: Dubois. Lupus Erythematosus. D. J. Wallace et B. H. Hahn (Eds). Baltimore, Williams and Wilkins, 1997, 155-194.
15. Houssiau, F. A. et al. Serum interleukin-10 titers in systemic lupus erythematosus reflect disease activity. - Lupus, 4, 1995, 393-395.
16. Lee, S. M. et al. The regulation and biological activity of interleukin-12. - Leuk. Lymphoma, 29, 1998, 427.
17. Lui, T. F. et B. M. Jones. Impaired production of IL-12 in systemic lupus erythematosus.II. IL-12 production in vitro I correlated negatively with serum IL-10, positively with serum IFN gamma and negatively with disease activity in SLE. - Cytokine, 10, 1998, 148-153.
18. Lui, T. F. et B. M. Jones. Impaired production of IL-12 in systemic lupus erythematosus. I. Excessive production of IL-10 suppressed production of IL-12 by monocytes. - Cytokine, 10, 1998, 140-147.
19. Manolova, I., M. Dancheva et K. Halacheva. Predominance of IgG1 and IgG3 subclasses of antibodies to neutrophil cytoplasmic antigens in patients with systemic lupus erythematosus. - Rheum. Int., 21, 2002, 227-233.
20. Mohan, C. et al. Nucleosome. A major immunogen for pathogenic autoantibody-indusing T cells of lupus. - J. Exp. Med., 177, 1993, 1367-1381.
21. Mosmann, T. R. et S. Sad. The expanding universe of T-cell subsets: Th1, Th2 and more. - Immunol. Today, 17, 1996, 138-146.
22. Park, M. C., Y. B. Park et S. K. Lee. Elevated interleukin-18 levels correlated with disease activity in systemic lupus erythematosus. - Clin. Rheumatol., 23, 2004, 225-229.
23. Park, Y. B. et al. Elevated interleukin-10 levels correlated with disease activity in systemic lupus erythematosus. - Clin. Exp. Rheumatol., 16, 1998, 283-288.
24. Peng, S. L., J. Moslehi et J. Craft. Roles of interferon gamma and interleukin-4 in murine lupus. - J. Clin. Invest., 99, 1997, 1936-1946.
25. Robak, E. et al. Proinflammatory interferon gamma - inducing monokines (interleukin-12, interleukin-18, interleukin-15) - serum profile in patients with systemic lupus erythematosus. - Eur. Cytokine Network, 13, 2002, No 3, 364-368.
26. Segal, R. et al. Kinetics of cytokine production in experimental systemic lupus erythematosus: involvement of T helper cell 1/T helper cell 2-type cytokines in disease. - J. Immunol., 158, 1997, 3009-3016.
27. Spadaro, A., R. Scrivo et T. Rinaldi. The role of IL-12 in immune-mediated rheumatic diseases. - Reumatismo, 54, 2002, No 2, 113-121.
28. Tan, E. M. et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. - Arthritis Rheum., 25, 1982, 1271-1277.
29. Theofilopoulos, A. N. et al. The role of IFN gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity. - Arthritis Res., 3, 2001, 136.
30. Tokano, Y. et al. Levels of IL-12 in the sera of patients with systemic lupus erythematosus. (SLE) - relation to Th1- and Th2-derived cytokines. - Clin. Exp. Immunol., 116, 1999, 169-173.
31. Trinchieri, G. Immunobiology of interleukin-12. - Immunol. Res., 17, 1998, 269-278.
32. Viallard, J. F. et al. Th1 (IL-2, interferon gamma (IFN gamma) and Th2 (II-10, II-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE). - Clin. Exp. Immunol., 115, 1999, 189-195.
33. Wong, C. K. et al. Evaluation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus. - Lupus, 9, 2000, 589.
34. Wong, C. K. et al. Evaluation of plasma interleukin-18 concentration is correlated with disease activity in systemic lupus erythematosus. - Rheumatol., 39, 2000, 1078-1081.