메뉴 건너뛰기




Volumn 16, Issue 8, 2005, Pages 635-642

An ionotropic but not a metabotropic glutamate agonist potentiates the pharmacological effects of olanzapine in the rat

Author keywords

2 chloro 5 hydroxyphenylglycine; D cycloserine; Dopamine mediated behaviors; Metabotropic glutamate receptor 5; N methyl D aspartate receptors; Olanzapine; Rat; Serotonin mediated behaviors

Indexed keywords

2 CHLORO 5 HYDROXYPHENYGLYCINE; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; ATYPICAL ANTIPSYCHOTIC AGENT; CYCLOSERINE; DOPAMINE 1 RECEPTOR STIMULATING AGENT; DOPAMINE 2 RECEPTOR STIMULATING AGENT; GLYCINE; IONOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR AGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; OLANZAPINE; QUINPIROLE; SEROTONIN 2A AGONIST; UNCLASSIFIED DRUG;

EID: 27944469991     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008877-200512000-00006     Document Type: Article
Times cited : (2)

References (52)
  • 2
    • 0032007608 scopus 로고    scopus 로고
    • Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
    • Arnt J, Skarsfeldt T (1998). Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence. Neuropharmacology 18:64-101.
    • (1998) Neuropharmacology , vol.18 , pp. 64-101
    • Arnt, J.1    Skarsfeldt, T.2
  • 3
    • 0034332480 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
    • Awad H, Hubert GW, Smith Y, Levey AI, Conn PJ (2000). Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J Neurosci 20:7871-7879.
    • (2000) J Neurosci , vol.20 , pp. 7871-7879
    • Awad, H.1    Hubert, G.W.2    Smith, Y.3    Levey, A.I.4    Conn, P.J.5
  • 5
    • 0028177163 scopus 로고
    • Effects of D-cycloserine and (+)HA-966 on the locomotor stimulation induced by NMDA antagonists and clonidine in monoamine-depleted mice
    • Carlsson M, Engberg G, Carlsson A (1994). Effects of D-cycloserine and (+)HA-966 on the locomotor stimulation induced by NMDA antagonists and clonidine in monoamine-depleted mice. J Neural Transm Gen Sect 95:223-233.
    • (1994) J Neural Transm Gen Sect , vol.95 , pp. 223-233
    • Carlsson, M.1    Engberg, G.2    Carlsson, A.3
  • 6
    • 0030943091 scopus 로고    scopus 로고
    • Neurotransmitter aberrations in schizophrenia: New perspectives and therapeutic implications
    • Carlsson M, Hansson LO, Waters N, Carlsson ML (1997). Neurotransmitter aberrations in schizophrenia: new perspectives and therapeutic implications. Life Sci 61:75-94.
    • (1997) Life Sci , vol.61 , pp. 75-94
    • Carlsson, M.1    Hansson, L.O.2    Waters, N.3    Carlsson, M.L.4
  • 8
    • 0028174008 scopus 로고
    • D-Cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: An open-study
    • Cascella NG, Macciardi F, Cavallini C, Smeraldi E (1994). D-Cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-study. J Neural Transm Gen Sect 95:105-111.
    • (1994) J Neural Transm Gen Sect , vol.95 , pp. 105-111
    • Cascella, N.G.1    Macciardi, F.2    Cavallini, C.3    Smeraldi, E.4
  • 9
    • 0025228762 scopus 로고
    • D-serine antagonized phencyclidine- And MK801-induced stereotyped behavior and ataxia
    • Contreras PC (1990). D-serine antagonized phencyclidine- and MK801-induced stereotyped behavior and ataxia. Neuropharmacology 29:291-293.
    • (1990) Neuropharmacology , vol.29 , pp. 291-293
    • Contreras, P.C.1
  • 11
    • 0028327289 scopus 로고
    • The NMDA positive modulator D-cycloserine inhibits dopamine-mediated behaviours in the rat
    • Dall'Olio R, Rimondini R, Gandolfi O (1994). The NMDA positive modulator D-cycloserine inhibits dopamine-mediated behaviours in the rat. Neuropharmacology 33:55-59.
    • (1994) Neuropharmacology , vol.33 , pp. 55-59
    • Dall'Olio, R.1    Rimondini, R.2    Gandolfi, O.3
  • 12
    • 0033635444 scopus 로고    scopus 로고
    • D-Cycloserine, a positive modulator of NMDA receptors, inhibits serotonergic functions
    • Dall'Olio R, Gandolfi O, Gaggi R (2000). D-Cycloserine, a positive modulator of NMDA receptors, inhibits serotonergic functions. Behav Pharmacol 11:631-637.
    • (2000) Behav Pharmacol , vol.11 , pp. 631-637
    • Dall'Olio, R.1    Gandolfi, O.2    Gaggi, R.3
  • 13
    • 0033005998 scopus 로고    scopus 로고
    • Prepulse inhibition of the startle reflex in rats: Effects of compounds acting at various sites on the NMDA receptor complex
    • Depoortere R, Perrault G, Sanger DJ (1999). Prepulse inhibition of the startle reflex in rats: effects of compounds acting at various sites on the NMDA receptor complex. Behav Pharmacol 10:51-62.
    • (1999) Behav Pharmacol , vol.10 , pp. 51-62
    • Depoortere, R.1    Perrault, G.2    Sanger, D.J.3
  • 15
    • 0035056929 scopus 로고    scopus 로고
    • The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia
    • Devon RS, Anderson S, Teague PW, Muir WJ, Murray V, Pelosi AJ, et al. (2001). The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia. Mol Psychiatry 6:311-314.
    • (2001) Mol Psychiatry , vol.6 , pp. 311-314
    • Devon, R.S.1    Anderson, S.2    Teague, P.W.3    Muir, W.J.4    Murray, V.5    Pelosi, A.J.6
  • 17
    • 0034843738 scopus 로고    scopus 로고
    • The emerging role of glutamate in the pathophysiology and treatment of schizophrenia
    • Goff DC, Coyle JT (2001). The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am J Psychiatry 158:1367-1377.
    • (2001) Am J Psychiatry , vol.158 , pp. 1367-1377
    • Goff, D.C.1    Coyle, J.T.2
  • 18
    • 0029116094 scopus 로고
    • Dose-finding trial of D-cycloserine in added to neuroleptics for negative symptoms in schizophrenia
    • Goff DC, Tsai G, Manoach DS, Coyle JT (1995). Dose-finding trial of D-cycloserine in added to neuroleptics for negative symptoms in schizophrenia. Am J Psychiatry 152:1213-1215.
    • (1995) Am J Psychiatry , vol.152 , pp. 1213-1215
    • Goff, D.C.1    Tsai, G.2    Manoach, D.S.3    Coyle, J.T.4
  • 20
    • 0033557737 scopus 로고    scopus 로고
    • A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia
    • Goff DC, Henderson D, Evins A, Amico E (1999). A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia. Biol Psychiatry 45:512-514.
    • (1999) Biol Psychiatry , vol.45 , pp. 512-514
    • Goff, D.C.1    Henderson, D.2    Evins, A.3    Amico, E.4
  • 21
    • 0025807544 scopus 로고
    • D-Alanine inhibits methamphetamine-induced hyperactivity in rats
    • Hashimoto A, Nishikava T, Oka T, Takahashi K (1991). D-Alanine inhibits methamphetamine-induced hyperactivity in rats. Eur J Pharmacol 202:105-107.
    • (1991) Eur J Pharmacol , vol.202 , pp. 105-107
    • Hashimoto, A.1    Nishikava, T.2    Oka, T.3    Takahashi, K.4
  • 22
    • 0031897446 scopus 로고    scopus 로고
    • The role of N-methyl-D-aspartate (NMDA) receptor-mediated neurotransmission in the pathophysiology and therapeutics of psychiatric syndromes
    • Heresco-Levy U, Javitt DC (1998). The role of N-methyl-D-aspartate (NMDA) receptor-mediated neurotransmission in the pathophysiology and therapeutics of psychiatric syndromes. Eur Neuropsychopharmacology 8:141-152.
    • (1998) Eur Neuropsychopharmacology , vol.8 , pp. 141-152
    • Heresco-Levy, U.1    Javitt, D.C.2
  • 23
    • 0029658545 scopus 로고    scopus 로고
    • Double-bind placebo-controlled crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia
    • Heresco-Levy U, Javitt D, Ermilov M, Mordel C, Horowits A, Kelly D (1996). Double-bind placebo-controlled crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia. Br J Psychiatry 169:610-617.
    • (1996) Br J Psychiatry , vol.169 , pp. 610-617
    • Heresco-Levy, U.1    Javitt, D.2    Ermilov, M.3    Mordel, C.4    Horowits, A.5    Kelly, D.6
  • 25
    • 0036184549 scopus 로고    scopus 로고
    • Placebo-controlled trial of D-cycloserine added to conventional neuroleptics olanzapine, or risperidone in schizophrenia
    • Heresco-Levy U, Ermilov M, Shimoni J, Shapira B, Silipo G, Javitt DC (2002). Placebo-controlled trial of D-cycloserine added to conventional neuroleptics olanzapine, or risperidone in schizophrenia. Am J Psychiatry 159:480-482.
    • (2002) Am J Psychiatry , vol.159 , pp. 480-482
    • Heresco-Levy, U.1    Ermilov, M.2    Shimoni, J.3    Shapira, B.4    Silipo, G.5    Javitt, D.C.6
  • 26
    • 15444377601 scopus 로고    scopus 로고
    • D-Serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia
    • Heresco-Levy U, Javitt DC, Ebstein R, Vass A, Lichtenberg P, Bar G, et al. (2005). D-Serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia. Biol Psychiatry 57:577-585.
    • (2005) Biol Psychiatry , vol.57 , pp. 577-585
    • Heresco-Levy, U.1    Javitt, D.C.2    Ebstein, R.3    Vass, A.4    Lichtenberg, P.5    Bar, G.6
  • 29
    • 0019293020 scopus 로고
    • Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia
    • Kim JS, Kornhuber HH, Schmid-Burgk W, Holzmuller B (1980). Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia. Neurosci Let 20:379-382.
    • (1980) Neurosci Let , vol.20 , pp. 379-382
    • Kim, J.S.1    Kornhuber, H.H.2    Schmid-Burgk, W.3    Holzmuller, B.4
  • 31
    • 20144381462 scopus 로고    scopus 로고
    • A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models
    • Kinney GG, O'Brien JA, Lemaire W, Burno M, Bickel DJ, Clements MK, et al. (2005). A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models. J Pharmacol Exp Ther 313:199-206.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 199-206
    • Kinney, G.G.1    O'Brien, J.A.2    Lemaire, W.3    Burno, M.4    Bickel, D.J.5    Clements, M.K.6
  • 32
    • 0347091932 scopus 로고    scopus 로고
    • Glutamate, dopamine and schizophrenia from pathophysiology to treatment
    • Laruelle M, Kegeles LS, Abi-Dargham A (2003). Glutamate, dopamine and schizophrenia from pathophysiology to treatment. Ann NY Acad Sci 1003:138-158.
    • (2003) Ann NY Acad Sci , vol.1003 , pp. 138-158
    • Laruelle, M.1    Kegeles, L.S.2    Abi-Dargham, A.3
  • 33
    • 0035882474 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function
    • Mannaioni G, Marino MJ, Valenti O, Traynelis SF, Conn PJ (2001). Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function. J Neurosci 21:5925-5934.
    • (2001) J Neurosci , vol.21 , pp. 5925-5934
    • Mannaioni, G.1    Marino, M.J.2    Valenti, O.3    Traynelis, S.F.4    Conn, P.J.5
  • 34
    • 0032868798 scopus 로고    scopus 로고
    • The role of serotonin in antipsychotic drug action
    • Meltzer HY (1999). The role of serotonin in antipsychotic drug action. Neuropsychopharmacology 21:106-115.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 106-115
    • Meltzer, H.Y.1
  • 35
    • 3142739322 scopus 로고    scopus 로고
    • Targeting metabotropic glutamate receptors for treatment of the cognitive symptoms of schizophrenia
    • Moghaddam B (2004). Targeting metabotropic glutamate receptors for treatment of the cognitive symptoms of schizophrenia. Psychopharmacology 174:39-44.
    • (2004) Psychopharmacology , vol.174 , pp. 39-44
    • Moghaddam, B.1
  • 36
    • 0026757929 scopus 로고
    • The behavioral pharmacology of olanzapine, a novel 'atypical' antipsychotic agent
    • Moore NA, Tye NC, Axton MS, Risius FC (1992). The behavioral pharmacology of olanzapine, a novel 'atypical' antipsychotic agent. J Pharmacol Exp Ther 262:545-551.
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 545-551
    • Moore, N.A.1    Tye, N.C.2    Axton, M.S.3    Risius, F.C.4
  • 37
    • 15144341889 scopus 로고    scopus 로고
    • Subunit specific effects of D-cycloserine on NMDA receptor expressed in Xenopus oocytes
    • O'Connor AJ, Vlachogiannis G, Moskal J, Kelso SR (1996). Subunit specific effects of D-cycloserine on NMDA receptor expressed in Xenopus oocytes. Soc Neurosci Abst 22:1530.
    • (1996) Soc Neurosci Abst , vol.22 , pp. 1530
    • O'Connor, A.J.1    Vlachogiannis, G.2    Moskal, J.3    Kelso, S.R.4
  • 38
    • 0032078391 scopus 로고    scopus 로고
    • Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia
    • Ohnuma T, Augood SJ, Arai H, McKenna PJ, Emson PC (1998). Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Mol Brain Res 56:207-217.
    • (1998) Mol Brain Res , vol.56 , pp. 207-217
    • Ohnuma, T.1    Augood, S.J.2    Arai, H.3    McKenna, P.J.4    Emson, P.C.5
  • 39
    • 0028850552 scopus 로고
    • Glutamate receptor dysfunction and schizophrenia
    • Olney JW, Farber NB (1995). Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry 52:998-1007.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 998-1007
    • Olney, J.W.1    Farber, N.B.2
  • 41
    • 0034648751 scopus 로고    scopus 로고
    • Contributions of mGlu1 and mGlu5 receptors to interactions with N-methyl-D-aspartate receptor-mediated responses and nociceptive sensory responses of rat thalamic neurons
    • Salt TE, Binns KE (2000). Contributions of mGlu1 and mGlu5 receptors to interactions with N-methyl-D-aspartate receptor-mediated responses and nociceptive sensory responses of rat thalamic neurons. Neuroscience 100:375-380.
    • (2000) Neuroscience , vol.100 , pp. 375-380
    • Salt, T.E.1    Binns, K.E.2
  • 42
    • 0033936624 scopus 로고    scopus 로고
    • 2C antagonistic properties of newer antipsychotics
    • 2C antagonistic properties of newer antipsychotics. Behav Pharmacol 11:291-298.
    • (2000) Behav Pharmacol , vol.11 , pp. 291-298
    • Sanchez, C.1    Arnt, J.2
  • 43
    • 0029930927 scopus 로고    scopus 로고
    • Risperidone compared with new and reference antipsychotic drugs: In vitro and in vivo receptor binding
    • Schotte A, Janssen PF, Gommeren W, Luyten WH, Van Gompel P, Lesage AS, et al. (1996). Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology 124:57-73.
    • (1996) Psychopharmacology , vol.124 , pp. 57-73
    • Schotte, A.1    Janssen, P.F.2    Gommeren, W.3    Luyten, W.H.4    Van Gompel, P.5    Lesage, A.S.6
  • 44
    • 0034898096 scopus 로고    scopus 로고
    • Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine
    • Sheinin A, Shavit S, Benveniste M (2001). Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine. Neuropharmacology 41:151-158.
    • (2001) Neuropharmacology , vol.41 , pp. 151-158
    • Sheinin, A.1    Shavit, S.2    Benveniste, M.3
  • 46
    • 0032403626 scopus 로고    scopus 로고
    • D-Serine added to antipsychotics for the treatment of schizophrenia
    • Tsai G, Yang P, Chung L-C, Lange N, Coyle J (1998). D-Serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry 44:1081-1089.
    • (1998) Biol Psychiatry , vol.44 , pp. 1081-1089
    • Tsai, G.1    Yang, P.2    Chung, L.-C.3    Lange, N.4    Coyle, J.5
  • 49
    • 0032974130 scopus 로고    scopus 로고
    • D-Cycloserine increases positive symptoms in chronic schizophrenic patients when administered in addition to antipsychotics: A double-blind, parallel, placebo-controlled study
    • Van Berckel BN, Evenblij CN, Van Loon BJAM, Maas MF, Van der Geld MAM, Wynne HJ, et al. (1999). D-Cycloserine increases positive symptoms in chronic schizophrenic patients when administered in addition to antipsychotics: a double-blind, parallel, placebo-controlled study. Neuropsychopharmacology 21:203-210.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 203-210
    • Van Berckel, B.N.1    Evenblij, C.N.2    Van Loon, B.J.A.M.3    Maas, M.F.4    Van Der Geld, M.A.M.5    Wynne, H.J.6
  • 50
    • 0024286543 scopus 로고
    • Glycine therapy of schizophrenia
    • Waziri R (1988). Glycine therapy of schizophrenia. Biol Psychiatry 23:209-214.
    • (1988) Biol Psychiatry , vol.23 , pp. 209-214
    • Waziri, R.1
  • 51
    • 0033121142 scopus 로고    scopus 로고
    • Selectivity of action of typical and atypical antipsychotic drugs as antagonists of the behavioral effects of 1-2, 5-dimethoxy-4-iodophenyl-2- aminopropane (DOI)
    • Wettstein JG, Host M, Hitchcock JM (1999). Selectivity of action of typical and atypical antipsychotic drugs as antagonists of the behavioral effects of 1-2, 5-dimethoxy-4-iodophenyl-2-aminopropane (DOI). Prog Neuro-psychopharmacol Biol Psychiatry 23:533-544.
    • (1999) Prog Neuro-psychopharmacol Biol Psychiatry , vol.23 , pp. 533-544
    • Wettstein, J.G.1    Host, M.2    Hitchcock, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.