HCaRG increases renal cell migration by a TGF-α autocrine loop mechanism

American Journal of Physiology - Renal Physiology

Volumn 289, Issue 6 58-6, 2005, Pages

  El Hader, Carlos ^a,c   Tremblay, Sandra ^a   Solban, Nicolas ^a   Gingras, Denis ^b   Béliveau, Richard ^b   Orlov, Sergei N ^a   Hamet, Pavel ^a,c   Tremblay, Johanne ^a,c  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Cell motility; Hypertension related, calcium regulated gene; Kidney 293 cells; Kidney repair; Lamellipodia; Madin Darby canine kidney cells; Microarrays

Indexed keywords

AUTOTAXIN; CALCIUM ION; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBRONECTIN; GALECTIN; GENE PRODUCT; MITOMYCIN; PROTEIN HCARG; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG; VINCULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOCRINE EFFECT; CALCIUM TRANSPORT; CELL ADHESION; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HCARG GENE; HUMAN; HUMAN CELL; HYPERTENSION; KIDNEY CELL; KIDNEY INJURY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATOR GENE;

EID: 27944452734     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00103.2005     Document Type: Article

References (27)

1. Abal M, Piel M, Bouckson-Castaing V, Mogensen M, Sibarita JB, and Bornens M. Microtubule release from the centrosome in migrating cells. J Cell Biol 159: 731-737, 2002.
2. Bush KT, Keller SH, and Nigam SK. Genesis and reversal of the ischemie phenotype in epithelial cells. J Clin Invest 106: 621-626, 2000.
3. Devlin AM, Solban N, Tremblay S, Gutkowska J, Schurch W, Orlov SN, Lewanczuk R, Hamet P, and Tremblay J. HCaRG is a novel regulator of renal epithelial cell growth and differentiation causing G2M arrest. Am J Physiol Renal Physiol 284: F753-F762, 2003.
4. Dufourcq P, Couffinhal T, Ezan J, Barandon L, Moreau C, Daret D, and Duplaa C. FrzA, a secreted frizzled related protein, induced angiogenic response. Circulation 106: 3097-3103, 2002.
5. Elferink JG and De Koster BM. Atrial natriuretic factor stimulates migration by human neutrophils. Eur J Pharmacol 288: 335-340, 1995.
6. Hama K, Aoki J, Fukaya M, Kishi Y, Sakai T, Suzuki R, Ohta H, Yamori T, Watanabe M, Chun J, and Arai H. Lysophosphatidic acid and autotaxin stimulate cell motility and non-neoplastic cells through LPA1. J Biol Chem 279: 17634-17639, 2004.
7. Holly SP, Larson MK, and Parise LV. Multiple roles of integrins in cell motility. Exp Cell Res 261: 69-74, 2000.
8. Horie H, Kadoya T, Hikawa N, Sango K, Inoue H, Takeshita K, Asawa R, Hiroi T, Sato M, Yoshioka T, and Ishikawa Y. Oxidized galectin-1 stimulates macrophages to promote axonal regeneration in peripheral nerves after axotomy. J Neurosci 24: 1873-1880, 2004.
9. Ikeda M, Kohno M, Yasunari K, Yokokawa K, Horio T, Ueda M, Morisaki N, and Yoshikawa J. Natriuretic peptide family as a novel antimigration factor of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 17: 731-736, 1997.
10. Jung ID, Lee J, Yun SY, Park CG, Choi WS, Lee HW, Choi OH, Han JW, and Lee HY. Cdc42 and Rac1 are necessary for autotaxin-induced tumor cell motility in A2058 melanoma cells. FEBS Lett 532: 351-356, 2002.
11. Kruger JS and Reddy KB. Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells. Mol Cancer Res 1: 801-809, 2003.
12. Lee LF, Louie MC, Desai SJ, Yang J, Chen HW, Evans CP, and Kung HJ. Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK. Oncogene 23: 2197-2205, 2004.
13. Lee S and Helfman DM. Cytoplasmic p21Cip1 is involved in Ras-induced inhibition of the ROCK/LIMK/cofilin pathway. J Biol Chem 279: 1885-1891, 2004.
14. Leeb SN, Vogl D, Grossmann J, Falk W, Scholmerich J, Rogler G, and Gelbmann CM. Autocrine fibronectin-induced migration of human colonic fibroblasts. Am J Gastroenterol 99: 335-340, 2004.
15. Maeda N, Kawada N, Seki S, Arakawa T, Ikeda K, Iwao H, Okuyama H, Hirabayashi J, Kasai K, and Yoshizato K. Stimulation of proliferation of rat hepatic stellate cells by galectin-1 and galectin-3 through different intracellular signaling pathways. J Biol Chem 278: 18938-18944, 2003.
16. 3 Integrin expression up-regulates cdc2, which modulates cell migration. J Cell Biol 161: 817-826, 2003.
17. Maxwell CA, Keats JJ, Crainie M, Sun X, Yen T, Shibuya E, Hendzel M, Chan G, and Pilarski LM. RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability. Mol Biol Cell 14: 2262-2276, 2003.
18. Nakajima T, Miyaji T, Kato A, Ikegaya N, Yamamoto T, and Hishida A. Uninephrectomy reduces apoptotic cell death and enhances renal tubular cell regeneration in ischemic ARF in rats. Am J Physiol Renal Fluid Electrolyte Physiol 271: F846-F853, 1996.
19. Nakano T, Tani M, Ishibashi Y, Kimura K, Park YB, Imaizumi N, Tsuda H, Aoyagi K, Sasaki H, Ohwada S, and Yokota J. Biological properties and gene expression associated with metastatic potential of human osteosarcoma. Clin Exp Metastasis 20: 665-674, 2003.
20. Nony PA and Schnellmann RG. Mechanisms of renal cell repair and regeneration after acute renal failure. J Pharmacol Exp Ther 304: 905-912, 2003.
21. Pedram A, Razandi M, and Levin ER. Natriuretic peptides suppress vascular endothelial cell growth factor signaling to angiogenesis. Endocrinology 142: 1578-1586, 2001.
22. Solari V, Shima H, and Puri P. Increased expression of EGFR and TGF-α in segmental renal dysplasia in duplex kidney. Pediatr Surg Int 20: 243-247, 2004.
23. Solban N, Jia HP, Richard S, Tremblay S, Devlin AM, Peng J, Gossard F, Guo DF, Morel G, Hamet P, Lewanczuk R, and Tremblay J. HCaRG, a novel calcium-regulated gene coding for a nuclear protein, is potentially involved in the regulation of cell proliferation. J Biol Chem 275: 32234-32243, 2000.
24. Stracke ML, Clair T, and Liotta LA. Autotaxin, tumor motility-stimulating exophosphodiesterase. Adv Enzyme Regul 37: 135-144, 1997.
25. 1-mediated inhibition of HK-2 cell migration. J Am Soc Nephrol 14: 631-640, 2003.
26. Visse R and Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92: 827-839, 2003.
27. Wells A. EGF receptor. Int J Biochem Cell Biol 31: 637-643, 1999.