FrzA, a secreted frizzled related protein, induced angiogenic response

Circulation

Volumn 106, Issue 24, 2002, Pages 3097-3103

  Dufourcq, Pascale ^a,b   Couffinhal, Thierry ^c   Ezan, Jérome ^a   Barandon, Laurent ^a   Moreau, Catherine ^a   Daret, Daniéle ^a   Duplàa, Cécile ^a  

^a INSERM   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c HAUT LÉVÊQUE HOSPITAL   (France)

Author keywords

Angiogenesis; Endothelium; Muscle, smooth

Indexed keywords

ANGIOPOIETIN 1; FIBROBLAST GROWTH FACTOR 2; FRIZZLED RELATED PROTEIN; PROTEIN KINASE B; REGULATOR PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; WNT PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTERY ENDOTHELIUM; ARTICLE; CAPILLARY ENDOTHELIUM; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CHICKEN; CHORIOALLANTOIS; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE TRANSFER; GLIOMA CELL; HUMAN; HUMAN CELL; MESENCHYME; MOUSE; NONHUMAN; OVARY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; VASCULAR SMOOTH MUSCLE;

ALLANTOIS; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CELL MOVEMENT; CHICK EMBRYO; CHORION; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; FEMALE; GLIOMA; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MORPHOGENESIS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; OVARY; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0037058830     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000039342.85015.5C     Document Type: Article

References (28)

1. Cadigan KM, Nusse R. Wnt signaling: A common theme in animal development. Genes Dev. 1997;11:3286-3305.
2. Bhanot P. Brink M, Samos CH, et al. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature. 1996; 382:225-230.
3. He X, Saint-Jeannet J-P. Wang Y, et al. A member of the frizzled protein family mediating axis induction by Wnt-5A. Science. 1997;275: 1652-1654.
4. Ishikawa T, Tamai Y, Zorn AM. et al. Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development. 2001; 128:25-33.
5. Blankesteijn WM, van Gijn ME, Essers-Janssen YP, et al. β-catenin, an inducer of uncontrolled cell proliferation and migration in malignancies, is localized in the cytoplasm of vascular endothelium during neovascularization after myocardial infarction. Am J Pathol. 2000;157:877-883.
6. Wright M, Aikawa M, Szeto W, et al. Identification of a Wnt-responsive signal transduction pathway in primary endothelial cells. Biochem Biophys Res Commun. 1999;263:384-388.
7. Rattner A, Hsieh JC, Smallwood PM, et al. A family of secreted proteins contains homology to the cysteine-rich ligand binding domain of frizzled receptors. Proc Natl Acad Sci U S A. 1997;94:2859-2863.
8. Finch PW, He X, Kelley MJ, et al. Purification and molecular cloning of a secreted, frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A. 1997;94:6770-6775.
9. Bafico A, Gazit A, Pramila T, et al. Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. J Biol Chem. 1999; 274:16180-16187.
10. Dupláa C, Jaspard B, Moreau C, et al. Identification and cloning of a secreted protein related to the cysteine-rich domain of frizzled: Evidence for a role in endothelial cell growth control. Circ Res. 1999;84: 1433-1445.
11. Xu Q. D'Amore PA, Sokol SY. Functional and biochemical interactions of Wnts with FrzA, a secreted Wnt antagonist. Development. 1998;125: 4767-4776.
12. Jaspard B, Couffinhal T, Dufourcq P, et al. Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart morphogenesis. Mech Dev. 2000; 90:263-267.
13. Dennis S, Aikawa M, Szeto W. et al. A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates Wnt-1 signaling. J Cell Sci. 1999;112:3815-3820.
14. Dufourcq P, Couffinhal T, Alzieu P, et al. Vitronectin is up regulated after vascular injury and vitronectin blockade prevents neointima formation. Cardiovasc Res. 2002;53:952-962.
15. Fromes Y, Salmon A, Wang X, et al. Gene delivery to the myocardium by intrapericardial injection. Gene Ther. 1999;6:683-688.
16. Auerbach R, Kubai L, Knighton D, et al. A simple procedure for the long-term cultivation of chicken embryos. Dev Biol. 1974;41:391-394.
17. Goede V, Schmidt T, Kimmina S, et al. Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis. Lab Invest. 1998;78: 1385-1394.
18. Hirschi KK, Rohovsky SA, D'Amore PA. PDGF, TGF-β and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10TI/2 cells and their differentiation to a smooth muscle fate. J Cell Biol. 1998;141:805-814.
19. Roth W, Wild-Bode C, Platten M, et al. Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells. Oncogene. 2000;19:4210-4220.
20. Pettersson A, Nagy JA, Brown LF, et al. Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor. Lab Invest. 2000;80: 99-115.
21. Benjamin LE, Hemo I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development. 1998; 125:1591-1598.
22. Melkonyan HS, Chang WC, Shapiro JP, et al. SARPs: A family of secreted apoptosis-related proteins. Proc Natl Acad Sci U S A. 1997;94: 13636-13641.
23. Zhou Z, Wang J, Han X. et al. Up-regulation of human secreted frizzled homolog in apoptosis and its down-regulation in breast tumors. Int J Cancer. 1998;78:95-99.
24. Ugolini F, Adelaide J, Charafe-Jauffret E, et al. Differential expression assay of chromosome arm 8p genes identifies Frizzled-related (FRPI/FRZB) and fibroblast growth factor receptor 1 (FGFRI) as candidate breast cancer genes. Oncogene. 1999;18:1903-1910.
25. Lisovsky M, Itoh K, Sokol SY. Frizzled receptors activate a novel JNK-dependent pathway that may lead to apoptosis. Curr 2002;12: 53-58.
26. Uren A, Reichsman F, Anest V, et al. Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasi-modulator of Wnt signaling. J Biol Chem. 2000;275:4374-4382.
27. Jiang BH, Zheng JZ, Aoki M, et al. Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells. Proc Natl Acad Sci U S A. 2000;97: 1749-1753.
28. Fukumoto S, Hsieh CM, Maemura K, et al. Akt participation in the Wnt signaling pathway through Dishevelled. J Biol Chem. 2001;276: 17479-17483.