Loss of ovarian function and the risk of ovarian cancer

Cell and Tissue Research

Volumn 322, Issue 1, 2005, Pages 117-124

  Vanderhyden, Barbara C ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b OTTAWA REGIONAL CANCER CENTRE   (Canada)

Author keywords

Hormonal changes; Human; Oocyte deficiency; Ovarian cancer; Premature ovarian failure

Indexed keywords

FOLLITROPIN RECEPTOR; GONADOTROPIN; ORAL CONTRACEPTIVE AGENT; PROGESTERONE;

AGING; CANCER RISK; CARCINOGENESIS; CELL LOSS; CELL MIGRATION; CELL PROLIFERATION; EPITHELIUM; GENETIC POLYMORPHISM; GERM CELL; GONAD; GONAD DEVELOPMENT; HUMAN; NONHUMAN; OOCYTE; OVARY CANCER; OVARY FOLLICLE DEVELOPMENT; OVARY FUNCTION; OVARY INSUFFICIENCY; PATHOGENESIS; PHENOTYPE; POSTMENOPAUSE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; THEORETICAL STUDY;

ANIMALS; FEMALE; GERM CELLS; GONADOTROPINS; HUMANS; OOCYTES; OVARIAN NEOPLASMS; OVARY; PROGESTERONE; RISK FACTORS;

ANIMALIA;

EID: 27944442873     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-005-1100-1     Document Type: Review

References (70)

1. Adami HO, Hsieh CC, Lambe M, Trichopoulos D, Leon D, Persson I, Ekbom A, Janson PO (1994) Parity, age at first childbirth, and risk of ovarian cancer. Lancet 344:1250-1254
2. Agoulnik IU, Tong XW, Fischer DC, Korner K, Atkinson NE, Edwards DP, Headon DR, Weigel NL, Kieback DG (2004) A germline variation in the progesterone receptor gene increases transcriptional activity and may modify ovarian cancer risk. J Clin Endocrinol Metab 89:6340-6347
3. Auersperg N, Wong AS, Choi KC, Kang SK, Leung PC (2001) Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr Rev 22:255-288
4. Biskind MS, Biskind GS (1944) Development of tumors in the rat ovary after transplantation into the spleen. Proc Soc Exp Biol Med 55:176-179
5. Blaakaer J, Baeksted M, Micic S, Albrectsen P, Rygaard J, Bock J (1995) Gonadotropin-releasing hormone agonist suppression of ovarian tumorigenesis in mice of the Wx/Wv genotype. Biol Reprod 53:775-779
6. Bukovsky A, Caudle MR, Svetlikova M, Upadhyaya NB (2004) Origin of germ cells and formation of new primary follicles in adult human ovaries. Reprod Biol Endocrinol 2:20
7. Burmeister L, Healy DL (1998) Ovarian cancer in infertility patients. Ann Med 30:525-528
8. Cancer Surveillance On-Line Public Health Agency of Canada. http://www.dsol-smed.hc-sc.gc.ca/dsol-smed/cancer/index_e.html
9. Capen CC, Beamer WG, Tennent BJ, Stitzel KA (1995) Mechanisms of hormone-mediated carcinogenesis of the ovary in mice. Mutat Res 333:143-151
10. Capo-Chichi CD, Smith ER, Yang DH, Roland IH, Vanderveer L, Cohen C, Hamilton TC, Godwin AK, Xu XX (2002) Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis. Cancer 95:1802-1815
11. Castrillon DH, Miao L, Kollipara R, Horner JW, DePinho RA (2003) Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science 301:215-218
12. Celik C, Gezginc K, Aktan M, Acar A, Yaman ST, Gungor S, Akyurek C (2004) Effects of ovulation induction on ovarian morphology: an animal study. Int J Gynecol Cancer 14:600-606
13. Chakravarti S, Collins WP, Forecast JD, Newton JR, Oram DH, Studd JW (1976) Hormonal profiles after the menopause. BMJ 2:784-787
14. Cho BN, McMullen ML, Pei L, Yates CJ, Mayo KE (2001) Reproductive deficiencies in transgenic mice expressing the rat inhibin alpha-subunit gene. Endocrinology 142:4994-5004
15. Cramer DW, Welch WR (1983) Determinants of ovarian cancer risk: II. Inferences regarding pathogenesis. J Natl Cancer Inst 71:717-721
16. Danilovich N, Roy I, Sairam MR (2001) Ovarian pathology and high incidence of sex cord tumors in follitropin receptor knockout (FORKO) mice. Endocrinology 142:3673-3684
17. Danilovich N, Maysinger D, Sairam MR (2004) Perspectives on reproductive senescence and biological aging: studies in genetically altered follitropin receptor knockout [FORKO] mice. Exp Gerontol 39:1669-1678
18. Davies BR, Finnigan DS, Smith SK, Ponder BA (1999) Administration of gonadotropins stimulates proliferation of normal mouse ovarian surface epithelium. Gynecol Endocrinol 13:75-81
19. Dong J, Albertini DF, Nishimori K, Kumar TR, Lu N, Matzuk MM (1996) Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature 383:531-535
20. Dubeau L (1999) The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes? Gynecol Oncol 72:437-442
21. Duncan MK, Chada KK (1993) Incidence of tubulostromal adenoma of the ovary in aged germ cell-deficient mice. J Comp Pathol 109:13-19
22. Ishimura K, Matsuda H, Tatsumi H, Fujita H, Terada N, Kitamura Y (1986) Ultrastructural changes in the ovaries of Sl/Slt mutant mice, showing developmental deficiency of follicles and tubular adenomas. Arch Histol Jpn 49:379-389
23. Ivarsson K, Sundfeldt K, Brannstrom M, Janson PO (2001) Production of steroids by human ovarian surface epithelial cells in culture: possible role of progesterone as growth inhibitor. Gynecol Oncol 82:116-121
24. Johnson J, Canning J, Kaneko T, Pru JK, Tilly JL (2004) Germline stem cells and follicular renewal in the postnatal mammalian ovary. Nature 428:145-150
25. Kabawat SE, Bast RC Jr, Bhan AK, Welch WR, Knapp RC, Colvin RB (1983) Tissue distribution of a coelomic-epithelium-related antigen recognized by the monoclonal antibody OC125. Int J Gynecol Pathol 2:275-285
26. Karl J, Capel B (1998) Sertoli cells of the mouse testis originate from the coelomic epithelium. Dev Biol 203:323-333
27. Keri RA, Lozada KL, Abdul-Karim FW, Nadeau JH, Nilson JH (2000) Luteinizing hormone induction of ovarian tumors: oligogenic differences between mouse strains dictates tumor disposition. Proc Natl Acad Sci USA 97:383-387
28. Kirchner T, Brabletz T (2000) Patterning and nuclear beta-catenin expression in the colonic adenoma-carcinoma sequence: analogies with embryonic gastrulation. Am J Pathol 157:1113-1121
29. Kumar TR, Palapattu G, Wang P, Woodruff TK, Boime I, Byrne MC, Matzuk MM (1999) Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis. Mol Endocrinol 13:851-865
30. La Vecchia C, Franceschi S (1999) Oral contraceptives and ovarian cancer. Eur J Cancer Prev 8:297-304
31. Liebelt AG, Sass B, Lombard LS (1987) Mouse ovarian tumors - a review including classification and induction of neoplastic lesions and description of several previously unreported types. J Exp Pathol 3:115-145
32. Lubahn DB, Moyer JS, Golding TS, Couse JF, Korach KS, Smithies O (1993) Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc Natl Acad Sci USA 90:11162-11166
33. Matzuk MM, Finegold MJ, Su JG, Hsueh AJ, Bradley A (1992) Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature 360:313-319
34. Matzuk MM, Burns KH, Viveiros MM, Eppig JJ (2002) Intercellular communication in the mammalian ovary: oocytes carry the conversation. Science 296:2178-2180
35. Mazaud S, Oreal E, Guigon CJ, Carre-Eusebe D, Magre S (2002) Lhx9 expression during gonadal morphogenesis as related to the state of cell differentiation. Gene Expr Patterns 2:373-377
36. McMullen ML, Cho BN, Yates CJ, Mayo KE (2001) Gonadal pathologies in transgenic mice expressing the rat inhibin alpha-subunit. Endocrinology 142:5005-5014
37. Mintz B, Russel ES (1957) Gene-induced embryological modification of primordial germ cells in the mouse. J Exp Zool 134:207-237
38. Murphy ED (1972) Hyperplastic and early neoplastic changes in the ovaries of mice after genic deletion of germ cells. J Natl Cancer Inst 48:1283-1295
39. Murphy ED, Beamer WG (1973) Plasma gonadotropin levels during early stages of ovarian tumorigenesis in mice of the Wx/Wv genotype. Cancer Res 33:721-723
40. Naora H, Montz FJ, Chai CY, Roden RB (2001) Aberrant expression of homeobox gene HOXA7 is associated with Mullerian-like differentiation of epithelial ovarian tumors and the generation of a specific autologous antibody response. Proc Natl Acad Sci USA 98:15209-15214
41. Nishizuka Y, Sakakura T, Taguchi O (1979) Mechanism of ovarian tumorigenesis in mice after neonatal thymectomy. Natl Cancer Inst Monogr 51:89-96
42. Osterholzer HO, Johnson JH, Nicosia SV (1985) An autoradiographic study of rabbit ovarian surface epithelium before and after ovulation. Biol Reprod 33:729-738
43. Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM (2004) NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science 305:1157-1159
44. Risma KA, Clay CM, Nett TM, Wagner T, Yun J, Nilson JH (1995) Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors. Proc Natl Acad Sci USA 92:1322-1326
45. Rodriguez GC, Walmer DK, Cline M, Krigman H, Lessey BA, Whitaker RS, Dodge R, Hughes CL (1998) Effect of progestin on the ovarian epithelium of macaques: cancer prevention through apoptosis? J Soc Gynecol Investig 5:271-276
46. Roland IH, Yang WL, Yang DH, Daly MB, Ozols RF, Hamilton TC, Lynch HT, Godwin AK, Xu XX (2003) Loss of surface and cyst epithelial basement membranes and preneoplastic morphologic changes in prophylactic oophorectomies. Cancer 98:2607-2623
47. Salazar H, Godwin AK, Daly MB, Laub PB, Hogan WM, Rosenblum N, Boente MP, Lynch HT, Hamilton TC (1996) Microscopic benign and invasive malignant neoplasms and a cancer-prone phenotype in prophylactic oophorectomies. J Natl Cancer Inst 88:1810-1820
48. Scaglia H, Medina M, Pinto-Ferreira AL, Vazques G, Gual C, Perez-Palacios G (1976) Pituitary LH and FSH secretion and responsiveness in women of old age. Acta Endocrinol (Copenh) 81:673-679
49. Schiffenbauer YS, Abramovitch R, Meir G, Nevo N, Holzinger M, Itin A, Keshet E, Neeman M (1997) Loss of ovarian function promotes angiogenesis in human ovarian carcinoma. Proc Natl Acad Sci USA 94:13203-13208
50. Schmahl J, Eicher EM, Washburn LL, Capel B (2000) Sry induces cell proliferation in the mouse gonad. Development 127:65-73
51. Scully RE (1995) Pathology of ovarian cancer precursors. J Cell Biochem Suppl 23:208-218
52. Sell A, Bertelsen K, Andersen JE, Stroyer I, Panduro J (1990) Randomized study of whole-abdomen irradiation versus pelvic irradiation plus cyclophosphamide in treatment of early ovarian cancer. Gynecol Oncol 37:367-373
53. Steller M, Shaw TJ, Vanderhyden BC, Ethier J-F (2005) Inhibin resistance is associated with aggressive tumorigenicity of ovarian cancer cells. Mol Cancer Res 3:1-12
54. Stewart SL, Querec TD, Gruver BN, O'Hare B, Babb JS, Patriotis C (2004a) Gonadotropin and steroid hormones stimulate proliferation of the rat ovarian surface epithelium. J Cell Physiol 198:119-124
55. Stewart SL, Querec TD, Ochman AR, Gruver BN, Bao R, Babb JS, Wong TS, Koutroukides T, Pinnola AD, Klein-Szanto A, Hamilton TC, Patriotis C (2004b) Characterization of a carcinogenesis rat model of ovarian preneoplasia and neoplasia. Cancer Res 64:8177-8183
56. Stoica G, Koestner A, Capen CC (1985) Testicular (Sertoli's cell)-like tumors of the ovary induced by N-ethyl-N-nitrosourea (ENU) in rats. Vet Pathol 22:483-491
57. Sundfeldt K, Piontkewitz Y, Ivarsson K, Nilsson O, Hellberg P, Brannstrom M, Janson PO, Enerback S, Hedin L (1997) E-cadherin expression in human epithelial ovarian cancer and normal ovary. Int J Cancer 74:275-280
58. Teixeira Filho FL, Baracat EC, Lee TH, Suh CS, Matsui M, Chang RJ, Shimasaki S, Erickson GF (2002) Aberrant expression of growth differentiation factor-9 in oocytes of women with polycystic ovary syndrome. J Clin Endocrinol Metab 87:1337-1344
59. Tennent BJ, Beamer WG (1986) Ovarian tumors not induced by irradiation and gonadotropins in hypogonadal (hpg) mice. Biol Reprod 34:751-760
60. Tonary AM, Macdonald EA, Faught W, Senterman MK, Vanderhyden BC (2000) Lack of expression of c-KIT in ovarian cancers is associated with poor prognosis. Int J Cancer 89:242-250
61. Vainio S, Heikkila M, Kispert A, Chin N, McMahon AP (1999) Female development in mammals is regulated by Wnt-4 signalling. Nature 397:405-409
62. Vanderhyden BC (2002) Molecular basis of ovarian development and function. Front Biosci 7:2006-2022
63. Vanderhyden BC, Caron PJ, Buccione R, Eppig JJ (1990) Developmental pattern of the secretion of cumulus expansion-enabling factor by mouse oocytes and the role of oocytes in promoting granulosa cell differentiation. Dev Biol 140:307-317
64. Vanderhyden BC, Telfer EE, Eppig JJ (1992) Mouse oocytes promote proliferation of granulosa cells from preantral and antral follicles in vitro. Biol Reprod 46:1196-1204
65. Vanderhyden BC, Shaw TJ, Ethier J-F (2003a) Animal models of ovarian cancer. Reprod Biol Endocrinol 1:67
66. Vanderhyden BC, Shaw TJ, Garson K, Tonary AM (2003b) Ovarian carcinogenesis. In: Leung PCK, Adashi EY (eds) The ovary, 2nd edn. Elsevier Academic, San Diego, pp 591-612
67. Wang DP, Konishi I, Koshiyama M, Nanbu Y, Iwai T, Nonogaki H, Mori T, Fujii S (1992) Immunohistochemical localization of c-erbB-2 protein and epidermal growth factor receptor in normal surface epithelium, surface inclusion cysts, and common epithelial tumours of the ovary. Virchows Arch, A Pathol Anat Histopathol 421:393-400
68. Whittemore AS, Harris R, Itnyre J (1992) Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies. IV. The pathogenesis of epithelial ovarian cancer. Collaborative Ovarian Cancer Group. Am J Epidemiol 136:1212-1220
69. Yao HH, DiNapoli L, Capel B (2003) Meiotic germ cells antagonize mesonephric cell migration and testis cord formation in mouse gonads. Development 130:5895-5902
70. Yao HH, Matzuk MM, Jorgez CJ, Menke DB, Page DC, Swain A, Capel B (2004) Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn 230:210-215