Relationship between serum valproate and lithium levels and efficacy and tolerability in bipolar maintenance therapy

International Journal of Psychiatry in Clinical Practice

Volumn 9, Issue 4, 2005, Pages 271-277

  Keck Jr , Paul E ^a   Bowden, Charles L ^c   Meinhold, Jane M ^b   Gyulai, Laszlo ^d   Prihoda, Thomas J ^c   Baker, Jeffrey D ^b   Wozniak, Patricia J ^b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b ABBOTT LABORATORIES   (United States)

^c Mays Cancer Center at UT Health San Antonio   (United States)

^d HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Bipolar maintenance; Lithium; Valproate

Indexed keywords

LITHIUM; PLACEBO; VALPROATE SEMISODIUM;

ADULT; ARTICLE; BIPOLAR I DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MANIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURVIVAL; SURVIVAL TIME; TREATMENT WITHDRAWAL;

EID: 27844497044     PISSN: 13651501     EISSN: None     Source Type: Journal    
DOI: 10.1080/13651500500305622     Document Type: Article

References (23)

1. Judd LL, Akiskal HS, Schettler PJ, et al. A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder. Arch Gen Psychiatry 2003;60:261-9.
2. Judd LL, Akiskal HS, Schettler PJ, et al. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 2002;59:530-7.
3. Practice guideline for the treatment of patients with bipolar disorder (revision). Am J Psychiatry 2002;159:1-50.
4. Suppes T, Baldessarini RJ, Faedda GL, et al. Risk of recurrence following discontinuation of lithium treatment in bipolar disorder. Arch Gen Psychiatry 1991;48:1082-8.
5. Bowden CL, Calabrese JR, Sachs G, et al. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch Gen Psychiatry 2003;60:392-400.
6. Bowden CL, Calabrese JR, McElroy SL, et al. A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Divalproex Maintenance Study Group. Arch Gen Psychiatry 2000;57:481-9.
7. Bowden CL, Swann AC, Calabrese JR, et al. Maintenance clinical trials in bipolar disorder: Design implications of the divalproex-lithium-placebo study. Psychopharmacol Bull 1997;33:693-9.
8. Gelenberg AJ, Kane JM, Keller MB, et al. Comparison of standard and low serum levels of lithium for maintenance treatment of bipolar disorder. New Engl J Med 1989;321:1489-93.
9. Hopkins HS, Gelenberg AJ. Serum lithium levels and the outcome of maintenance therapy of bipolar disorder. Bipolar Disorder 2000;2:174-9.
10. Sproule B. Lithium in bipolar disorder: can drug concentrations predict therapeutic effect? Clin Pharmacokinet 2002;41:639-60.
11. Bowden CL, Brugger AM, Swann AC, et al. Efficacy of divalproex vs lithium and placebo in the treatment of mania. The Depakote Mania Study Group. J Am Med Assoc 1994;271:918-24.
12. Pope HG Jr, McElroy SL, Keck PE Jr, et al. Valproate in the treatment of acute mania. A placebo-controlled study. Arch Gen Psychiatry 1991;48:62-8.
13. Calabrese JR, Delucchi GA. Spectrum of efficacy of valproate in 55 patients with rapid-cycling bipolar disorder. Am J Psychiatry 1990;147:431-4.
14. McElroy SL, Keck PE Jr, Pope HG Jr. Sodium valproate: its use in primary psychiatric disorders. J Clin Psychopharmacol 1987;7:16-24.
15. Lambert P, Venaud G. Comparative study of valpromide versus lithium in the treatment of affective disorders. Nervure 1992;5:57-65.
16. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Revised 3rd ed. Washington, DC: American Psychiatric Association; 1987.
17. Spitzer R, Williams J, Gibbons M, et al. Structured clinical interview for the DSM-III-R. Washington, DC: American Psychiatric Press Inc; 1990.
18. Lawless J. Statistical models and methods for lifetime data. New York: John Wiley & Sons; 1982.
19. Gyulai L, Bowden CL, McElroy SL, et al. Maintenance efficacy of divalproex in the prevention of bipolar depression. Neuropsychopharmacology 2003;28:1374-82.
20. Baldessarini RJ, Tohen M, Tondo L. Maintenance treatment in bipolar disorder. Arch Gen Psychiatry 2000;57:490-2.
21. Prien RF, Caffey EM Jr, Klett CJ. Factors associated with treatment success in lithium carbonate prophylaxis. Report of the Veterans Administration and National Institute of Mental Health collaborative study group. Arch Gen Psychiatry 1974;31:189-92.
22. Tondo L, Baldessarini RJ, Hennen J, et al. Lithium maintenance treatment of depression and mania in bipolar I and bipolar II disorders. Am J Psychiatry 1998;155:638-45.
23. Berghofer A, Kossmann B, Muller-Oerlinghausen B. Course of illness and pattern of recurrences in patients with affective disorders during long-term lithium prophylaxis: A retrospective analysis over 15 years. Acta Psychiatr Scand 1996;93:349-54.