Characterization of an iodothyronine 5′-deiodinase in gilthead seabream (Sparus auratus) that is inhibited by dithiothreitol

Endocrinology

Volumn 146, Issue 12, 2005, Pages 5621-5630

  Klaren, Peter H M ^a   Haasdijk, Remco ^a,b   Metz, Juriaan R ^a   Nitsch, Lisette M C ^a   Darras, Veerle M ^b   Van Der Geyten, Serge ^b   Flik, Gert ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DEIODINASE TYPE 1; DITHIOTHREITOL; ENZYME; LIOTHYRONINE; MESSENGER RNA; PROPYLTHIOURACIL; SELENOCYSTEINE; THYROXINE DEIODINASE; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CODON; CONTROLLED STUDY; DEIODINATION; GENE INSERTION SEQUENCE; IC 50; INCUBATION TIME; KIDNEY; MICHAELIS MENTEN KINETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SPARUS AURATUS; TELEOST; VERTEBRATE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CODON; CONSENSUS SEQUENCE; DITHIOTHREITOL; DNA, COMPLEMENTARY; IODIDE PEROXIDASE; IODINE; KIDNEY; KINETICS; MICROSOMES; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; SEA BREAM; SELENOCYSTEINE; TRIIODOTHYRONINE, REVERSE;

EID: 27844489520     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-0050     Document Type: Article

References (52)

1. Berry MJ, Kieffer JD, Harney JW, Larsen PR 1991 Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase. J Biol Chem 266:14155-14158
2. Visser TJ 1996 Pathways of thyroid hormone metabolism. Acta Med Austriaca 23:10-16
3. Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR 2002 Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev 23:38-89
4. Cleland WW 1964 Dithiothreitol, a new protective reagent for SH groups. Biochemistry 3:480-482
5. +-ATPase in the euryhaline teleost Fundulus heteroclitus. J Exp Zool 287:263-274
6. Mancera JM, McCormick SD 1999 Influence of cortisol, growth hormone, insulin-like growth factor I and 3,3′,5-triiodo-L-thyronine on hypoosmregulatory ability in the euryhaline teleost Fundulus heteroclitus. Fish Physiol Biochem 21:25-33
7. Peter MCS, Lock RAC, Wendelaar Bonga SE 2000 Evidence for an osmoregulatory role of thyroid hormones in the freshwater Mozambique tilapia Oreochromis mossambicus. Gen Comp Endocrinol 120:157-167
8. Klaren PHM, Guzmán JM, Mancera JM, Geven EJW, Flik G 2005 The involvement of thyroid hormone metabolism in gilthead seabream (Sparus auratus) osmoregulation. Ann NY Acad Sci 1040:360-362
9. Byamungu N, Mol K, Kühn ER 1992 Evidence for the kidney as an important source of 5′-monodeiodination activity and stimulation by somatostatin in Oreochromis niloticus L. Gen Comp Endocrinol 88:199-208
10. Mol KA, Van der Geyten S, Darras VM, Visser TJ, Kühn ER 1997 Characterization of iodothyronine outer ring and inner ring deiodinase activities in the blue tilapia, Oreochromis aureus. Endocrinology 138:1787-1793
11. Mol KA, Van der Geyten S, Burel C, Kühn ER, Boujard T, Darras VM 1998 Comparative study of iodothyronine outer ring and inner ring deiodinase activities in five teleostean fishes. Fish Physiol Biochem 18:253-266
12. van der Heide SM, Visser TJ, Everts ME, Klaren PHM 2002 Metabolism of thyroid hormones in cultured cardiac fibroblasts of neonatal rats. J Endocrinol 172:111-119
13. Sanger F, Nicklen S, Coulson AR 1977 DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467
14. Leatherbarrow RJ 1987 Enzfitter. A non-linear regression data analysis program for the IBM PC. Amsterdam: Elsevier Science Publishers BV
15. Marquardt DW 1963 An algorithm for least squares estimation of parameters. J Soc Ind Appl Math 11:431-441
16. Sanders JP, Van der Geyten S, Kaptein E, Darras VM, Kühn ER, Leonard JL, Visser TJ 1997 Characterization of a propylthiouracil-insensitive type I iodothyronine deiodinase. Endocrinology 138:5153-5160
17. Köhrle J 1999 Local activation and inactivation of thyroid hormones: the deiodinase family. Mol Cell Endocrinol 151:103-119
18. Grundner-Culemann E, Martin 3rd GW, Harney JW, Berry MJ 1999 Two distinct SECIS structures capable of directing selenocysteine incorporation in eukaryotes. RNA 5:625-635
19. Fagegaltier D, Lescure A, Walczak R, Carbon P, Krol A 2000 Structural analysis of new local features in SECIS RNA hairpins. Nucleic Acids Res 28:2679-2689
20. Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guigó R, Gladyshev VN 2003 Characterization of mammalian selenoproteomes. Science 300:1439-1443
21. Sanders JP, Van der Geyten S, Kaptein E, Darras VM, Kühn ER, Leonard JL, Visser TJ 1999 Cloning and characterization of type III iodothyronine deiodinase from the fish Oreochromis niloticus. Endocrinology 140:3666-3673
22. White SH, Wimley WC 1999 Membrane protein folding and stability: physical principles. Annu Rev Biophys Biomol Struct 28:319-365
23. Callebaut I, Curcio-Morelli C, Mornon J-P, Gereben B, Buettner C, Huang S, Castro B, Fonseca TL, Harney JW, Larsen PR, Bianco AC. 2003 The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure. J Biol Chem 278:36887-36896
24. Croteau W, Bodwell JE, Richardson JM, St. Germain DL 1998 Conserved cysteines in the type 1 deiodinase selenoprotein are not essential for catalytic activity. J Biol Chem 273:25230-25236
25. Toyoda N, Harney JW, Berry MJ, Larsen PR 1994 Identification of critical amino acids for 3,5,3′-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes. J Biol Chem 269:20329-20334
26. Toyoda N, Kaptein E, Berry MJ, Harney JW, Larsen PR, Visser TJ 1997 Structure-activity relationships for thyroid hormone deiodination by mammalian type I iodothyronine deiodinases. Endocrinology 138:213-219
27. Kuiper GGJM, Wassen F, Klootwijk W, van Toor H, Kaptein E, Visser TJ 2003 Molecular basis for the substrate selectivity of cat type I iodothyronine deiodinase. Endocrinology 144:5411-5421
28. Leonard JL, Simpson G, Leonard DM 2005 Characterization of the protein dimerization domain responsible for assembly of functional selenodeiodinases. J Biol Chem 280:11093-11100
29. Toyoda N, Berry MJ, Harney JW, Larsen PR 1995 Topological analysis of the integral membrane protein, type 1 iodothyronine deiodinase (D1). J Biol Chem 270:12310-12318
30. Yamada T, Chopra IJ, Kaplowitz N 1981 Inhibition of rat hepatic thyroxine 5′-monodeiodinase by propylthiouracil: relation to site of interaction of thyroxine and glutathione. J Endocrinol Invest 4:379-387
31. Goswami A, Rosenberg IN 1984 Iodothyronine 5′-deiodinase in rat kidney microsomes. Kinetic behavior at low substrate concentrations. J Clin Invest 74:2097-2106
32. Sato K, Robbins J 1984 Does glutathione regulate thyroxine deiodinase activity in cells? Horm Metab Res Suppl 14:30-35
33. Goswami A, Rosenberg IN 1988 Effects of glutathione on iodothyronine 5′-deiodinase activity. Endocrinology 123:192-202
34. Goswami A, Rosenberg IN 1990 Purification and partial characterization of iodothyronine 5′-deiodinase from rat liver microsomes. Biochem Biophys Res Commun 173:6-12
35. m activity. Evidence that rat liver and kidney contain a single enzyme which converts thyroxine to 3,5,3′-triiodothyronine. J Biol Chem 267:12539-12544
36. Goswami A, Rosenberg IN 1987 Thioredoxin stimulates enzymatic outer ring monodeiodination of reverse triiodothyronine. Endocrinology 121:1937-1945
37. m iodothyronine 5′-deiodinase. Biochem J 258:785-792
38. Goswami A, Rosenberg IN 1983 Stimulation of iodothyronine outer ring monodeiodinase by dihydrolipoamide. Endocrinology 112:1180-1187
39. Sawada K, Hummel BCW, Walfish PG 1985 Cytosolic cofactors and dihydrolipoamide stimulate hepatic microsomal 5′-deiodination. Endocrinology 117:1259-1263
40. r cytosolic components potentiate hepatic 5′-deiodinase activation by thiols. Biochem J 238:787-791
41. Lamoureux GV, Whitesides GM 1993 Synthesis of dithiols as reducing agents for disulfides in neutral aqueous solution and comparison of reduction potentials. J Org Chem 58:633-641
42. Mugesh G, Klotz L-O, du Mont W-W, Becker K, Sies H 2003 Selenenyl iodide: a new substrate for mammalian thioredoxin reductase. Org Biomol Chem 1:2848-2852
43. Orozco A, Villalobos P, Jeziorski MC, Valverde-RC 2003 The liver of Fundulus heteroclitus expresses deiodinase type 1 mRNA. Gen Comp Endocrinol 130:84-91
44. Cyr DG, Idler DR, Audet C, McLeese JM, Eales JG 1998 Effects of long-term temperature acclimation on thyroid hormone deiodinase function, plasma thyroid hormone levels, growth, and reproductive status of male Atlantic cod, Gadus morhua. Gen Comp Endocrinol 109:24-36
45. m outer-ring deiodination in red drum (Sciaenops ocellatus). Comp Biochem Physiol B Biochem Mol Biol 128:413-423
46. Visser TJ, Kaptein E, Aboul-Enein HY 1992 Selenouracil derivatives are potent inhibitors of the selenoenzyme type I iodothyronine deiodinase. Biochem Biophys Res Commun 189:1362-1367
47. Lian G, Ding L, Chen M, Liu Z, Zhao D, Ni J 2001 Preparation and properties of a selenium-containing catalytic antibody as type I deiodinase mimic. J Biol Chem 276:28037-28041
48. Berry MJ, Banu L, Larsen PR 1991 Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature 349:438-440
49. Mandel SJ, Berry MJ, Kieffer JD, Harney JW, Warne RL, Larsen PR 1992 Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase. J Clin Endocrinol Metab 75:1133-1139
50. Maia AL, Berry MJ, Sabbag R, Harney JW, Larsen PR 1995 Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency. Mol Endocrinol 9:969-980
51. Leonard JL, Visser TJ, Leonard DM 2001 Characterization of the subunit structure of the catalytically active type I iodothyronine deiodinase. J Biol Chem 276:2600-2607
52. Jayasinghe S, Hristova K, White SH 2001 Energetics, stability, and prediction of transmembrane helices. J Mol Biol 312:927-934