Molecular Basis for the Substrate Selectivity of Cat Type I Iodothyronine Deiodinase

Endocrinology

Volumn 144, Issue 12, 2003, Pages 5411-5421

  Kuiper, George G J M ^a   Wassen, Frank ^a   Klootwijk, Willem ^a   Van Toor, Hans ^a   Kaptein, Ellen ^a   Visser, Theo J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; LIOTHYRONINE; SELENOPROTEIN; THYROXINE; TYPE 1 IODOTHYRONINE DEIODINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAT; CATALYSIS; CATALYST; CONTROLLED STUDY; DEIODINATION; DNA FLANKING REGION; GENE INSERTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER MICROSOME; MICHAELIS CONSTANT; MOLECULAR DYNAMICS; MUTAGENESIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; RAT; SPECIES COMPARISON; SULFATION; VELOCITY;

ADULT; AMINO ACID SEQUENCE; ANIMALS; CATS; CLONING, MOLECULAR; DOGS; HUMANS; IODIDE PEROXIDASE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RATS; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; SWINE; THYROID GLAND; TRIIODOTHYRONINE;

EID: 0344825813     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0728     Document Type: Article

References (54)

1. Darras VM, Hume R, Visser TJ 1999 Regulation of thyroid hormone metabolism during fetal development. Mol Cell Endocrinol 151:37-47
2. Köhrle J 2002 Iodothyronine deiodinases. Methods Enzymol 347:125-167
3. Bianco AC, Salvatore D, Gereben B, Berry ML, Larsen PR 2002 Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine deiodinases. Endocr Rev 23:38-89
4. van Doorn J, van der Heide D, Roelfsema F 1983 Sources and quantity of 3,5,3′-triiodothyronine in several tissues of the rat. J Clin Invest 72:1778-1792
5. Nguyen TT, Chapa F, DiStefano III JJ 1998 Direct measurement of the contributions of type I and type II 5′-deiodinases to whole body steady state 3, 5, 3′-triiodothyronine production from thyroxine in the rat. Endocrinology 139: 4626-4633
6. Berry MJ, Banu L, Larsen PR 1991 Type I iodothyronine deiodinase is a selenocysteine containing enzyme. Nature 349:438-440
7. Moreno M, Berry MJ, Horst C, Thoma R, Coglia F, Harney JW, Larsen PR, Visser TJ 1994 Activation and inactivation of thyroid hormone by type I iodothyronine deiodinase. FEBS Lett 344:143-146
8. Visser TJ, Fekkes D, Docter R, Hennemann G 1978 Sequential deiodination of thyroxine in rat liver homogenate. Biochem J 174:221-229
9. Schoenmakers CHH, Pigmans IGAJ, Visser TJ 1992 Species differences in liver type I iodothyronine deiodinase. Biochim Biophys Acta 1121:160-166
10. Köhrle J, Rasmussen UB, Ekenbarger DM, Alex S, Rokos H, Hesch RD, Leonard JL 1990 Affinity labeling of rat liver and kidney type I deiodinase. J Biol Chem 265:6155-6163
11. Safran M, Leonard JL 1991 Comparison of the physicochemical properties of type I and type II iodothyronine 5′-deiodinase. J Biol Chem 266:3233-3238
12. Leonard JL, Visser TJ, Leonard DB 2001 Characterization of the subunit structure of catalytically active type I iodothyronine deiodinase. J Biol Chem 276:2600-2607
13. Curcio-Morelli C, Gereben B, Zavacki A, Kim BW, Huang S, Harney JW, Larsen PR, Bianco AC 2003 In vivo dimerization of types 1, 2 and 3 iodothyronine selenodeiodinases. Endocrinology 144:937-946
14. Leonard JL, Rosenberg IN 1978 Subcellular distribution of thyroxine 5′-deiodinase in the rat kidney: a plasma membrane location. Endocrinology 103: 274-280
15. Leonard JL, Ekenbarger DM, Frank SJ, Farwell AP, Köhrle J 1991 Localization of type I iodothyronine 5′-deiodinase to the basolateral plasma membrane in renal cortical epithelial cells. J Biol Chem 266:11262-11269
16. Fekkes D, van Overmeeren-Kaptein E, Docter R, Hennemann G, Visser TJ 1979 Location of rat liver iodothyronine deiodinating enzymes in the endoplasmic reticulum. Biochim Biophys Acta 587:12-19
17. Auf Dem Brinke D, Hesch RD, Köhrle J 1979 Re-examination of the subcellular localization of thyroxine 5′-deiodination in rat liver. Biochem J 180:273-279
18. Baqui MM, Gereben B, Harney JW, Larsen PR, Bianco AC 2000 Distinct subcellular localization of transiently expressed types 1 and 2 iodothyronine deiodinases as determined by immunofluorescence confocal microscopy. Endocrinology 141:4309-4312
19. Berry MJ, Maia AL, Kieffer JD, Harney JW, Larsen PR 1992 Substitution of cysteine for selenocysteine in type I iodothyronine deiodinase reduces the catalytic efficiency of the protein but enhances its translation. Endocrinology 131:1848-1852
20. Berry MJ, Kieffer JD, Harney JW, Larsen PR 1991 Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase. J Biol Chem 266:14155-14158
21. Mandel SJ, Berry M, Kieffer JD, Harney JW, Warne RL, Larsen PR 1992 Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase. J Clin Endocrinol Metab 75:1133-1139
22. Toyoda N, Harney JW, Berry MJ, Larsen PR 1994 Identification of critical amino acids for 3, 3′, 5′-triiodothyronine deiodination by human type I deiodinase based on comparative functional-structural analysis of the human, dog and rat enzymes. J Biol Chem 269:20329-20334
23. van der Geyten S, Sanders J, Kaptein E, Darras VM, Kuhn ER, Leonard JL, Visser TJ 1997 Expression of chicken hepatic type I and III iodothyronine deiodinases during embryonic development. Endocrinology 138:5144-5152
24. Sanders JP, van der Geyten S, Kaptein E, Darras VM, Kühn ER, Leonard JL, Visser TJ 1997 Characterization of a propylthiouracil-insensitive type I iodothyronine deiodinase. Endocrinology 138:5153-5160
25. Orozco A, Villalobos P, Jeziorski MC, Valverde-R C 2003 The liver of Fundulus heteroclitus expresses deiodinase type I mRNA. Gen Comp Endocrinol 130:84-91
26. Toyoda N, Berry MJ, Harney JW, Larsen PR 1995 Topological analysis of the integral membrane protein, type I iodothyronine deiodinase. J Biol Chem 270:12310-12318
27. Mol JA, Docter R, Hennemann G, Visser TJ 1984 Modification of rat liver 5′-deiodinase activity with diethylpyrocarbonate and rose bengal: evidence for an active site histidine residue. Biochem Biophys Res Commun 120:28-36
28. Berry MJ 1992 Identification of essential histidine residues in rat type I iodothyronine deiodinase. J Biol Chem 267:18055-18059
29. Laurberg P, Boye N 1982 Outer and inner ring monodeiodination of thyroxine by dog thyroid and liver: a comparative study using a particulate cell fraction. Endocrinology 110:2124-2130
30. Toyoda N, Kaptein E, Berry MJ, Harney JW, Larsen PR, Visser TJ 1997 Structure-activity relationships for thyroid hormone deiodination by mammalian type I iodothyronine deiodinases. Endocrinology 138:213-219
31. Foster DJ, Thoday KL, Beckett GJ 2000 Thyroid hormone deiodination in the domestic cat. J Mol Endocrinol 24:119-126
32. Yu S, Howard KA, Wedekind KJ, Morris JG, Rogers QR 2002 A low-selenium diet increases thyroxine and decreases 3, 5, 3′-triiodothyronine in the plasma of kittens. J Anim Physiol Anim Nutr 86:36-41
33. Visser TJ, Docter R, Hennemann G 1977 Radioimmunoassay of reverse-triiodothyronine. J Endocrinol 73:395-396
34. Mol JA, Visser TJ 1985 Synthesis and some properties of sulfate esters and sulfamates of iodothyronines. Endocrinology 117:1-7
35. Mol JA, Docter R, Kaptein E, Jansen G, Hennemann G, Visser TJ 1984 Inactivation and affinity-labeling of rat liver iodothyronine deiodinase with N-bromo-acetyl-3, 3′, 5-triiodothyronine. Biochem Biophys Res Commun 124: 475-483
36. Visser TJ, Kaptein E, Terpstra OT, Krenning EP 1988 Deiodination of thyroid hormone by human liver. J Clin Endocrinol Metab 67:17-23
37. Kuiper GGJM, Klootwijk W, Visser TJ 2002 Substitution of cysteine for a conserved alanine residue in the catalytic center of type II iodothyronine deiodinase alters interaction with reducing cofactor. Endocrinology 143:1190-1198
38. Kuiper GGJM, Klootwijk W, Visser TJ 2003 Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference. Endocrinology 144:2505-2513
39. Sambrook J, Russell DW 2001 In vitro mutagenesis using double-stranded DNA templates: selection of mutants with Dpn I. In: Molecular cloning, a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 13.19-13.25
40. Parikh A, Guengerich FP 1998 Random mutagenesis by whole-plasmid PCR amplification. Biotechniques 24:428-431
41. Kaptein EM, Hays MT, Ferguson DC 1994 Thyroid hormone metabolism - a comparative evaluation. Vet Clin North Am Small Anim Pract 24:431-466
42. Otten MH, Mol JA, Visser TJ 1983 Sulfation preceding deiodination of iodothyronines in rat hepatocytes. Science 221:81-83
43. Visser TJ 1994 Sulfation and glucuronidation pathways of thyroid hormone metabolism. In: Wu S-Y, Visser TJ, eds. Thyroid hormone metabolism: molecular biology and alternate pathways. Boca Raton, FL: CRC Press; pp 85-117
44. Beckett GJ, Beddows SE, Morrice PC, Nicol F, Arthur JR 1987 Inhibition of hepatic deiodination of thyroxine is caused by selenium deficiency in rats. Biochem J 248:443-447
45. Behne D, Kyriakopoulos A, Meinhold H, Kohrle J 1990 Identification of type I iodothyronine 5′-deiodinase as a selenoenzyme. Biochem Biophys Res Commun 173:1143-1149
46. DePalo D, Kinlaw WB, Zhao C, Engelberg-Kulka H, St Germain DL 1994 Effect of selenium deficiency on type I 5′-deiodinase. J Biol Chem 269:16223-16228
47. Rester MHA, Kaptein E, Roest TJ, van Dijk C, Tibboel D, Meinl W, Glatt H, Coughtrie MWH, Visser TJ 1999 Characterization of human iodothyronine sulfotranserases. J Clin Endocrinol Metab 84:1357-1364
48. Kester MHA, Kaptein E, van Dijk C, Roest TJ, Tibboel D, Coughtie MWH, Visser TJ 2002 Characterization of iodothyronine sulfatase activities in human and rat liver and placenta. Endocrinology 143:814-819
49. Kohrle J, Auf'mkolk M, Rokos H, Hesch R-D, Cody V 1986 Rat liver iodothyronine monodeiodinase - evaluation of the iodothyronine ligand-binding site. J Biol Chem 261:11613-11622
50. Okabe N, Fujiwara T, Yamagata Y, Tomita K 1982 The crystal structure of a major metabolite of thyroid hormone: 3, 3′, 5′-triiodo-L- thyronine. Biochim Biophys Acta 717:179-181
51. Visser TJ, Fekkes D, Docter R, Hennemann G 1979 Kinetics of enzymic reductive deiodination of iodothyronines. Biochem J 179:489-495
52. Fekkes D, Hennemann G, Visser TJ 1982 Evidence for a single enzyme in rat liver catalysing the deiodination of the tyrosyl and the phenolic ring of iodothyronines. Biochem J 201:673-676
53. Heinen E, Basler M, Herrmann J, Hafner D, Kruskemper HL 1980 Enzyme kinetic and substrate-binding studies of the thyroxine to 3, 5, 3′-triiothyronine convertin enzyme in the rat liver microsomal fraction. Endocrinology 107:1198-1204
54. Visser TJ 1994 Role of sulfation in thyroid hormone metabolism. Chem Biol Interact 92:293-303