Endogenous γ-aminobutyric acid can excite gonadotropin-releasing hormone neurons

Endocrinology

Volumn 146, Issue 12, 2005, Pages 5374-5379

  Moenter, Suzanne M ^a   DeFazio, R Anthony ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; GLUTAMATE RECEPTOR; GONADORELIN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DIESTRUS; FEMALE; FERTILITY; GABAERGIC TRANSMISSION; MOUSE; NERVE CELL NETWORK; NERVE CELL STIMULATION; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRENATAL PERIOD; PRIORITY JOURNAL;

ACTION POTENTIALS; ANDROGENS; ANIMALS; DIESTRUS; DIHYDROTESTOSTERONE; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GONADOTROPIN-RELEASING HORMONE; HYPOTHALAMUS; MICE; MICE, TRANSGENIC; NERVE NET; NEURONS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RECEPTORS, GABA-A; RECEPTORS, GLUTAMATE; SYNAPTIC TRANSMISSION;

EID: 27844478202     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-0788     Document Type: Article

References (58)

1. Leranth C, MacLusky NJ, Sakamoto H, Shanabrough M, Naftolin F 1985 Glutamic acid decarboxylase-containing axons synapse on LHRH neurons in the rat medial preoptic area. Neuroendocrinology 40:536-539
2. Jansen HT, Cutter C, Hardy S, Lehman MN, Goodman RL 2003 Seasonal plasticity within the GnRH system of the ewe: changes in identified GnRH inputs and in glial association. Endocrinology 144:3663-3676
3. Pompolo S, Pereira A, Kaneko T, Clarke IJ 2003 Seasonal changes in the inputs to gonadotropin-releasing hormone neurons in the ewe brain: an assessment by conventional fluorescence and confocal microscopy. J Neuroendocrinol 15:538-545
4. Pape JR, Skynner MJ, Sim JA, Herbison AE 2001 Profiling γ-aminobutyric acid (GABAA) receptor subunit mRNA expression in postnatal gonadotropinreleasing hormone (GnRH) neurons of the male mouse with single cell RTPCR. Neuroendocrinology 74:300-308
5. A receptor subunits are expressed in LHRH neurons of juvenile female rats. Brain Res 780:218-229
6. Smith MJ, Jennes L 2001 Neural signals that regulate GnRH neurons directly during the oestrous cycle. Reproduction 122:1-10
7. Spergel DJ, Kruth U, Hanley DF, Sprengel R, Seeburg PH 1999 GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic mice. J Neurosci 19:2037-2050
8. A receptor signalling in native GnRH neurons. Eur J Neurosci 12:3497-3504
9. Sullivan SD, Moenter, SM 2005 GABAergic integration of progesterone and androgen feedback to gonadotropin-releasing hormone neurons. Biol Reprod 72:33-41
10. Sullivan SD, Moenter SM 2004 Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorder. Proc Natl Acad Sci USA 101:7129-7134
11. Sullivan SD, Moenter SM 2004 γ-Aminobutyric acid neurons integrate and rapidly transmit permissive and inhibitory metabolic cues to gonadotropinreleasing hormone neurons. Endocrinology 145:1194-1202
12. Jarry H, Perschl A, Wuttke W 1988 Further evidence that preoptic anterior hypothalamic GABAergic neurons are part of the GnRH pulse and surge generator. Acta Endocrinol (Copenh) 118:573-579
13. Robinson J, Kendrick K, Lambart C 1991 Changes in the release of γ-aminobutyric acid and catecholamines in the preoptic/septal area prior to and during the preovulatory surge of luteinizing hormone in the ewe. J Neuroendocrinol 3:393-399
14. Herbison AE, Dyer RG 1991 Effect on luteinizing hormone secretion of GABA receptor modulation in the medial preoptic area at the time of proestrous luteinizing hormone surge. Neuroendocrinology 53:317-320
15. Terasawa E, Luchansky LL, Kasuya E, Nyberg CL 1999 An increase in glutamate release follows a decrease in γ aminobutyric acid and the pubertal increase in luteinizing hormone releasing hormone release in the female rhesus monkeys. J Neuroendocrinol 11:275-282
16. A receptor-mediated control of luteinizing hormone secretion in immature male rats. Brain Res 748:258-262
17. Bilger M, Heger S, Brann DW, Paredes A, Ojeda SR 2001 A conditional tetracycline-regulated increase in γ amino butyric acid production near luteinizing hormone-releasing hormone nerve terminals disrupts estrous cyclicity in the rat. Endocrinology 142:2102-2114
18. Donoso AO, Lopez FJ, Negro-Vilar A 1992 Cross-talk between excitatory and inhibitory amino acids in the regulation of luteinizing hormone-releasing hormone secretion. Endocrinology 131:1559-1561
19. Feleder C, Jarry H, Leonhardt S, Wuttke W, Moguilevsky JA 1996 The GABAergic control of gonadotropin-releasing hormone secretion in male rats during sexual maturation involves effects on hypothalamic excitatory and inhibitory amino acid systems. Neuroendocrinology 64:305-312
20. Han SK, Abraham IM, Herbison AE 2002 Effect of GABA on GnRH neurons switches from depolarization to hyperpolarization at puberty in the female mouse. Endocrinology 143:1459-1466
21. DeFazio RA, Heger S, Ojeda SR, Moenter SM 2002 Activation of A-type γ-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons. Mol Endocrinol 16:2872-2891
22. A receptor channel function in the nervous system. Prog Neurobiol 42:489-537
23. Gulledge AT, Stuart GJ 2003 Excitatory actions of GABA in the cortex. Neuron 37:299-309
24. Wagner S, Castel M, Gainer H, Yarom Y 1997 GABA in the mammalian suprachiasmatic nucleus and its role in diurnal rhythmicity. Nature 387:598-603
25. A receptor-mediated responses in spinal neurons. J Neurosci 16:82-91
26. Lowe G, Gold GH 1993 Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells. Nature 366:283-286
27. Kurahashi T, Yau KW 1993 Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells. Nature 363:71-74
28. Miller RF, Dacheux RF 1983 Intracellular chloride in retinal neurons: measurement and meaning. Vis Res 23:399-411
29. Gallagher JP, Nakamura J, Shinnick-Gallagher P 1983 The effects of temperature, pH and Cl-pump inhibitors on GABA responses recorded from cat dorsal root ganglia. Brain Res 267:249-259
30. Han SK, Todman MG, Herbison AE 2004 Endogenous GABA release inhibits the firing of adult gonadotropin-releasing hormone neurons. Endocrinology 145:495-499
31. Salazar P, Tapia R, Rogawski MA 2003 Effects of neurosteroids on epileptiform activity induced by picrotoxin and 4-aminopyridine in the rat hippocampal slice. Epilepsy Res 55:71-82
32. Feng Z, Durand DM 2005 Decrease in synaptic transmission can reverse the propagation direction of epileptiform activity in hippocampus in vivo. J Neurophysiol 93:1158-1164
33. Zappone CA, Sloviter RS 2004 Translamellar disinhibition in the rat hippocampal dentate gyrus after seizure-induced degeneration of vulnerable hilar neurons. J Neurosci 24:853-864
34. Suter KJ, Song WJ, Sampson TL, Wuarin JP, Saunders JT, Dudek FE, Moenter SM 2000 Genetic targeting of green fluorescent protein to gonadotropinreleasing hormone neurons: characterization of whole-cell electrophysiological properties and morphology. Endocrinology 141:412-419
35. Chu Z, Moenter SM 2005 Endogenous activation of metabotropic glutamate receptors modulates GABAergic transmission to gonadotropin-releasing hormone neurons and alters their firing rate: a possible local feedback circuit. J Neurosci 25:5740-5749
36. Nunemaker CS, DeFazio RA, Moenter SM 2002 Estradiol-sensitive afferents modulate long-term episodic firing patterns of GnRH neurons. Endocrinology 143:2284-2292
37. Nunemaker CS, DeFazio, RA, Moenter SM 2003 A targeted extracellular approach for recording long-term firing patterns of excitable cells: a practical guide. Biol Proc Online 5:53-62
38. Paxinos G, Franklin K 2001 The mouse brain in stereotaxic coordinates. 2nd ed. New York: Academic Press
39. Sullivan SD, DeFazio RA, Moenter SM 2003 Metabolic regulation of fertility through presynaptic and postsynaptic signaling to gonadotropin- releasing hormone neurons. J Neurosci 23:8578-8585
40. Teshima K, Kim SH, Allen CN 2003 Characterization of an apamin-sensitive potassium current in suprachiasmatic nucleus neurons. Neuroscience 120:65-73
41. Hablitz JJ 1984 Picrotoxin-induced epileptiform activity in hippocampus: role of endogenous versus synaptic factors. J Neurophysiol 51:1011-1027
42. Suter KJ 2004 Control of firing by small (S)-α-amino-3-hydroxy-5- methylisoxazolepropionic acid-like inputs in hypothalamic gonadotropin releasinghormone (GnRH) neurons. Neuroscience 128:443-450
43. Herbison AE 1998 Multimodal influence of estrogen upon gonadotropinreleasing hormone neurons. Endocr Rev 19:302-330
44. Terasawa E 1998 Cellular mechanism of pulsatile LHRH release. Gen Comp Endocrinol 112:283-295
45. Waltz W, Boulton AA, Baker GB 2002 Patch-clamp analysis: advanced techniques. Totowa, NJ: Humana Press
46. Sakman B, Neher E 1995 Single-channel recording. 2nd ed. New York: Plenum Press
47. Sim JA, Skynner MJ, Herbison AE 2001 Heterogeneity in the basic membrane properties of postnatal gonadotropin-releasing hormone neurons in the mouse. J Neurosci 21:1067-1075
48. Glitsch M, Marty A 1999 Presynaptic effects of NMDA in cerebellar Purkinje cells and interneurons. J Neuorsci 19:511-519
49. Brambilla D, Chapman D, GreeneR2005 Adenosine mediation of presynaptic feedback inhibition of glutamate release. Neuron 46:275-283
50. Goodman RL, Knobil E 1981 The sites of action of ovarian steroids in the regulation of LH secretion. Neuroendocrinology 32:57-63
51. Moenter SM, Caraty A, Locatelli A, Karsch FJ 1991 Pattern of gonadotropinreleasing hormone (GnRH) secretion leading up to ovulation in the ewe: existence of a preovulatory GnRH surge. Endocrinology 129:1175-1182
52. Leipheimer RE, Bona-Gallo A, Gallo RV 1984 The influence of progesterone and estradiol on the acute changes in pulsatile luteinizing hormone release induced by ovariectomy on diestrous day 1 in the rat. Endocrinology 114:1605-1612
53. Schreihofer DA, Parfitt DB, Cameron JL 1993 Suppression of luteinizing hormone secretion during short-term fasting in male rhesus monkeys: the role of metabolic versus stress signals. Endocrinology 132:1881-1889
54. Wade GN, Schneider JE 1992 Metabolic fuels and reproduction in female mammals. Neurosci Biobehav Rev 16:235-272
55. Pielecka J, Quaynor SD, Moenter SM, Androgens interfere with the ability of progesterone to reduce activity of GnRH neurons. Program of the 87th Annual Meeting of The Endocrine Society, San Francisco, CA, 2005, p 188 (Abstract P1-87)
56. Koch C, Poggio T, Torre V 1983 Nonlinear interactions in a dendritic tree: localization, timing, and role in information processing. Proc Natl Acad Sci USA 80:2799-2802
57. A receptor-mediated postsynaptic conductance. J Neurophysiol 68:197-212
58. Marty A, Llano I 2005 Excitatory actions of GABA in established brain networks. Trends Neurosci 28:284-289