Estradiol-sensitive afferents modulate long-term episodic firing patterns of GnRH neurons

Endocrinology

Volumn 143, Issue 6, 2002, Pages 2284-2292

  Nunemaker, Craig S ^a   Anthony Defazio, R ^a   Moenter, Suzanne M ^a,b  

^a NATIONAL SCIENCE FOUNDATION   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ESTRADIOL; GLUTAMATE RECEPTOR; GONADORELIN; GREEN FLUORESCENT PROTEIN;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; FEEDBACK SYSTEM; FERTILITY; HORMONAL REGULATION; MALE; MOUSE; NONHUMAN; OVARIECTOMY; PATTERN GENERATOR; PREOPTIC AREA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BLOCKING; SENSORY NERVE; SINGLE UNIT ACTIVITY; TRANSGENIC MOUSE;

EID: 0036090391     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.143.6.8869     Document Type: Article

References (60)

1. Ovarian steroids and the brain: Implications for cognition and aging
2. The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized ewes
3. In vivo gonadotropin-releasing hormone release and serum luteinizing hormone measurements in ovariectomized, estrogen-treated rhesus macaques
4. Pattern of gonadotropin-releasing hormone (GnRH) secretion leading up to ovulation in the ewe: Existence of a preovulatory GnRH surge
5. Neuroendocrine regulation of the luteinizing hormone-releasing hormone pulse generator in the rat
6. Is there an FSH-releasing factor?
7. Hypophysial responses to continuous and intermittent delivery of hypothalamic gonadotropin-releasing hormone
8. The role of changing pulse frequency in the regulation of ovulation
9. Luteinizing hormone releasing factor in pituitary stalk plasma from long-term ovariectomized rats: Effects of steroids
10. Steroid feedback inhibition of pulsatile secretion of gona dotropin-releasing hormone in the ewe
11. Unexpected responses of the hypothalamic gonadotropin-releasing hormone "pulse generator" to physiological estradiol inputs in the absence of the ovary
12. Chronic recording of electrophysiological manifestation of the hypothalamic gonadotropin-releasing hormone pulse generator activity in the goat
13. Central regulation of pulsatile gonadotropin-releasing hormone (GnRH) secretion by estradiol during the period leading up to the preovulatory GnRH surge in the ewe
14. Acute estradiol modulation of electrical activity of the LHRH pulse generator in the ovariectomized rat: Restoration by naloxone
15. Absence of oestradiol concentration in cell nuclei of LHRH-immunoreactive neurones
16. Localization of oestrogen receptors in preoptic neurons containing neurotensin but not tyrosine hydroxylase, cholecystokinin or luteinizing hormone-releasing hormone in the male and female rat
17. Do gonadotropin-releasing hormone, tyrosine hydroxylase-, and β-endorphin-immunoreactive neurons contain estrogen receptors? A double-label immunocytochemical study in the Suffolk ewe
18. Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons
19. Detection of estrogen receptor α and β messenger ribonucleic acids in adult gonadotropin-releasing hormone neurons
20. Estrogen receptor-β immunoreactivity in luteinizing hormone-releasing hormone neurons of the rat brain
21. GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic mice
22. Genetic targeting of green fluorescent protein to gonadotropin-releasing hormone neurons: Characterization of whole-cell electrophysiological properties and morphology
23. Whole-cell recordings from preoptic/hypothalamic slices reveal burst firing in gonadotropin-releasing hormone neurons identified with green fluorescent protein in transgenic mice
24. Glutamate, the dominant excitatory transmitter in neuroendocrine regulation
25. GABA: A dominant neurotransmitter in the hypothalamus
26. Cluster analysis: A simple, versatile, and robust algorithm for endocrine pulse detection
27. Long-term recordings of networks of immortalized GnRH neurons reveal episodic patterns of electrical activity
28. A supersensitive immunofluorometric assay for rat luteinizing hormone
29. Impact of uremia on female reproductive cyclicity, ovulation, and luteinizing hormone in the rat
30. Electrophysiology of hypothalamic magnocellular neurones secreting oxytocin and vasopressin
31. Phytoestrogens and gonadotropin-releasing hormone pulse generator activity and pituitary luteinizing hormone release in the rat
32. Identification of estrogen-responsive LHRH neurons in the guinea pig hypothalamus
33. Estradiol-17β and mu-opioid peptides rapidly hyperpolarize GnRH neurons: A cellular mechanism of negative feedback?
34. Ultrastructural characterization of gonadotropin-releasing hormone (GnRH)-producing neurons
35. Immortalized gonadotropin-releasing hormone neurons secrete γ-aminobutyric acid-evidence for an autocrine regulation
36. Expression of γ-aminobutyric acid and gonadotropin-releasing hormone during neuronal migration through the olfactory system
37. Evidence for estrogen-receptive GABAergic neurons in the preoptic/anterior hypothalamic area of the rat brain
38. In vivo GABA release from the medial preoptic area of diestrous and ovariectomized rats
39. Release of glutamate and aspartate from the preoptic area during the progesterone-induced LH surge: In vivo microdialysis studies
40. Preoptic rather than mediobasal hypothalamic amino acid neurotransmitter release regulates GnRH secretion during the estrogen-induced LH surge in the ovariectomized rat
41. Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat
42. Rapid action of 17β-estradiol on kainate-induced currents in hippocampal neurons lacking intracellular estrogen receptors
43. Excitatory amino acids: Function and significance in reproduction and neuroendocrine regulation
44. A subset of gonadotropin-releasing hormone neurons in the ovine medial basal hypothalamus is activated during increased pulsatile luteinizing hormone secretion
45. Heterogeneity in the basic membrane properties of postnatal gonadotropin-releasing hormone neurons in the mouse
46. Currents evoked by GABA and glycine in acutely dissociated neurons from the rat medial preoptic nucleus
47. Mandatory neuropeptide-steroid signaling for the preovulatory luteinizing hormone-releasing hormone discharge
48. New concepts of the neuroendocrine regulation of gonadotropin surges in rats
49. Co-expression of steroid hormone receptors in opioid peptide-containing neurons correlates with patterns of gene expression during the estrous cycle
50. Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis
51. Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons
52. Generation and synchronization of gonadotropin-releasing hormone (GnRH) pulses: Intrinsic properties of the GT1-1 GnRH neuronal cell line
53. Cycles of transcription and translation do not comprise the gonadotropin-releasing hormone pulse generator in GT1 cells
54. Synchronized exocytotic bursts from gonadotropin-releasing hormone-expressing cells: Dual control by intrinsic cellular pulsatility and gap junctional communication
55. Episodic bursting activity and response to excitatory amino acids in acutely dissociated gonadotropin-releasing hormone neurons genetically targeted with green fluorescent protein
56. 2+ oscillations in luteinizing hormone-releasing hormone neurons derived from the embryonic olfactory placode of the rhesus monkey
57. Estradiol and the inhibition of hypothalamic gonadotropin-releasing hormone pulse generator activity in the rhesus monkey
58. Neuroendocrine basis of seasonal reproduction
59. Puberty in the rat