Hypophosphoric acid is a unique substrate of pyrophosphorolysis catalyzed by HIV-1 reverse transcriptase

Biochemical and Biophysical Research Communications

Volumn 338, Issue 3, 2005, Pages 1335-1341

  Kukhanova, Marina K ^a   Zakirova, Natalia F ^a   Ivanov, Alexander V ^a,b   Alexandrova, Ludmila A ^a   Jasco, Maxim V ^a   Khomutov, Alex R ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

HIV 1 reverse transcriptase; Kinetics; Klenow fragment; Pyrophosphate analogues; Pyrophosphorolysis

Indexed keywords

PHOSPHORIC ACID DERIVATIVE; PHOSPHORUS DERIVATIVE; RNA DIRECTED DNA POLYMERASE; THYMIDINE PHOSPHATE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; PRIORITY JOURNAL; PYROLYSIS; PYROPHOSPHOROLYSIS; REACTION ANALYSIS; SYNTHESIS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 27744599638     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.10.092     Document Type: Article

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