Genetic approaches to the study of aging

Journal of the American Geriatrics Society

Volumn 53, Issue 9 SUPPL., 2005, Pages

  Miller, Richard A ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Genetics; IGF I; Longevity; Mice; Mutations

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; DNA REPAIR; GENETIC TRAIT; GENETIC VARIABILITY; HORMONE DETERMINATION; LIFESPAN; LONGEVITY; MEDICAL RESEARCH; MOUSE; NONHUMAN; ANIMAL; DISEASE MODEL; DRUG DESIGN; DRUG EFFECT; GENETICS; HEALTH; HUMAN; PHYSIOLOGY; PREVENTIVE MEDICINE;

SOMATOMEDIN C;

AGING; ANIMALS; CALORIC RESTRICTION; DISEASE MODELS, ANIMAL; DRUG DESIGN; HEALTH; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MICE; PREVENTIVE MEDICINE;

EID: 27744598238     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2005.53490.x     Document Type: Article

References (7)

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2. Miller RA, Chrisp C, Jackson AU et al. Coordinated genetic control of neoplastic and nonneoplastic diseases in mice. J Gerontol A Biol Sci Med Sci 2002;57:B3-B8.
3. Miller RA, Harper JM, Galecki A, Burke DT. Big mice die young: Early-life body weight predicts longevity in genetically heterogeneous mice. Aging Cell 2002;1:22-29.
4. Miller RA. Kleemeier Award Lecture: Are there genes for aging? J Gerontol Biol Sci 1999;54A:B297-B307.
5. Eigenmann JE, Patterson DF, Froesch ER. Body size parallels insulin-like growth factor I levels but not growth hormone secretory capacity. Acta Endocrinologica 1984;106(4):448-453.
6. Eigenmann JE, Amador A, Patterson DF. Insulin-like growth factor I levels in proportionate dogs, chondrodystrophic dogs and in giant dogs. Acta Endocrinologica 1988;118(1):105-108.
7. Flurkey K, Papaconstantinou J, Miller RA, Harrison DE. Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proceedings of the National Academy of Sciences of the United States of America 2001;98:6736-6741.