Multiple-trait quantitative trait loci analysis using a large mouse sibship

Genetics

Volumn 151, Issue 2, 1999, Pages 785-795

  Jackson, Anne U ^a   Fornés, Alison ^a   Galecki, Andrzej ^a,b   Miller, Richard A ^a,b   Burke, David T ^a,b,c  

^a VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANIMAL CELL; ARTICLE; FEMALE; GENETIC ANALYSIS; GENOTYPE; INBREEDING; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SIBLING; T LYMPHOCYTE;

ANIMALS; CROSSES, GENETIC; FEMALE; GENETICS, POPULATION; HETEROZYGOTE; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PHENOTYPE;

ANIMALIA; RODENTIA;

EID: 0032914704     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. ATCHLEY, W. R., and W. M. FITCH, 1991 Gene trees and the origin of inbred strains of mice. Science 254: 554-558.
2. CHRISP, C. E., P. TURKE, A. LUCIANO, S. SWALWELL, J. PETERSON et al., 1996 Lifespan and pathology in genetically heterogeneous (four-way cross) mice: a new model for aging research. Vet. Pathol. 33: 735-743.
3. CHURCHILL, G. A., and R. W. DOERGE, 1994 Empirical threshold values for quantitative trait mapping. Genetics 138: 963-971.
4. COVELLI, V., D. MOUTON, V. DI MAJO, Y. BOUTHILLIER, C. BANGRAZI et al., 1989 Inheritance of immune responsiveness, life span, and disease incidence in interline crosses of mice selected for high or low multispecific antibody production. J. Immunol. 142: 1224-1234.
5. DIETRICH, W. F., H. KATZ, S. E. LINCOLN, H.-S. SHIN, J. FRIEDMAN et al. 1992 A genetic map of the mouse suitable for typing intraspecific crosses. Genetics 131: 423-447.
6. DIETRICH, W. F., J. C. MILLER, R. G. STEEN, M. MERCHANT, D. DAMRON et al., 1994 A genetic map of the mouse with 4006 simple sequence length polymorphisms. Nat. Genet. 7: 220-245.
7. FRANKEL, W. N., 1995 Taking stock of complex trait genetics in mice. Trends Genet. 11: 471-477.
8. GELMAN, R., A. WATSON, R. BRONSON and E. YUNIS, 1988 Murine chromosomal regions correlated with longevity. Genetics 118: 693-704.
9. HALEY, C. S., and S. A. KNOTT, 1992 A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69: 315-324.
10. JIANG, C., and Z.-B. ZENG, 1995 Multiple trait analysis of genetic mapping for quantitative trait loci. Genetics 140: 1111-1127.
11. JOHNSON, T. E., 1987 Aging can be genetically dissected into component processes using long-lived lines of Caenorhabdilis elegans. Proc. Nad. Acad. Sci. USA 84: 3777-3781.
12. KNOTT, S. A., and C. S. HALEY, 1992 Aspects of maximum likelihood methods for mapping quantitative trait loci in line crosses. Genet. Res. 60: 139-151.
13. KOROL, A. B., Y. I. RONIN and V. M. KIRZHNER, 1995 Interval mapping of quantitative trait loci employing correlated trait complexes. Genetics 140: 1137-1147.
14. LANDER, E. S., and D. BOTSTEIN, 1989 Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121: 185-199.
15. LANDER, E. S., and N. J. SCHORK, 1994 Genetic dissection of complex traits. Science 265: 2037-2048.
16. MILLER, R. A., 1996 Aging and the immune response, pp. 355-392 in Handbook of the Biology of Aging, edited by E. L. SCHNEIDER and J. W. ROWE. Academic Press, San Diego.
17. MILLER, R. A., 1997 Age-related changes in T cell surface markers: a longitudinal analysis in genetically heterogeneous mice. Mech. Ageing Dev. 96: 181-196.
18. MILLER, R. A., P. TURKE, C. CHRISP, J. RUGER, A. LUCIANO et al., 1994 Age-sensitive T cell phenotypes covary in genetically heterogeneous mice and predict early death from lymphoma. J. Gerontol. 49: B255-B262.
19. MILLER, R. A., F. BOOKSTEIN, J. H. VAN DER MEULEN, S. ENGLE, J. KIM et al., 1996 Candidate biomarkers of aging: age-sensitive indices of immune and muscle function co-vary in genetically heterogeneous mice. J. Gerontol. Biol. Sci. 52A: B29-B47.
20. MILLER, R. A., C. CHRISP and A. GALECKI, 1997 CD4 memory T cell levels predict lifespan in genetically heterogeneous mice. FASEB J. 11: 775-783.
21. ROSE, M. R., 1991 Evolutionary Biology of Aging. Oxford University Press, New York.
22. ROWE, L. B., J. H. NADEAU, R. TURNER, W. N. FRANKEL, V. A. LETTS et al., 1994 Maps from two interspecific backcross DNA panels available as a community resource. Mamm. Genome 5: 253-274.
23. SAMBROOK, J., E. F. FRITSCH and T. MANIATIS, 1989 Molecular Cloning: A Laboratory Manual, Ed. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. SOLLER, M. T., T. BRODY and A. GENIZI, 1976 On the power of experimental design for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines. Theor. Appl. Genet. 47: 35-39.
25. XU, S., 1996 Mapping quantitative trait loci using four-way crosses. Genet. Res. 68: 175-181.
26. ZENG, Z.-B., 1994 Precision mapping of quantitative trait loci. Genetics 136: 1457-1468.