FK506 ameliorates spontaneous locomotor activity in collagen-induced arthritis: Implication of distinct effect from suppression of inflammation

International Immunopharmacology

Volumn 5, Issue 3, 2005, Pages 503-510

  Sasakawa, Tatsuya ^a   Sasakawa, Yuka ^a   Ohkubo, Yoshitaka ^a   Mutoh, Seitaro ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Collagen induced arthritis; FK506; Locomotor activity

Indexed keywords

COLLAGEN TYPE 2; METHOTREXATE; TACROLIMUS;

ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; FEMALE; GRIP STRENGTH; HISTOPATHOLOGY; HYPERALGESIA; IMMUNIZATION; INHIBITION KINETICS; LOCOMOTION; MUSCLE STRENGTH; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME;

EID: 15944374309     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2004.10.012     Document Type: Article

References (28)

1. S.E. Gabriel The epidemiology of rheumatoid arthritis Rheum. Dis. Clin. North Am. 27 2001 269 281
2. E.D. Harris Jr. Rheumatoid arthritis: pathophysiology and implications for therapy N. Engl. J. Med. 322 1990 1277 1289
3. J.F. Fries, P. Spitz, R.G. Kraines, and H.R. Holman Measurement of patient outcome in arthritis Arthritis Rheum. 23 1980 137 145
4. L. Kuritzky, and A. Weaver Advances in rheumatology: coxibs and beyond J. Pain Symp. Manag. 25 2003 S6 S20
5. A. Hakkinen, H. Kautiainen, P. Hannonen, J. Ylinen, M. Arkela-Kautiainen, and T. Sokka Pain and joint mobility explain individual subdimensions of the health assessment questionnaire (HAQ) disability index in patients with rheumatoid arthritis Ann. Rheum. Dis. 0 2004 200301993
6. C.K. Cain, J.M. Francis, M.A. Plone, D.F. Emerich, and M.D. Lindner Pain-related disability and effects of chronic morphine in the adjuvant-induced arthritis model of chronic pain Physiol. Behav. 62 1997 199 205
7. H.G. Schaible, A. Ebersberger, and G.S. Von Banchet Mechanisms of pain in arthritis Ann. N.Y. Acad. Sci. 966 2002 343 354
8. A. Hakkinen Effectiveness and safety of strength training in rheumatoid arthritis Curr. Opin. Rheumatol. 16 2004 132 137
9. K. O'Brien, W.K. Essigman, and S. Little A comparison of the effects of tenoxicam and piroxicam on grip strength in patients with rheumatoid arthritis Scand. J. Rheumatol., Suppl. 80 1989 81 85
10. G. Cunnane, K.M. Hummel, U. Muller-Ladner, R.E. Gay, and S. Gay Mechanism of joint destruction in rheumatoid arthritis Arch. Immunol. Ther. Exp. (Warsz) 46 1998 1 7
11. J.M. Grossman, and E. Brahn Rheumatoid arthritis: current clinical and research directions J. Women's Health 6 1997 627 638
12. T. Pincus Long-term outcomes in rheumatoid arthritis Br. J. Rheumatol. 34 1995 59 73
13. J. Latham, and B.D. Davis The socioeconomic impact of chronic pain Disabil. Rehabil. 16 1994 39 44
14. R.W. Millard, N. Wells, and R.W. Thebarge A comparison of models describing reports of disability associated with chronic pain Clin. J. Pain 7 1991 283 291
15. B.S. Webster, and S.H. Snook The cost of 1989 workers' compensation low back pain claims Spine 19 1994 1111 1115 [discussion 1116]
16. A. Rao, C. Luo, and P.G. Hogan Transcription factors of the NFAT family: regulation and function Annu. Rev. Immunol. 15 1997 707 747
17. N. Yoshimura, S. Matsui, T. Hamashima, and T. Oka Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro: II. Inhibition of the production of IL-2 and gamma-IFN, but not B cell-stimulating factor 2 Transplantation 47 1989 356 359
18. S. Sakuma, Y. Kato, F. Nishigaki, T. Sasakawa, K. Magari, and S. Miyata FK506 potently inhibits T cell activation induced TNF-alpha and IL-1beta production in vitro by human peripheral blood mononuclear cells Br. J. Pharmacol. 130 2000 1655 1663
19. S. Sakuma, Y. Higashi, N. Sato, T. Sasakawa, T. Sengoku, and Y. Ohkubo Tacrolimus suppressed the production of cytokines involved in atopic dermatitis by direct stimulation of human PBMC system (comparison with steroids) Int. Immunopharmacol. 1 2001 1219 1226
20. D.E. Furst, K. Saag, M.R. Fleischmann, Y. Sherrer, J.A. Block, and T. Schnitzer Efficacy of tacrolimus in rheumatoid arthritis patients who have been treated unsuccessfully with methotrexate: a six-month, double-blind, randomized, dose-ranging study Arthritis Rheum. 46 2002 2020 2028
21. J.M. Kremer, J.S. Habros, K.S. Kolba, J.L. Kaine, M.A. Borton, and L.J. Mengle-Gaw Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: a six-month, open-label study Arthritis Rheum. 48 2003 2763 2768
22. K. Magari, S. Miyata, Y. Ohkubo, S. Mutoh, and T. Goto Calcineurin inhibitors exert rapid reduction of inflammatory pain in rat adjuvant-induced arthritis Br. J. Pharmacol. 139 2003 927 934
23. T. Honbo, M. Kobayashi, K. Hane, T. Hata, and Y. Ueda The oral dosage form of FK-506 Transplant. Proc. 19 1987 17 22
24. L.O. Randall, and J.J. Selitto A method for measurement of analgesic activity on inflamed tissue Arch. Int. Pharmacodyn. Ther. 111 1957 409 419
25. S. Sakuma, F. Nishigaki, K. Magari, T. Ogawa, S. Miyata, and Y. Ohkubo FK506 is superior to methotrexate in therapeutic effects on advanced stage of rat adjuvant-induced arthritis Inflamm. Res. 50 2001 509 514
26. E.H. Karran, T.J. Young, R.E. Markwell, and G.P. Harper In vivo model of cartilage degradation-effects of a matrix metalloproteinase inhibitor Ann. Rheum. Dis. 54 1995 662 669
27. P.G. Conaghan, and P. Brooks Disease-modifying antirheumatic drugs, including methotrexate, gold, sulfasalazine, antimalarials, and D-penicillamine Curr. Opin. Rheumatol. 8 1996 176 182
28. J.N. Francischi, L.S. Pereira, and M.S. Castro Cyclosporin inhibits hyperalgesia and edema in arthritic rats: role of the central nervous system Braz. J. Med. Biol. Res. 30 1997 101 111