The diagnosis and management of gastro-oesophageal reflux in infants

Early Human Development

Volumn 81, Issue 12, 2005, Pages 1011-1024

  Vandenplas, Yvan ^a,c   Salvatore, Silvia ^a,b   Hauser, Bruno ^a  

^a UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^b UNIVERSITY OF INSUBRIA   (Italy)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Gastro oesophageal reflux; Newborn; Preterm

Indexed keywords

ALGINIC ACID; ALUMINUM HYDROXIDE; ALUMINUM PHOSPHATE; ANTACID AGENT; ANTIARRHYTHMIC AGENT; BACLOFEN; BICARBONATE; CARBONIC ACID; CISAPRIDE; CLARITHROMYCIN; DOMPERIDONE; ERYTHROMYCIN; FAMOTIDINE; GAVISCON; HISTAMINE H2 RECEPTOR ANTAGONIST; ITOPRIDE; MACROLIDE; MAGNESIUM DERIVATIVE; MAGNESIUM HYDROXIDE; MAGNESIUM TRISILICATE; METOCLOPRAMIDE; MOSAPRIDE CITRATE; NIZATIDINE; ONDANSETRON; PROTON PUMP INHIBITOR; PRUCALOPRIDE; RANITIDINE; SODIUM CARBONATE; SUCRALFATE; TEGASEROD; UNINDEXED DRUG;

ABDOMINAL PAIN; ABNORMALLY HIGH SUBSTRATE CONCENTRATION IN BLOOD; ACHLORHYDRIA; AMINOTRANSFERASE BLOOD LEVEL; ANAMNESIS; BEZOAR; BODY POSITION; CARDIOTOXICITY; CARDIOVASCULAR DISEASE; CENTRAL NERVOUS SYSTEM DISEASE; CHOLESTASIS; CLINICAL FEATURE; CLINICAL TRIAL; COLIC; CONFERENCE PAPER; CORRELATION ANALYSIS; DEVELOPMENTAL STAGE; DIAGNOSTIC PROCEDURE; DIARRHEA; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFECT; DRUG FORMULATION; DRUG METABOLISM; ELECTROLYTE BLOOD LEVEL; EXTRAPYRAMIDAL SYNDROME; GALACTORRHEA; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL DISEASE; GASTROINTESTINAL MOTILITY; HEADACHE; HEART ARRHYTHMIA; HEART DISEASE; HEART VENTRICLE FIBRILLATION; HEMATOLOGIC DISEASE; HISTOPATHOLOGY; HUMAN; HYPERTROPHIC PYLORUS STENOSIS; HYPOTENSION; INFANCY; INFANT; INTESTINE FLORA; KIDNEY DISEASE; META ANALYSIS; METHEMOGLOBINEMIA; MILK ALLERGY; MOLECULE; NEUROENDOCRINE DISEASE; NEUROLOGIC DISEASE; NUTRITIONAL DISORDER; PATHOGENESIS; PH; QT PROLONGATION; RICKETS; RISK FACTOR; SALIVATION DISORDER; SECRETION; SEIZURE; SIDE EFFECT; SKIN DISEASE; SURGICAL TECHNIQUE; SYSTEMATIC REVIEW; TORSADE DES POINTES; VOMITING;

ANTACIDS; CISAPRIDE; DOMPERIDONE; ERYTHROMYCIN; GASTRIC MUCOSA; GASTROESOPHAGEAL REFLUX; HISTAMINE H2 ANTAGONISTS; HUMANS; INFANT; INFANT, NEWBORN; METOCLOPRAMIDE; RISK FACTORS;

EID: 27744573360     PISSN: 03783782     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.earlhumdev.2005.10.011     Document Type: Conference Paper

References (78)

1. T.I. Omari, C.P. Barnett, M.A. Benninga, R. Lontis, L. Goodchild, and R.R. Haslam Mechanisms of gastro-oesophageal reflux in preterm and term infants with reflux disease Gut 51 2002 475 479
2. J.Y. Kang, and K.Y. Ho Different prevalences of reflux oesophagitis and hiatus hernia among dyspeptic patients in England and Singapore Eur J Gastroenterol Hepatol 11 1999 845 850
3. I.J. Carre, B.T. Johnston, P.S. Thomas, and P.J. Morrisson Familial hiatal hernia in a large five generation family confirming true autosomal dominant inheritance Gut 45 1999 649 652
4. N.J. Trudgill, K.C. Kapur, and S.A. Riley Familial clustering of reflux symptoms Am J Gastroenterol 94 1999 1172 1178
5. A.J. Cameron, J. Lagergren, and C. Henriksson Gastroesophageal reflux disease in monozygotic and dizygotic twins Gastroenterology 122 2002 55 59
6. F.Z. Hu, R.A. Preston, and J.C. Post Mapping of a gene for severe pediatric gastroesophageal reflux to chromosome 13q14 JAMA 284 2000 325 334
7. S.R. Orenstein, T.M. Shalaby, M.M. Barmada, and D.C. Whitcomb Genetics of gastroesophageal reflux disease: a review J Pediatr Gastroenterol Nutr 34 2002 506 510
8. S.R. Orenstein, D.C. Whitcomb, and M.M. Barmada Challenges of examining complex genetic disorders like GERD J Pediatr Gastroenterol Nutr 41 Suppl 1 2005 S17 S19
9. S. Salvatore, B. Hauser, and Y. Vandenplas The natural course of gastro-oesophageal reflux Acta Paediatr 93 2004 1063 1069
10. S.P. Nelson, E.H. Chen, and G.M. Syniar One year follow-up of symptoms of gastroesophageal reflux during infancy Pediatrics 102 1998 e67
11. B. Mathisen, L. Worall, J. Masel, C. Wall, and R.W. Shepherd Feeding problems in infants with gastro-oesophageal reflux disease: a controlled study J Pediatr Child Health 35 1999 163 169
12. A.B. Hamilton, and L.K. Zeltzer Visceral pain in infants J Pediatr 125 1994 S95 S102 [Suppl]
13. Y. Vandenplas, H. Badriul, M. Verghote, B. Hauser, and L. Kaufman Oesophageal pH monitoring and reflux oesophagitis in irritable infants Eur J Pediatr 163 2004 300 304
14. R.G. Heine, D.J. Cameron, C.W. Chow, D.J. Hill, and A.G. Catto-Smith Esophagitis in distressed infants: poor diagnostic agreement between esophageal pH monitoring and histopathologic findings J Pediatr 140 2002 14 19
15. K. Armstrong, N. Previtera, and R. McCallum Medicalizing normality? Management of irritability in babies Paediatr Child Health 36 2000 301 305
16. M.M. Black, H. Dubowitz, and J. Huctheson A randomized clinical trial of home intervention for children with failure to thrive Pediatrics 95 1995 807 814
17. R.G. Heine, A. Jaquiery, L. Lubitz, D.J. Cameron, and A.G. Catto-Smith Role of gastro-oesophageal reflux in infant irritability Arch Dis Child 73 1995 121 125
18. A. Snel, C.P. Barnett, and T.L. Cresp Behavior and gastroesophageal reflux in the premature neonate J Pediatr Gastroenterol Nutr 30 2000 18 21
19. C.F. Poets Gastroesophageal reflux: a critical review of its role in preterm infants Pediatrics 113 2004 e128 e132
20. C.D. Rudolph Supraesophageal complications of gastroesophageal reflux in children: challenges in diagnosis and treatment Am J Med 115 Suppl3A 2003 150S 156S
21. B. Suys, D. De Wolf, and Y. Vandenplas Bradycardia and gastroesophageal reflux in term and preterm infants: is there any relation? J Pediatr Gastroenterol Nutr 19 1994 187 190
22. Y. Vandenplas, and E. Hassall Mechanisms of gastroesophageal reflux and gastroesophageal reflux disease J Pediatr Gastroenterol Nutr 35 2002 119 136
23. V. Khoshoo, T. Le, R.M. Haydel Jr., L. Landry, and C. Nelson Role of GER in older children with persistent asthma Chest 123 2003 1008 1013
24. P. Ahrens, C. Noll, R. Kitz, P. Willigens, S. Zielen, and D. Hofmann Lipid-laden alveolar macrophages: a useful marker of silent aspiration in children Pediatr Pulmonol 28 1999 83 88
25. Vandenplas Y. Gastro-esophageal reflux in press.
26. W.G. Paterson, and B.W. Murat Combined ambulatory esophageal manometry and dual-probe pH metry in the evaluation of patients with chronic unexplained cough Dig Dis Sci 39 1994 1117 1125
27. G. Bruno, U. Graf, and P. Andreozzi Gastric asthma: an unrecognized disease with an unsuspected frequency J Asthma 36 1999 315 325
28. S. Salvatore, B. Hauser, K. Vandemaele, R. Novario, and Y. Vandenplas Gastroesophageal reflux disease in infants: how much is predictable with questionnaires, pH-metry, endoscopy and histology? J Pediatr Gastroenterol Nutr 40 2005 210 215
29. B.D. Gold, and J.W. Freston Gastroesophageal reflux in children: pathogenesis, prevalence, diagnosis, and role of proton pump inhibitors in treatment Paediatr Drugs 4 2002 673 685
30. H. Kawahara, J. Dent, G. Davidson, and A. Okada Relationship between straining, transient lower esophageal sphincter relaxation, and gastroesophageal reflux in children Am J Gastroenterol 96 2001 2019 2025
31. G.P. Davidson, and T.I. Omari Childhood GERD is a risk factor for GERD in adolescents and young adults: pathophysiological mechanisms of gastroesophageal reflux disease in children Curr Gastroenterol Rep 3 2001 257 262
32. W.R. Treem, P.M. Davis, and J.S. Hyams Gastroesophageal reflux in the older child: presentation, response to treatment and long-term follow-up Clin Pediatr Phila 30 1991 435 440
33. S.P. Nelson, E.H. Chen, G.M. Syniar, and K.K. Christoffel One-year follow-up of symptoms of gastroesophageal reflux during infancy. Pediatric Practice Research Group Pediatrics 102 1998 E67
34. N. Rommel, A.M. Demeyer, L. Feenstra, and G. Veereman-Wauters The complexity of feeding problems in 700 infants and young children presenting to a tertiary care institution J Pediatr Gastroenterol Nutr 37 2003 75 84
35. A.E. Carroll, M.M. Garrison, and D.A. Christakis A systematic review of nonpharmacological and nonsurgical therapies for gastroesophageal reflux in infants Arch Pediatr Adolesc Med 156 2002 109 113
36. S.R. Orenstein Effects on behavior state of prone versus seated positioning for infants with gastroesophageal reflux Pediatrics 85 1990 765 767
37. A.K. Ewer, M.E. James, and J.M. Tobin Prone and left lateral positioning reduce gastro-oesophageal reflux in preterm infants Arch Dis Child Fetal Neonatal Ed 81 1999 F201 F205
38. J.M. Tobin, P. McCloud, and D.J. Cameron Posture and gastro-eosophageal reflux: a case for left lateral positioning Arch Dis Child 76 1997 254 258
39. S.R. Orenstein Effect of nonnutritive sucking on infant gastroesophageal reflux Pediatr Res 24 1988 38 40
40. Y. Vandenplas, J.Z. Lifshitz, S. Orenstein, C.H. Lifschitz, R.W. Shepherd, and Casaubon Nutritional management of regurgitation in infants J Am Coll Nutr 17 1998 308 316
41. J.L. Sutphen, and V.L. Dillard Dietary caloric density and osmolality influence gastroesophageal reflux in infants Gastroenterology 97 1989 601 604
42. T.M. Shalaby, and S.R. Orenstein Efficacy of telephone teaching of conservative therapy for infants with symptomatic gastroesophageal reflux referred by pediatricians to pediatric gastroenterologists J Pediatr 142 2003 57 61
43. G. Iacono, A. Carroccio, F. Cavataio, G. Montalto, I. Kazmierska, and D. Lorello Gastroesophageal reflux and cow's milk allergy in infants: a prospective study J Allergy Clin Immunol 97 1996 822 827
44. R.G. Nielsen, C. Bindeslev-Jensen, Kruse-Andersen, and S. Husby Severe GOR-disease and cow milk hypersensitivity in infants and children: disease association and evaluation of a new challenge procedure J Pediatric Gastroenterol Nutr 39 2004 383 391
45. T. Klemola, T. Vanto, K. Juntunen-Backman, K. Kalimo, R. Korpela, and E. Varjonen Allergy to soy formula and to extensively hydrolyzed whey formula in infants with cow's milk allergy: a prospective, randomized study with a follow-up to the age of 2 years J Pediatr 140 2002 219 224
46. S. Salvatore, and Y. Vandenplas Gastroesophageal reflux and cow milk allergy: is there a link? Pediatrics 110 2002 972 984
47. Y. Vandenplas, I.S. Hachimi, A. Casteels, T. Mahler, and H. Loeb A clinical trial with an "anti-regurgitation" formula Eur J Pediatr 153 1994 419 423
48. W.R. Craig, A. Hanlon-Dearman, C. Sinclair, S. Taback, and M. Moffatt Metoclopramide, thickened feedings, and positioning for gastro-oesophageal reflux in children under two years Cochrane Database Syst Rev 18 4 2004 (Oct) [CD003502]
49. O. Borrelli, G. Salvia, A. Campanozzi, M.T. Franco, F.L. Moreira, and M. Emiliano Use of a new thickened formula for treatment of symptomatic gastrooesophageal reflux in infants Ital J Gastroenterol Hepatol 29 1997 237 242
50. T.G. Wenzl, S. Schneider, F. Scheele, J. Silny, G. Heimann, and H. Skopnik Effects of thickened feeding on gastroesophageal reflux in infants: a placebo-controlled crossover study using intraluminal impedance. Pediatrics 111 2003 e355 e359
51. J. Ramirez-Mayans, L. Palacio-del Carmen, R. Cervantes-Bustamante, N. Mata-Rivera, N. Pina-Romero, and F. Zarate-Mondragon Nutritional management of children with gastroesophageal reflux: a comparison of two different formulas Int Pediatr 18 2003 78 83
52. I. Xinias, N. Mouane, B. Le Luyer, K. Spiroglou, V. Demertzidou, and B. Hauser Cornstarch thickened formula reduces oesophageal acid exposure time in infants Dig Liver Dis 37 2005 23 27
53. S.R. Orenstein, T.M. Shalaby, and P.E. Putnam Thickened feedings as a cause of increased coughing when used as therapy for gastroesophageal reflux in infants J Pediatr 121 1992 913 915
54. D. Bosscher, M. Van Caillie-Bertrand, R. Van Cauwenbergh, and H. Deelstra Availabilities of calcium, iron, and zinc from dairy infant formulas is affected by soluble dietary fibers and modified starch fractions Nutrition 19 2003 641 645
55. P.J. Aggett, C. Agostoni, O. Goulet, O. Hernell, B. Koletzko, and H.L. Lafeber Antireflux or antiregurgitation milk products for infants and young children: a commentary by the ESPGHAN Committee on Nutrition J Pediatr Gastroenterol Nutr 34 2002 496 498
56. P.E. Putnam, S.R. Orenstein, H.B. Wessel, and R.M. Stowe Tardive dyskinesia associated with use of metoclopramide in a child J Pediatr 121 1992 983 985
57. J.E. Bines, J.E. Quinlan, S. Treves, R.E. Kleinman, and H.S. Winter Efficacy of domperidone in infants and children with gastroesophageal reflux Pediatr Gastroenterol Nutr 14 1992 400 405
58. R.N. Brogden, A.A. Carmine, R.C. Heel, T.M. Speight, and G.S. Avery Domperidone. A review of its pharmacological activity, pharmacokinetics and therapeutic efficacy in the symptomatic treatment of chronic dyspepsia and as an antiemetic Drugs 24 1982 360 400
59. D.S. Pritchard, N. Baber, and T. Stephenson Should domperidone be used for the treatment of gastro-oesophageal reflux in children? Systematic review of randomized controlled trials in children aged 1 month to 11 years old Br J Clin Pharmacol 59 2005 725 729
60. J.I. Curry, T.D. Lander, and M.D. Stringer Review article: erythromycin as a prokinetic agent in infants and children Aliment Pharmacol Ther 15 2001 595 603
61. M. Hauben, and G.W. Amsden The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental? Drug Saf 25 2002 929 942
62. W.O. Cooper, M.R. Griffin, P. Arbogast, G.B. Hickson, S. Gautam, and W.A. Ray Very early exposure to erythromycin and infantile hypertrophic pyloric stenosis Arch Pediatr Adolesc Med 156 2002 647 650
63. C. Augood, S. MacLennan, R. Gilbert, and S. Logan Cisapride treatment for gastro-oesophageal reflux in children Cochrane Database Syst Rev 4 2003 CD002300
64. J.R. Dalby-Payne, A.M. Morris, and J.C. Craig Meta-analysis of randomized controlled trials on the benefits and risks of using cisapride for the treatment of gastroesophageal reflux in children Gastroenterol Hepatol 18 2003 196 202
65. K. Adachi, M. Ono, A. Kawamura, M. Yuki, H. Fujishiro, and Y. Kinoshita Nizatidine and cisapride enhance salivary secretion in humans Aliment Pharmacol Ther 16 2002 297 301
66. G.F. Goldin, M. Marcinkiewicz, T. Zbroch, L.P. Bityutskiy, R.W. McCallum, and J. Sarosiek Esophagoprotective potential of cisapride. An additional benefit for gastroesophageal reflux disease Dig Dis Sci 42 1997 1362 1369
67. H.E. Tutar, A. Kansu, A.G. Kalayci, N. Girgin, S. Atalay, and A. Imamoglu Effects of cisapride on ventricular repolarization in children Acta Paediatr 89 2000 820 823
68. Y. Vandenplas, A. Benatar, F. Cools, A. Arana, B. Hegar, and B. Hauser Efficacy and tolerability of cisapride in children Paediatr Drugs 3 2001 559 573
69. S.P. Spielberg NASPGN and ESPGHAN on the use of cisapride J Pediatr Gastroenterol Nutr 31 2000 212 213
70. K.G. Mandel, B.P. Daggy, D.A. Brodie, and H.I. Jacoby Review article: alginate-raft formulations in the treatment of heartburn and acid reflux Aliment Pharmacol Ther 14 2000 669 690
71. R. Del Buono, T.G. Wenzl, G. Ball, S. Keady, and M. Thomson Effect of Gaviscon Infant on gastro-oesophageal reflux in infants assessed by combined intraluminal impedance/pH Arch Dis Child 90 2005 460 463
72. Salvatore S, Hauser B, Salvatoni A, Vandenplas Y. Oral ranitidine and duration gastric pH > 4.0 in infants with persisting reflux symptoms. Acta Paediatr [in press].
73. D.S. Cothran, S.M. Borowitz, J.L. Sutphen, S.M. Dudley, and L.G. Donowitz Alteration of normal gastric flora in neonates receiving ranitidine J Perinatol 17 1997 383 388
74. E. Hassall, D. Israel, R. Shepherd, M. Radke, A. Dalvag, and B. Skold Omeprazole for treatment of chronic erosive esophagitis in children: a multicenter study of efficacy, safety, tolerability and dose requirements J Petriatr 137 2000 800 807
75. C. Faure, L. Michaud, E.K. Shaghaghi, M. Popon, D. Turck, and J. Navarro Intravenous omeprazole in children: pharmacokinetics and effect on 24-hour intragastric pH J Pediatr Gastroenterol Nutr 33 2001 144 148
76. T. Andersson, E. Hassall, P. Lundborg, R. Shepherd, M. Radke, and M. Marcon Pharmocokinetics of orally administered omeprazole in children Am J Gastroenterol 95 2000 3101 3106
77. G.F. Nelis, A.H. Engelage, and G. Samson Does long-term inhibition of gastric acid secretion with omeprazole lead to small intestinal bacterial overgrowth? Neth J Med 45 1994 93 100
78. D.S. Pashankar, and D.M. Israel Gastric polyps and nodules in children receiving long-term omeprazole therapy J Pediatr Gastroenterol Nutr 35 2002 658 662