Java Web start based software for automated quantitative nuclear analysis of prostate cancer and benign prostate hyperplasia

BioMedical Engineering Online

Volumn 4, Issue , 2005, Pages

  Singh, Swaroop S ^a   Kim, Desok ^b   Mohler, James L ^a,c,d,e  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

^e UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; BENIGN PROSTATE HYPERPLASIA; PROSTATE CANCER;

COMPUTER SOFTWARE; IMAGE ANALYSIS; IMMUNOLOGY; JAVA PROGRAMMING LANGUAGE; PROTEINS; REGRESSION ANALYSIS; UROLOGY; WEBSITES;

PATHOLOGY;

ANDROGEN RECEPTOR; NUCLEAR PROTEIN; TUMOR MARKER;

AFRICAN AMERICAN; ARTICLE; AUTOMATION; CELL NUCLEUS; CLASSIFICATION; COMPUTER PROGRAM; CONSTANTS AND COEFFICIENTS; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; EUROPEAN AMERICAN; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMAGE PROCESSING; IMAGING SYSTEM; IMMUNOHISTOCHEMISTRY; LABORATORY; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PROSTATE CANCER; PROSTATE EPITHELIUM; PROSTATE HYPERTROPHY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RACE DIFFERENCE; STUDENT T TEST; ALGORITHM; ARTIFICIAL INTELLIGENCE; COMPUTER ASSISTED DIAGNOSIS; COMPUTER LANGUAGE; CONTROLLED CLINICAL TRIAL; METABOLISM; PATHOLOGY; PROCEDURES; PROSTATE TUMOR; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ALGORITHMS; ARTIFICIAL INTELLIGENCE; CELL NUCLEUS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; PROGRAMMING LANGUAGES; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOFTWARE; TUMOR MARKERS, BIOLOGICAL;

EID: 27744536503     PISSN: 1475925X     EISSN: 1475925X     Source Type: Journal    
DOI: 10.1186/1475-925X-4-31     Document Type: Article

References (37)

1. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, Feuer EJ, Thun MJ: Cancer Statistics. A Cancer J Clin 2005, 55(1):10-30.
2. Scott WW, Menon M, Walsh PC: Hormonal therapy of prostatic cancer. Cancer 1980, 45:1929-36.
3. Tsai MJ, O'Malley BW: Molecular Mechanisms of Action of Steroid/Thyroid Receptor Superfamily Members. An Rev Biochem 1994, 63:451-486.
4. Brolin J, Ekman P: Microassays for androgen and progesterone receptor quantitation as compared with standard saturation analyses in human prostatic tissues. Urol Res 1991, 19(6):333-6.
5. Li R, Wheeler T, Dai H, Frolov A, Thompson T, Ayala G: High level of androgen receptor is associated with aggressive clinico-pathologic features and decreased biochemical recurrence-free survival in prostate: cancer patients treated with radical prostatectomy. Am J Surg Pathol 2004, 28(7):928-34.
6. Miyamoto KK, McSherry SA, Dent GA, Sar M, Wilson EM, French FS, Sharief Y, Mohler JL: Immunohistochemistry of the androgen receptor in human benign and malignant prostate tissue. J Urol 1993, 149(5):1015-9.
7. Sadi MV, Barrack ER: Image analysis of androgen receptor immunostaining in metastatic prostate cancer. Heterogeneity as a predictor of response to hormonal therapy. Cancer 1993, 71(8):2574-80.
8. Prins GS, Sklarew RJ, Pertschuk LP: Image analysis of androgen receptor immunostaining in prostate cancer accurately predicts response to hormonal therapy. J Urol 1998, 159(3):641-9.
9. Tilley WD, Lim-Tio SS, Horsfall DJ, Aspinall JO, Marshall VR, Skinner JM: Detection of discrete androgen receptor epitopes in prostate cancer by immunostaining: measurement by color video image analysis. Cancer Res 1994, 54(15):4096-102.
10. Diamond DA, Berry SJ, Umbricht C, Jewett HJ, Coffey DS: Computerized image analysis of nuclear shape as a prognostic factor for prostatic cancer. Prostate 1982, 3(4):321-32.
11. Mohler JL, Partin AW, Epstein JI, Becker RL, Mikel UV, Sesterhenn IA, Mostofi FK, Gleason DF, Sharief Y, Coffey DS: Prediction of prognosis in untreated stage A2 prostatic carcinoma. Cancer 1992, 69(2):511-9.
12. Kim D, JD Charlton, Coggins JM, Mohler JL: Semiautomated nuclear shape analysis of prostatic carcinoma and benign prostatic hyperplasia. Anal Quant Cytol Histol 1994, 16(6):400-14.
13. Veltri RW, Partin AW, Miller MC: Quantitative nuclear grade (QNG): A new image analysis-based biomarker of clinically relevant nuclear structure alterations. J Cellular Biochemistry 2000, 35:151-157.
14. Mofidi R, Walsh R, Ridgway PF, Crotty T, McDermott EW, Keaveny TV, Duffy MJ, Hill AD, O'Higgins N: Objective measurement of breast cancer oestrogen receptor status through digital image analysis. Eur J Surg Oncol 2003, 29(1):20-4.
15. Nabi G, Seth A, Dinda AK, Gupta NP: Computer based receptogram approach: an objective way of assessing immunohistochemistry of androgen receptor staining and its correlation with hormonal response in metastatic carcinoma of prostate. J Clin Pathol 2004, 57(2):146-50.
16. Blatt RJ, Clark AN, Courtney J, Tully C, Tucker AL: Automated quantitative analysis of angiogenesis in the rat aorta model using Image-Pro Plus 4.1. Comp Meth Prog Biomed 2004, 75(1):75-9.
17. Cell Analysis Systems Inc: Cell analysis systems: Quantitative estrogen progesterone user's manual, Application Version 2.0, Catalog Number 201325-00, USA. Apr. 1, 1990.
18. Acis®. . Information available from: http://www.chromavision.com/ product/acis.htm.
19. Autocyte Pathology Workstation. . Information available from: http://www.tripathimaging.com/nonus_acquic_immuno.htm
20. Schnorrenberg F, Pattichis CS, Kyriacou KC, Schizas CN: Computer-aided detection of breast cancer nuclei. IEEE Trans. Info Tech Biomed 1997, 1(2):128-40.
21. Xu YH, Sattler GL, Edwards H, Pitot HC: Nuclear-labeling index analysis (NLIA), a software package used to perform accurate automation of cell nuclear-labeling index analysis on immunohistochemically stained rat liver samples. Comput Methods Programs Biomed 2000, 63(1):55-70.
22. Loukas CG, Wilson GD, Vojnovic B, Linney A: An image analysis-based approach for automated counting of cancer cell nuclei in tissue sections. Cytometry 2003, 55A(1):30-42.
23. Kim D, Gregory CW, Smith GJ, Mohler JL: Immunohistochemical quantitation of androgen receptor expression using color video image analysis. Cytometry 1999, 35(1):2-10.
24. Kim D, Gregory CW, French FS, Smith GJ, Mohler JL: Androgen receptor expression and cellular proliferation during transition from androgen-dependent to recurrent growth after castration in the CWR22 prostate cancer xenograft. Am J Pathol 2002, 160(1):219-26.
25. Gaston KE, Ford OH III, Singh SS, Gregory CW, Weyel DE, Smith GJ, Mohler JL: A novel method for the analysis of the androgen receptor. Curr Urol Rep 2002, 3(1):67-74.
26. Coggins JM: Image and Graphics Library, Object-Oriented (IGLOO) Manual. Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 1992.
27. Java Web Start Reference Manual available [http://java.sun.com/products/ javawebstart/developers.html]
28. UNC Prostate Cancer Research [http://www.med.unc.edu/lccc/iac/Protocols/ downloads.html]
29. Seber GAF: Multivariate Observations. John Wiley & Sons, Inc; 1984:287-297.
30. Sharma S: Applied Multivariate Techniques. John Wiley & Sons, Inc; 1996:338-340.
31. Otsu N: A threshold selection method from gray-level histograms. IEEE Trans Systems Man Cybernetics 1979, 9:62-66.
32. Gonzalez RC, Woods RE: Digital image processing. Reading, MA: Addison-Wesley 1992:229-37.
33. Gaston KE, Kim D, Singh SS, Ford OH III, Mohler JL: Racial differences in androgen receptor protein expression in men with clinically localized prostate cancer. J Urol 2003, 170(3):990-3.
34. Olapade-Olaopa EO, Muronda CA, MacKay EH, Danso AP, Sandhu DP, Terry TR, Habib FK: Androgen receptor protein expression in prostatic tissues in Black and Caucasian men. Prostate 2004, 59(4):460-8.
35. Singh SS, Qaqish B, Johnson JL, Ford OH III, Foley JF, Maygarden SJ, Mohler JL: Sampling Strategy for Prostate Tissue Microarray for Ki-67 and Androgen Receptor Biomarkers. Anal Quant Cytol Histol 2004, 26(4):192-200.
36. Ford OH III, Singh SS, Miller SC, Smitherman AB, Lasater M, Mohler JL: Dual labeling of bromodeoxyuridine and other antigens of interest in archival formalin-fixed, paraffin-embedded tissue for computer assisted image analysis. in press.
37. Krzanwski WJ: Discrimination and classification of both binary and continuous variables. J Am Stat Assoc 1975, 70:782-790.