Cholestasis induced by model organic anions protects from acetaminophen hepatotoxicity in male CD-1 mice

Toxicology Letters

Volumn 160, Issue 3, 2006, Pages 204-211

  Silva, Vanessa M ^a   Hennig, Gayle E ^a   Manautou, José E ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Acetaminophen; Biliary disposition; Hepatotoxicity; Organic anions

Indexed keywords

AMARANTH; BROMOCRESOL GREEN; CARBON TETRACHLORIDE; DIBROMOSULFOPHTHALEIN; DYE; GLUTATHIONE; INDOCYANINE GREEN; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER; PARACETAMOL; ROSE BENGAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTASIS; CONTROLLED STUDY; DISEASE SEVERITY; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SAFETY;

ACETAMINOPHEN; AMARANTH DYE; ANIMALS; BILE DUCTS; CARBON TETRACHLORIDE; CHOLESTASIS; HEPATITIS, ANIMAL; HEPATITIS, TOXIC; INDOCYANINE GREEN; LIVER; MALE; MICE; MICE, INBRED STRAINS; ROSE BENGAL; SULFOBROMOPHTHALEIN;

AMARANTHUS CAUDATUS; ANIMALIA;

EID: 27744534069     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2005.07.004     Document Type: Article

References (26)

1. C. Acevedo, L. Bengochea, D.M. Tchercansky, G. Ouvina, J.C. Perazzo, N. Lago, A. Lemberg, and M.C. Rubio Cholestasis as a liver protective factor in paracetamol acute overdose Gen. Pharmacol. 26 1995 1619 1624
2. A. Allameh Role of glutathione conjugation in protection of weanling rat liver against acetaminophen-induced hepatotoxicity Mech. Ageing Dev. 95 1997 71 79
3. T. Amimoto Acetaminophen-induced hepatic injury in mice: the role of lipid peroxidation and effects of pretreatment with coenzyme Q10 and alpha-tocopherol Free Radic. Biol. Med. 19 1995 169 176
4. J.B. Bartolone, W.P. Beierschmitt, R.B. Birge, S.G. Hart, S. Wyand, S.D. Cohen, and E.A. Khairallah Selective acetaminophen metabolite binding to hepatic and extrahepatic proteins: an in vivo and in vitro analysis Toxicol. Appl. Pharmacol. 99 1989 240 249
5. W.P. Beierschmitt, J.T. Brady, J.B. Bartolone, D.S. Wyand, E.A. Khairallah, and S.D. Cohen Selective protein arylation and the age dependency of acetaminophen hepatotoxicity in mice Toxicol. Appl. Pharmacol. 98 1989 517 529
6. J.A. Castro, and G.D. Castro Carbon tetrachloride I.G. Sipes C.A. Mc Queen A.J. Gandolfi Comprehensive Toxicology 1997 Elsevier Oxford 251 271
7. C. Chen, G.E. Hennig, D.J. McCann, and J.E. Manautou Effects of clofibrate and indocyanine green on the hepatobiliary disposition of acetaminophen and its metabolites in male CD-1 mice Xenobiotica 30 2000 1019 1032
8. G.L. Ellman Tissue sulfhydryl groups Arch. Biochem. Biophys. 82 1959 70 77
9. J.L. Farber, and R.J. Gerson Mechanisms of cell injury with hepatotoxic chemicals Pharmacol. Rev. 36 1984 71S 75S
10. U. Gerlach, and W. Hiby Sorbitol dehydrogenase H.U. Bergmeyer Methods in Enzymatic Analysis 1974 Verlag Chemie Weinheim 742 775
11. Z. Gregus, and C.D. Klaassen Comparison of biliary excretion of organic anions in mice and rats Toxicol. Appl. Pharmacol. 63 1982 13 20
12. A.W. Harman The effectiveness of antioxidants in reducing paracetamol-induced damage subsequent to paracetamol activation Res. Commun. Chem. Pathol. Pharmacol. 49 1985 215 228
13. T. Kamisako, Y. Kobayashi, K. Takeuchi, T. Ishihara, K. Higuchi, Y. Tanaka, E.C. Gabazza, and Y. Adachi Recent advances in bilirubin metabolism research: the molecular mechanism of hepatocyte bilirubin transport and its clinical relevance J. Gastroenterol. 35 2000 659 664
14. J.E. Manautou, V.M. Silva, G.E. Hennig, and H.E. Whiteley Repeated dosing with the peroxisome proliferator clofibrate decreases the toxicity of model hepatotoxic agents in male mice Toxicology 172 1998 1 10
15. J.E. Manautou, S.G. Emeigh Hart, E.A. Khairallah, and S.D. Cohen Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: effects on selective protein arylation and glutathione depletion Fundam. Appl. Toxicol. 29 1996 229 237
16. J.E. Manautou, D.J. Hoivik, A. Tveit, S.G. Hart, E.A. Khairallah, and S.D. Cohen Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity Toxicol. Appl. Pharmacol. 129 1994 252 263
17. J.E. Manautou, and C. Chen Collection of bile and urine samples for determining the urinary and hepatobiliary disposition of xenobiotics in mice Current Protocols in Toxicology 2004 John Wiley and Sons Suppl. 22, 5.7.1
18. D.K. Meijer, R.J. Vonk, K. Keulemans, and J.G. Weitering Hepatic uptake and biliary excretion of dibromosulphthalein. Albumin dependence, influence of phenobarbital and nafenopin pretreatment and the role of y and z protein J. Pharmacol. Exp. Ther. 202 1977 8 21
19. L.C. Mireles, M.A. Lum, and P.A. Dennery Antioxidant and cytotoxic effects of bilirubin on neonatal erythrocytes Pediatr. Res. 45 1999 355 362
20. K.A. Nguyen, J.M. Carbone, V.M. Silva, C. Chen, G.E. Hennig, H.E. Whiteley, and J.E. Manautou The PPAR activator docosahexaenoic acid prevents acetaminophen hepatotoxicity in male CD-1 mice J. Toxicol. Environ. Health A 58 1999 171 186
21. P. Ott Hepatic elimination of indocyanine green with special reference to distribution kinetics and the influence of plasma protein binding Pharmacol. Toxicol. 82 1998 1 48
22. D.A. Page, and G.P. Carlson The role of the intestinal tract in the elimination of carbon tetrachloride Toxicol. Appl. Pharmacol. 124 1994 268 274
23. M.G. Roma, F.A. Crocenzi, and E.A. Rodriguez Garay Does paracellular permeability play a role in cholephilic dye-induced cholestasis? Toxicol. Lett. 84 1996 13 22
24. V.M. Silva, C. Chen, G.E. Hennig, H.E. Whiteley, and J.E. Manautou Changes in susceptibility to acetaminophen-induced liver injury by the organic anion indocyanine green Food Chem. Toxicol. 39 2001 271 278
25. S. Tazuma, H. Tokumo, G. Yamashita, K. Horikawa, H. Miura, N. Hirano, N. Aihara, M. Sasaki, K. Teramen, and H. Ochi Reversibility of organic anion-induced cholestasis: association with compensatory hypersecretion of biliary phospholipid and protein in the dog J. Gastroenterol. Hepatol. 9 1994 35 39
26. M. Trauner, and J.L. Boyer Bile salt transporters: molecular characterization, function, and regulation Physiol. Rev. 83 2003 633 671