Salmonella typhimurium grown in iron-rich media, inactivated with ferric chloride and adjuvanted with homologous bacterial DNA is potent and efficacious vaccine in mice

Vaccine

Volumn 23, Issue 48-49, 2005, Pages 5590-5598

  Kumar, Devender ^a,b   Singh, Ajit ^a  

^a CCS HARYANA AGRICULTURAL UNIVERSITY   (India)

^b INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Homologous bacterial DNA adjuvant; Iron inactivated vaccine; Salmonella typhimurium

Indexed keywords

BACTERIAL DNA; FERRIC CHLORIDE; IMMUNOGLOBULIN G; IRON; SALMONELLOSIS VACCINE;

ANIMAL EXPERIMENT; ANOREXIA; ANTIBODY PRODUCTION; ARTICLE; BACTERIAL GROWTH; BODY WEIGHT; CONTROLLED STUDY; DEPRESSION; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; DRUG SYNTHESIS; HUMORAL IMMUNITY; LETHAL DOSE; MENTAL DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; SKIN DISEASE; STATISTICAL SIGNIFICANCE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; CULTURE MEDIA; DNA, BACTERIAL; FERRIC COMPOUNDS; IRON; LETHAL DOSE 50; MICE; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; SALMONELLA VACCINES; VACCINATION;

EID: 27744493814     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.06.032     Document Type: Article

References (29)

1. T.K. Eisenstein, and B.M. Sultzer Immunity to Salmonella infection Adv Exp Med Biol 162 1983 261 296
2. R.M. Tsolis, R.A. Kingsley, S.M. Townsend, T.A. Ficht, L.G. Adams, and A.J. Baumler Of mice, calves and men: comparison of mouse typhoid model with other Salmonella infections Adv Exp Med Biol 473 1999 261 274
3. L.V. Reed, and H. Muench A simple method for estimating fifty percent end points Am J Hyg 27 1938 493 498
4. P.W. Jones, P. Collins, and M.M. Aitken Passive protection of calves against experimental infection with Salmonella typhimurium Vet Rec 123 1988 536 541
5. J. Sambrook, E.F. Fritsch, and T Maniatis 2nd ed. Molecular cloning: a laboratory manual vol.1 1989 Cold Spring Harbour Laboratory N.Y. p. 1.31
6. S.R. Maloy, V.J. Stewart, and R.K. Taylor The genetic analysis of pathogenic bacteria: a laboratory manual 1996 Cold Spring Harbor Laboratory Press New York p. 408-10
7. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature (London) 227 1970 680 685
8. P.J. Hitchcock, and T.M. Brown Morphological heterogeneity among Salmonella chemotypes in silver stained polyacrylamide gels J Bacteriol 154 1983 269 277
9. O. Westphal, and K. Jann Bacterial lipopolysaccharides: extraction with phenol-water and applications of the procedure Meth Carbohydr Chem 5 1965 83 91
10. M. Dubois, K.A. Gilles, J.K. Hamilton, P.A. Roberts, and F. Smith Colorimetric method for determination of sugar and related substances Anal Chem 28 1956 350 356
11. E. Neter, E.A. Gorzynski, R.M. Gino, O. Westphal, and O. Luderitz The enterobacterial hemagglutination test and its diagnostic potentialities Can J Microbiol 2 1956 232 244
12. O.H. Lowry, N.J. Rosenbrough, A.L. Farr, and A.J. Randall Protein measurement with the folin phenol reagent J Biol Chem 193 1951 265 272
13. B. Law, M.D. Malone, and R.A. Biddlecombe Enzyme-linked immunosorbent assay (ELISA) development and optimization B. Law Immunoassay: a practical guide 1996 Taylor and Francis London 127 147
14. B. Halliwell, and J.M.C. Gutteridge Free radicals in biology 1991 Clarendon Oxford
15. S.C. Andrews, A.K. Robinson, and F. Rodriguez-Quinones Bacterial iron homeostasis FEMS Microbiol Rev 27 2003 215 237
16. V. Braun Avoidance of iron toxicity through regulation of bacterial iron transport Biol Chem 378 1997 779 786
17. V. Braun, and H. Killmann Bacterial solutions to the iron-supply problem Trends Biochem Sci 24 1999 104 109
18. M.M.S.M. Wosten, L.F.F. Kox, S. Chamnogpol, F.C. Soncini, and E.A. Groisman A signal transduction system that responds to extracellular iron Cell 103 2000 113 125
19. J. Bjarnason, C.M. Southward, and M.G. Surette Genomic profiling of iron-responsive genes in Salmonella enterica serovar typhimurium by high-throughput screening of a random promoter library J Bacteriol 185 2003 4973 4982
20. J.F. Ernst, R.L. Bennett, and L.I. Rothfield Constitutive expression of the iron-enterochelin and ferrichrome uptake systems in a mutant strain of Salmonella typhimurium J Bacteriol 135 1978 928 934
21. J.W. Foster, and J.K. Hall Effect of Salmonella typhimurium ferric uptake regulator (fur) mutation on iron-and pH-regulated protein synthesis J Bacteriol 174 1992 4317 4323
22. A.J. Baumler, J.G. Kusters, I. Stojiljkovic, and F. Heffron Salmonella typhimurium loci involved in survival within macrophages Infect Immun 62 1994 1623 1630
23. P. Rishi, C.L. Woodward, W.K. Kim, and S.C. Ricke Salmonella enterica serovar Typhimurium hilA-lacZY fusion gene response to iron chelation or supplementation in rich and minimal media J Environ Sci Health B 39 2004 861 870
24. J. Warren, M. Kende, and K.K. Takano The adjuvant effect of powdered ferric oxide: enhancement of response to Mycoplasma pneumoniae and respiratory syncytial virus vaccines J Immuol 102 1969 1300 1308
25. H.L. Davies Use of CpG DNA for enhancing immune responses Curr Top Microbiol Immunol 247 2000 171 182
26. R.S. Chu, T. Mc Cool, N.S. Greenspan, J.R. Schreiber, and C.V. Harding CpG oligodeoxynucleotides act as adjuvants for pneumooccocal polysaccaride-protein conjugate vaccine and enhance anti-polysaccharide immunoglobulin G2a (IgG2a) and IgG3 antibodies Infect Immun 68 2000 1450 1456
27. A.M. Krieg Immune effects and mechanisms of action of CpG motifs Vaccine 19 2001 618 622
28. K.L. Elkins, T.R. Rhinehart-Jones, S. Stibitz, J.S. Conover, and D.M. Klansman Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria J Immunol 162 1999 2291 2298
29. 1-based immunity Cell Immunol 198 1999 69 75