Atypical IgA/IgG pemphigus involving the skin, oral mucosa, and colon in a child: A novel variant of IgA pemphigus?

Pediatric Dermatology

Volumn 22, Issue 4, 2005, Pages 321-327

  Bruckner, Anna L ^a   Fitzpatrick, James E ^b   Hashimoto, Takashi ^c   Weston, William L ^b   Morelli, Joseph G ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; CEFALEXIN; DAPSONE; DESMOGLEIN 3; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; PARACETAMOL; PREDNISONE;

ANAMNESIS; ARTICLE; AUTOIMMUNE DISEASE; BLISTER; CASE REPORT; CLINICAL FEATURE; COLON INJURY; COMPUTER ASSISTED TOMOGRAPHY; CONJUNCTIVITIS; DIARRHEA; DIFFERENTIAL DIAGNOSIS; DOSE RESPONSE; FEVER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MOUTH LESION; PEMPHIGUS; PRIORITY JOURNAL; PUSTULE; SCHOOL CHILD; SKIN DEFECT; STEVENS JOHNSON SYNDROME;

ANTI-INFLAMMATORY AGENTS; ANTIBODIES; AUTOANTIGENS; BASEMENT MEMBRANE; CHILD; COLONIC DISEASES; DAPSONE; DESMOGLEIN 3; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPIDERMIS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MALE; MOUTH DISEASES; MOUTH MUCOSA; PEMPHIGUS; PREDNISONE;

EID: 27744475083     PISSN: 07368046     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1525-1470.2005.22408.x     Document Type: Article

References (27)

1. Anhalt GJ, Kim S, Stanley JR, et al. Paraneoplastic pemphigus: an autoimmune mucocutaneous disease associated with neoplasia. N Engl J Med 1990;323:1729-1735.
2. Ishii K, Amagai M, Hall RP, et al. Characterization of autoantibodies in pemphigus using antigen-specific enzyme-liked immunosorbent assays with baculovirus-expressed recombinant desmogleins. J Immunol 1997;159:2010-2017.
3. Hasimoto T, Komai A, Futei Y, et al. Detection of IgA autoantibodies to desmogliens by an enzyme-linked immunosorbent assay. Arch Dermatol 2001;137:735-738.
4. Hashimoto T, Kiyokawa C, Mori O, et al. Human desmocollin 1 (Dsc 1) is an autoantigen for the subcomeal pustular dermatosis type of IgA pemphigus. J Invest Dermatol 1997;109:127-131.
5. Nie Z, Nagata Y, Joubeh S, et al. IgA antibodies of linear IgA bullous dermatosis recognize the 15th collagenous domain of BP 180. J Invest Dermatol 2000;115:1164-1166.
6. Rabinowitz LG, Esterly NB. Inflammatory bullous diseases in children. Dermatol Clin 1993;11:565-581.
7. Weston WL, Morelli JG, Huff JC. Misdiagnosis, treatments, and outcomes in the immunobullous diseases in children. Pediatr Dermatol 1997;14:264-272.
8. Bjarnason B, Flosadottir E. Childhood, neonatal and stillborn pemphigus vulgaris. Int J Dermatol 1999;38:680-688.
9. Robinson ND, Hashimoto T, Amagai M, et al. The new pemphigus variants. J Am Acad Dermatol 1999;40:649-671.
10. Nishikawa T, Hashimoto T. Dermatoses with intraepidermal IgA deposits. Clin Dermatol 2000;18:315-318.
11. Hashimoto T. Immunopathology of IgA pemphigus. Clin Dermatol 2001;19:683-689.
12. Karpati S, Amagai M, Liu WL, et al. Identification of desmoglein 1 as autoantigen in a patient with intraepidermal neutrophilic IgA dermatosis type of IgA pemphigus. Exp Dermatol 2000;9:224-228.
13. Prost C, Intrator L, Wechsler J, et al. IgA autoantibodies bind to pemphigus vulgaris antigen in a case of intraepidermal neutrophilic IgA dermatosis. J Am Acad Dermatol 1991;25:846-848.
14. Wang J, Kwon J, Ding X, et al. Nonsecretory IgA1 autoantibodies targeting desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis. Am J Pathol 1997;150:1901-1907.
15. Amagai M. Autoimmunity against desmosomal cadherins in pemphigus. J Dermatol Sci 1999;20:92-102.
16. Huff JC, Golitz LE, Kunke KS. Intraepidermal neutrophilic IgA dermatosis. N Engl J Med 1985;313:1643-1645.
17. Saurat J-H, Merot Y, Salomon D, et al. Pemphigus-like IgA deposits and vesiculo-pustular dermatosis in a 10-year-old girl. Dermatologica 1987;175:96-100.
18. Caputo R, Pistritto G, Gianni E, et al. IgA pemphigus in a child. J Am Acad Dermatol 1991;25:383-386.
19. Teraki Y, Amagi N, Hashimoto T, et al. Intercellular IgA dermatosis of childhood. Arch Dermatol 1991;127:221-224.
20. Weston WL, Friednash M, Hashimoto T, et al. A novel childhood pemphigus vegetans variant of intraepidermal neutrophilic IgA dermatosis. J Am Acad Dermatol 1998;38:635-638.
21. Gooptu C, Mendelsohn S, Amagai M, et al. Unique immunobullous disease in a child with a predominantly IgA response to three desmosomal proteins. Br J Dermatol 1999;141:882-886.
22. Amagai M, Klaus-Kovtun V, Stanley JR. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell 1991;67:869-877.
23. Stone DD. Rectal lesions and toxic dilatation of the colon in a case of pemphigus vulgaris. Dig Dis 1971;16:163-166.
24. Schwermann M, Lechner W, Elsner C, et al. Pemphigus vulgaris mit beteiligung von duodenum und colon. Z Haut Geschlechtskr 1987;63:101-104.
25. Koch PJ, Goldschmidt MD, Walsh MJ, et al. Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene. Eur J Cell Biol 1991;55:200-208.
26. Chan LS, Vanderlugt CJ, Hashimoto T, et al. Epitope spreading: lessons from autoimmune skin diseases. J Invest Dermatol 1998;110:103-109.
27. Iwatsuki K, Han G-W, Fukuti R, et al. Internalization of constitutive desmogleins with the subsequent induction of desmoglein 2 in pemphigus lesions. Br J Dermatol 1999;140:35-43.