In vitro and in vivo evaluation of guar gum matrix tablets for oral controlled release of water-soluble diltiazem hydrochloride

AAPS PharmSciTech

Volumn 6, Issue 1, 2005, Pages

  Al Saidan, Saleh M ^a   Krishnaiah, Yellela S R ^a   Patro, Srinivas S ^b   Satyanaryana, Vemulapalli ^c  

^a KUWAIT UNIVERSITY   (Kuwait)

^b ANDHRA UNIVERSITY   (India)

^c Sipra Labs Pvt Ltd   (India)

Author keywords

Diltiazem hydrochloride; Guar gum; In vitro drug release; In vivo evaluation; Matrix tablets; Oral controlled release

Indexed keywords

DILTIAZEM; GUAR GUM; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; STARCH;

ADULT; ARTICLE; BODY FLUID; COLON; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DIFFUSION; DRUG GRANULATION; DRUG MARKETING; DRUG RELEASE; DRUG SOLUBILITY; DRUG STORAGE; GASTROINTESTINAL TRACT; HUMAN; HUMAN EXPERIMENT; HUMIDITY; IN VITRO STUDY; IN VIVO STUDY; MALE; NORMAL HUMAN; PHYSICAL PARAMETERS; SIMULATION; SUSTAINED RELEASE PREPARATION; TABLET MATRIX; VISCOSITY; VOLUNTEER;

ADMINISTRATION, ORAL; ADULT; ANIMALS; BODY FLUIDS; CROSS-OVER STUDIES; DELAYED-ACTION PREPARATIONS; DILTIAZEM; DRUG EVALUATION; GALACTANS; HUMANS; MALE; MANNANS; PLANT GUMS; RATS; SOLUBILITY; TABLETS, ENTERIC-COATED; WATER;

EID: 27744473846     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060105     Document Type: Article

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