Apparent pKa shifts of titratable residues at high denaturant concentration and the impact on protein stability

Biophysical Chemistry

Volumn 118, Issue 2-3, 2005, Pages 88-92

  Marti, Daniel N ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

1H NMR; Guanidine hydrochloride; pKa values; Protein folding; Protein stability; Urea

Indexed keywords

ASPARTIC ACID; GLUTAMINE; GUANIDINE; HISTIDINE; LYSINE; UREA; GLUTAMIC ACID; PROTEIN;

ARTICLE; CONCENTRATION (PARAMETERS); NUCLEAR MAGNETIC RESONANCE; PKA; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; CHEMISTRY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PHYSICAL CHEMISTRY; SENSITIVITY AND SPECIFICITY; TITRIMETRY;

ASPARTIC ACID; CHEMISTRY, PHYSICAL; GLUTAMIC ACID; GUANIDINE; HISTIDINE; HYDROGEN-ION CONCENTRATION; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN FOLDING; PROTEINS; SENSITIVITY AND SPECIFICITY; TITRIMETRY; UREA;

EID: 27744471390     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2005.06.011     Document Type: Article

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