Habitual physical activity in children: The role of genes and the environment

American Journal of Clinical Nutrition

Volumn 82, Issue 4, 2005, Pages 901-908

  Franks, Paul W ^a   Ravussin, Eric ^b   Hanson, Robert L ^a   Harper, Inge T ^a   Allison, David B ^c   Knowler, William C ^a   Tataranni, P Antonio ^a   Salbe, Arline D ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Children; Doubly labeled water; Genetics; Physical activity energy expenditure; Physical activity level; Twins

Indexed keywords

ARTICLE; BODY WEIGHT; DEMOGRAPHY; DIZYGOTIC TWINS; DOUBLY LABELED WATER TECHNIQUE; ENERGY EXPENDITURE; ENVIRONMENTAL FACTOR; FEMALE; GENE; HUMAN; HUMAN EXPERIMENT; LUNG GAS EXCHANGE; MALE; MEDICAL RESEARCH; METABOLIC RATE; MONOZYGOTIC TWINS; PHENOTYPE; PHYSICAL ACTIVITY; PRESCHOOL CHILD; SCHOOL CHILD; BASAL METABOLIC RATE; BODY COMPOSITION; CHILD; ENERGY METABOLISM; ENVIRONMENT; EXERCISE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; LIFESTYLE; OXYGEN CONSUMPTION; PHYSIOLOGY; RADIODENSITOMETRY; TWINS;

DEUTERIUM; DIAGNOSTIC AGENT;

BASAL METABOLISM; BODY COMPOSITION; BODY WEIGHT; CHILD; CHILD, PRESCHOOL; DENSITOMETRY, X-RAY; DEUTERIUM; ENERGY METABOLISM; ENVIRONMENT; EXERCISE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LIFE STYLE; MALE; OXYGEN CONSUMPTION; PHENOTYPE; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 27744469119     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/82.4.901     Document Type: Article

References (56)

1. US Department of Health & Human Services. Physical activity and health: a report of the Surgeon General. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, 1996.
2. Moran A, Jacobs DR Jr, Steinberger J, et al. Insulin resistance during puberty: results from clamp studies in 357 children. Diabetes 1999;48:2039-44.
3. Sinaico AR, Jacobs DR Jr, Steinberger J, et al. Insulin resistance syndrome in childhood: associations of the euglycemic insulin clamp and fasting insulin with fatness and other risk factors. J Pediatr 2001;139:700-7.
4. Sinaiko AR, Steinberger J, Moran A, et al. Relation of insulin resistance to blood pressure in childhood. J Hypertens 2002;20:509-17.
5. Steinberger J. Insulin resistance and cardiovascular risk in the pediatric patient. Prog Pediatr Cardiol 2001;12:169-75.
6. Bao W, Srinivasan SR, Wattigney WA, Berenson GS. Persistence of multiple cardiovascular risk clustering related to syndrome X from childhood to young adulthood. The Bogalusa Heart-Study. Arch Intern Med 1994;154:1842-7.
7. Fagot-Campagna A, Burrows NR, Williamson DF. The public health epidemiology of type 2 diabetes in children and adolescents: a case study of American Indian adolescents in the Southwestern United States. Clin Chim Acta 1999;286:81-95.
8. Fagot-Campagna A. Emergence of type 2 diabetes mellitus in children: epidemiological evidence. J Pediatr Endocrinol Metab 2000;13(suppl): 1395-1402.
9. Caspersen CJ, Pereira MA, Curran KM. Changes in physical activity patterns in the United States, by sex and cross-sectional age. Med Sci Sports Exerc 2000;32:1601-9.
10. Reilly JJ, Jackson DM, Montgomery C, et al. Total energy expenditure and physical activity in young Scottish children: mixed longitudinal study. Lancet 2004;363:211-2.
11. Pratt M, Macera CA, Blanton C. Levels of physical activity and inactivity in children and adults in the United States: current evidence and research issues. Med Sci Sports Exerc 1999;31(suppl):S526-33.
12. Telama R, Yang X, Laakso L, Viikari J. Physical activity in childhood and adolescence as predictor of physical activity in young adulthood. Am J Prev Med 1997;13:317-23.
13. Tammelin T, Nayha S, Hills AP, Jarvelin MR. Adolescent participation in sports and adult physical activity. Am J Prev Med 2003;24:22-8.
14. Bouchard C, Malina RM, Perusse L. Genetics of fitness and physical performance. Champaign, IL: Human Kinetics, 1997.
15. Simonen RL, Perusse L, Rankinen T, Rice T, Rao DC, Bouchard C. Familial aggregation of physical activity levels in the Québec Family Study. Med Sci Sports Exerc 2003;34:1137-42.
16. Perusse L, Leblanc C, Bouchard C. Familial resemblance in lifestyle components: results from the Canada Fitness Survey. Can J Public Health 1988;79:201-5.
17. Perusse L, Tremblay A, Leblanc C, Bouchard C. Genetic and environmental influences on level of habitual physical activity and exercise participation. Am J Epidemiol 1989;129:1012-22.
18. Boomsma DI, van den Bree MB, Orlebeke JF, Molenaar PC. Resemblances of parents and twins in sports participation and heart rate. Behav Genet 1989;19:123-41.
19. Kaprio J, Koskenvuo M, Sarna S. Cigarette smoking, use of alcohol, and leisure-time physical activity among same-sexed adult male twins. Prog Clin Biol Res 1981;69:37-46.
20. Sallis JF, Patterson TL, Buono MJ, Atkins CJ, Nader PR. Aggregation of physical activity habits in Mexican-American and Anglo families. J Behav Med 1988;11:31-41.
21. Koopmans JP, van Doornen LJP, Boomsma DI. Smoking and sports participation. In: Goldbourt U, de Faire U, Berg K, eds. Genetic factors in coronary heart disease. London, United Kingdom: Kluwer Academic Publishers, 1994:217-35.
22. Lauderdale DS, Fabsitz R, Meyer JM, Sholinsky P, Ramakrishnan V, Goldberg J. Familial determinants of moderate and intense physical activity: a twin study. Med Sci Sports Exerc 1997;29:1062-8.
23. Maia JA, Thomis M, Beunen G. Genetic factors in physical activity levels: a twin study. Am J Prev Med 2002;23(suppl):87-91.
24. Mitchell BD, Rainwater DL, Hsueh WC, Kennedy AJ, Stern MP, Maccluer JW. Familial aggregation of nutrient intake and physical activity: results from the San Antonio Family Heart Study. Ann Epidemiol. 2003;13:128-35.
25. Frederiksen H, Christensen K. The influence of genetic factors on physical functioning and exercise in second half of life. Scand J Med Sci Sports 2003;13:9-18.
26. Ooki S, Yamada K, Asaka A. Zygosity diagnosis of twins by questionnaire for twins' mothers. Acta Genet Med Gemellol 1993;42:17-22.
27. Fontvieille AM, Harper IT, Ferraro RT, Spraul M, Ravussin E. Daily energy expenditure by five-year-old children, measured by doubly-labeled water. J Pediatr 1993;123:200-7.
28. Ravussin E, Harper IT, Rising R, Bogardus C. Energy expenditure by doubly-labeled water: validation in lean and obese subjects. Am J Physiol 1991;261:E402-9.
29. Goran MI, Kaskoun MC, Carpenter WH, Poehlman ET, Ravussin E, Fontvieille AM. Estimating body composition of young children by using bioelectrical resistance. J Appl Physiol 1993;75:1776-80.
30. Mazess RB, Barden HS, Bisek JP, Hanson J. Dual energy X-ray absorptiometry for total body and regional bone mineral and soft tissue composition. Am J Clin Nutr 1990;55:950-4.
31. Fontvieille AM, Dwyer J, Ravussin E. Resting metabolic rate and body composition in Pima Indian and Caucasian children. Int. J Obes Relat Metab Disord 1992;16:535-42.
32. Schutz Y, Bessard T, Jequiér E. Diet-induced thermogenesis measured over a whole day in obese and nonobese women. Am J Clin Nutr 1984; 40:542-52.
33. Falconer DS. Introduction to quantitative genetics. 3rd ed. Edinburgh, Scotland: Oliver and Boyd, 1990.
34. Neale MC, Cardon LR. Methodology for genetic studies of twins and families. Boston, MA: Kluwer Academic Publishers, 1992.
35. Faith MS, Pietrobelli A, Nunez C, Heo M, Heymsfield SB, Allison DB. Evidence for independent genetic influences on fat mass and body mass index in a pediatric twin sample. Pediatrics 1999;104:61-7.
36. Allison DB, Heshka S, Neale MC, Tishler PV, Heymsfield SB. Genetic, environmental, and phenotypic links between body mass index and blood pressure among women. Am J Med Genet 1992;55:335-41.
37. Neale MC, Miller MB. The use of likelihood-based confidence intervals in genetic models. Behav Genet 1997;27:113-20.
38. Ekelund U, Yngve A, Brage S, Westerterp K, Sjostrom M. Body movement and physical activity energy expenditure in children and adolescents: how to adjust for differences in body size and age. Am J Clin Nutr 2004;79:851-6.
39. Echtay KS, Roussel D, St-Pierre J, et al. Superoxide activates mitochondrial uncoupling proteins. Nature 2002;415:96-9.
40. Ekelund U, Franks PW, Wareham NJ, Aman J. Oxygen uptakes adjusted for body composition in normal-weight and obese adolescents. Obes Res 2004;12:513-20.
41. Tataranni PA, Harper IT, Snitker S, et al. Body weight gain in free-living Pima Indians: effect of energy intake vs expenditure. Int J Obes Relat Metab Disord 2003;27:1578-83.
42. Ravussin E, Bogardus C. Energy balance and weight regulation: genetics versus environment. Br J Nutr 2000;83(suppl):S17-20.
43. Schoeller DA, Jefford G. Determinants of the energy costs of light activities: inferences for interpreting doubly-labeled water data. Int J Obes Relat Metab Disord 2002;26:97-101.
44. Kohl HW III, Fulton JE, Caspersen CJ. Assessment of physical activity among children and adolescents: a review and synthesis. Prev Med 2000;31:S54-76.
45. Baranowski T, Dworkin R, Cieslik C, Hooks P, Clearman D, Ray L. Reliability and validity of self report of aerobic activity: Family Health Project. Res Q 1984;55:309-17.
46. Saris WH: The assessment and evaluation of daily physical activity in children. A review. Acta Paediatr Scand Suppl 1985;318:37-48.
47. Bouchard C, Tremblay A, Despres JP, et al. The response to long-term overfeeding in identical twins. N Engl J Med 1990;24:1477-82.
48. Loos RJ, Rankinen T, Tremblay A, Perusse L, Chagnon Y, Bouchard C. Melanocortin-4 receptor gene and physical activity in the Quebec Family Study. Int J Obes Relat Metab Disord 2005;29:420-8.
49. Simonen RL, Rankinen T, Perusse L, et al. Dopamine D2 receptor gene polymorphism and physical activity in two family studies. Physiol Behav 2003;78:751-7.
50. Winnicki M, Accurso V, Hoffmann M, et al. Physical activity and angiotensin-converting enzyme gene polymorphism in mild hypertensives. Am J Med Genet 2004;125:38-44.
51. Lorentzon M, Lorentzon R, Lerner UH, Nordstrom P. Calcium sensing receptor gene polymorphism, circulating calcium concentrations and bone mineral density in healthy adolescent girls. Eur J Endocrinol 2001;144:257-61.
52. Salmen T, Heikkinen AM, Mahonen A, et al. Relation of aromatase gene polymorphism and hormone replacement therapy to serum estradiol levels, bone mineral density, and fracture risk in early postmenopausal women. Ann Med 2003;35:282-8.
53. Montoye HJ, Kemper HCG, Saris WHM, Washburn RA. Measuring physical activity and energy expenditure. Champaign, IL: Human Kinetics, 1996.
54. Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N Engl J Med 2003;20:1085-95.
55. Lichtman SW, Pisarska K, Berman ER, et al. Discrepancy between self-reported and actual caloric intake and exercise in obese subjects. N Engl-J Med 1992;327:1893-8.
56. Rose RJ, Viken J, Dick DM, Bates JE, Pulkkinen L, Kaprio J. It does take a village: nonfamilial environments and children's behavior. Psychol Sci 2003;14:273-7.