The impact of age and gender on biology, clinical features and treatment outcome of non-Hodgkin lymphoma in childhood and adolescence

British Journal of Haematology

Volumn 131, Issue 1, 2005, Pages 39-49

  Burkhardt, Birgit ^a   Zimmermann, Martin ^a   Oschlies, Ilske ^b   Niggli, Felix ^c   Mann, Georg ^d   Parwaresch, Reza ^b   Riehm, Hansjoerg ^e   Schrappe, Martin ^b   Reiter, Alfred ^a,f  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^d ST ANNA CHILDREN S HOSPITAL   (Austria)

^e HANNOVER MEDICAL SCHOOL   (Germany)

^f JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; METHOTREXATE; ANTINEOPLASTIC AGENT; ASPARAGINASE; BFM 86 PROTOCOL; BFM-86 PROTOCOL; MERCAPTOPURINE; PREDNISONE; VINCRISTINE;

ADOLESCENT; ADULT; ANAPLASTIC LARGE CELL LYMPHOMA; ARTICLE; B CELL LYMPHOMA; BIOLOGY; BURKITT LYMPHOMA; CHILD; CHILDHOOD; CLINICAL FEATURE; DRUG FATALITY; FEMALE; FOLLOW UP; GENDER; HUMAN; INFANT; LEUKEMIA; LYMPHOBLASTOMA; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; NEWBORN; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; SCHOOL CHILD; SURVIVAL; TREATMENT OUTCOME; AGE; CLINICAL TRIAL; DISEASE FREE SURVIVAL; MORTALITY; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; PATHOLOGY; PRESCHOOL CHILD; REGRESSION ANALYSIS; SEX DIFFERENCE; SURVIVAL RATE;

6-MERCAPTOPURINE; ADOLESCENT; AGE FACTORS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ASPARAGINASE; CHILD; CHILD, PRESCHOOL; CYCLOPHOSPHAMIDE; CYTARABINE; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; INFANT; LYMPHOMA, NON-HODGKIN; MALE; METHOTREXATE; MULTIVARIATE ANALYSIS; PREDNISONE; REGRESSION ANALYSIS; SEX FACTORS; SURVIVAL RATE; VINCRISTINE;

EID: 27744462595     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2005.05735.x     Document Type: Article

References (44)

1. Alizadeh A.A. Eisen M.B. Davis R.E. Ma C. Lossos I.S. Rosenwald A. Boldrick J.C. Sabet H. Tran T. Yu X. Powell J.I. Yang L. Marti G.E. Moore T. Hudson Jr, J. Lu L. Lewis D.B. Tibshirani R. Sherlock G. Chan W.C. Greiner T.C. Weisenburger D.D. Armitage J.O. Warnke R. Levy R. Wilson W. Grever M.R. Byrd J.C. Botstein D. Brown P.O. Staudt L.M. ( 2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature, 403, 503 511.
2. Atra A. Imeson J.D. Hobson R. Gerrard M. Hann I.M. Eden O.B. Carter R.L. Pinkerton C.R. ( 2000) Improved outcome in children with advanced stage B-cell non-Hodgkin's lymphoma (B-NHL): results of the United Kingdom Children Cancer Study Group (UKCCSG) 9002 protocol. British Journal of Cancer, 82, 1396 1402.
3. Beer S. Zetterberg A. Ihrie R.A. McTaggart R.A. Yang Q. Bradon N. Arvanitis C. Attardi L.D. Feng S. Ruebner B. Cardiff R.D. Felsher D.W. ( 2004) Developmental context determines latency of MYC-induced tumorigenesis. PLoS Biology, 2, e332.
4. Borkhardt A. Wuchter C. Viehmann S. Pils S. Teigler-Schlegel A. Stanulla M. Zimmermann M. Ludwig W.D. Janka-Schaub G. Schrappe M. Harbott J. ( 2002) Infant acute lymphoblastic leukemia - combined cytogenetic, immunophenotypical and molecular analysis of 77 cases. Leukemia, 16, 1685 1690.
5. Bowman W.P. Shuster J.J. Cook B. Griffin T. Behm F. Pullen J. Link M. Head D. Carroll A. Berard C. Murphy S. ( 1996) Improved survival for children with B-cell acute lymphoblastic leukemia and stage IV small noncleaved-cell lymphoma: a pediatric oncology group study. Journal of Clinical Oncology, 14, 1252 1261.
6. Brugieres L. Deley M.C. Pacquement H. Meguerian-Bedoyan Z. Terrier-Lacombe M.J. Robert A. Pondarre C. Leverger G. Devalck C. Rodary C. Delsol G. Hartmann O. ( 1998) CD30(+) anaplastic large-cell lymphoma in children: analysis of 82 patients enrolled in two consecutive studies of the French Society of Pediatric Oncology. Blood, 92, 3591 3598.
7. Cairo M.S. Krailo M.D. Morse M. Hutchinson R.J. Harris R.E. Kjeldsberg C.R. Kadin M.E. Radel E. Steinherz L.J. Morris E. Finlay J.L. Meadows A.T. ( 2002) Long-term follow-up of short intensive multiagent chemotherapy without high-dose methotrexate ('Orange') in children with advanced non-lymphoblastic non-Hodgkin lymphoma: a Children's Cancer Group Report. Leukemia, 16, 594 600.
8. Cairo M.S. Sposto R. Perkins S.L. Meadows A.T. Hoover-Regan M.L. Anderson J.R. Siegel S.E. Lones M.A. Tedeschi-Blok N. Kadin M.E. Kjeldsberg C.R. Wilson J.F. Sanger W. Morris E. Krailo M.D. Finlay J.L. ( 2003) Burkitt's and Burkitt-like lymphoma in children and adolescents: a review of the Children's Cancer Group experience. British Journal of Haematology, 120, 660 670.
9. Chessells J.M. Hall E. Prentice H.G. Durrant J. Bailey C.C. Richards S.M. ( 1998) The impact of age on outcome in lymphoblastic leukaemia; MRC UKALL X and XA compared: a report from the MRC Paediatric and Adult Working Parties. Leukemia, 12, 463 473.
10. Cox D.R. ( 1972) Regression models and life tables. Journal of the Royal Statistical Society, 34, 187 220.
11. Dave B.J. Weisenburger D.D. Higgins C.M. Pickering D.L. Hess M.M. Chan W.C. Sanger W.G. ( 2004) Cytogenetics and fluorescence in situ hybridization studies of diffuse large B-cell lymphoma in children and young adults. Cancer Genetics and Cytogenetics, 153, 115 121.
12. Eden O.B. Hann I. Imeson J. Cotterill S. Gerrard M. Pinkerton C.R. ( 1992) Treatment of advanced stage T cell lymphoblastic lymphoma: results of the United Kingdom Children's Cancer Study Group (UKCCSG) protocol 8503. British Journal of Haematology, 82, 310 316.
13. Frost M. Newell J. Lones M.A. Tripp S.R. Cairo M.S. Perkins S.L. ( 2004) Comparative immunohistochemical analysis of pediatric Burkitt lymphoma and diffuse large B-cell lymphoma. American Journal of Clinical Pathology, 121, 384 392.
14. Gray R.J. ( 1988) A class of K-sample tests for comparing the cumulative incidence of a competing risk. Annals of Statistics, 16, 1141 1154 Vardiman J. ( 2001) WHO Classification, Tumours of Haematopoietic and Lymphoid Tissue. IARC Press, Lyon.
15. Kaatsch P. Spix C. ( 2004) German Childhood Cancer Registry, Annual Report 2003. German Childhood Cancer Registry, Mainz, Germany.
16. Kalbfleisch J.D. Prentice R.L. ( 1980) The Statistical Analysis of Failure Time Data, pp. 163 188. John Wiley, New York, NY.
17. Kaplan E.L. Meier P. ( 1958) Non-parametric estimation from incomplete observations. Journal of the American Statistical Association, 53, 457 481.
18. Kuppers R. Klein U. Hansmann M.L. Rajewsky K. ( 1999) Cellular origin of human B-cell lymphomas. New England Journal of Medicine, 341, 1520 1529.
19. Le Deley M.C. Reiter A. Williams D. Rosolen A. Seidemann K. Pinkerton C. Patte C. Brugieres L. ( 1999) Prognostic factors in childhood anaplastic large cell lymphoma (ALCL), results of the European Intergroup Study (abstract). Annals of Oncology, 10 28.
20. Link M.P. Shuster J.J. Donaldson S.S. Berard C.W. Murphy S.B. ( 1997) Treatment of children and young adults with early-stage non-Hodgkin's lymphoma. New England Journal of Medicine, 337, 1259 1266.
21. Lister T.A. Crowther D. Sutcliffe S.B. Glatstein E. Canellos G.P. Young R.C. Rosenberg S.A. Coltman C.A. Tubiana M. ( 1989) Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease: Cotswolds meeting. Journal of Clinical Oncology, 7, 1630 1636.
22. Mantel E. ( 1966) Evaluation of survival data and tow new rank order statistics arising in its consideration. Cancer Chemotherapy Reports, 50, 163 170.
23. Marky I. Bjork O. Forestier E. Jonsson O.G. Perkkio M. Schmiegelow K. Storm-Mathiesen I. Gustafsson G. ( 2004) Intensive chemotherapy without radiotherapy gives more than 85% event-free survival for non-Hodgkin lymphoma without central nervous involvement: a 6-year population-based study from the nordic society of pediatric hematology and oncology. Journal of Pediatric Hematology/Oncology, 26, 555 560.
24. Murphy S.B. ( 1980) Classification, staging and end results of treatment of childhood non-Hodgkin lymphomas: dissimilarities from lymphomas in adults. Seminars in Oncology, 7, 332 339.
25. Natkunam Y. Lossos I.S. Taidi B. Zhao S. Lu X. Ding F. Hammer A.S. Marafioti T. Byrne Jr., G.E. Levy S. Warnke R.A. Levy R. ( 2005) Expression of the human germinal center-associated lymphoma (HGAL) protein, A new marker of germinal center B-cell derivation. Blood, 105, 3979 3986.
26. Oschlies I. Schirmacher J. Krams M. Zimmermann M. Reiter A. Parwaresch R. ( 2003) The immunophenotype and genotype of pediatric diffuse large B-cell lymphoma differs from that of adult B-cell lymphomas (abstract). Journal of Pediatric Hematology/Oncology, 25, S3.
27. Patte C. Kalifa C. Flamant F. Hartmann O. Brugieres L. Valteau-Couanet D. Bayle C. Caillaud J.M. Lemerle J. ( 1992) Results of the LMT81 protocol, a modified LSA2L2 protocol with high dose methotrexate, on 84 children with non-B-cell (lymphoblastic) lymphoma. Medical and Pediatric Oncology, 20, 105 113.
28. Patte C. Auperin A. Michon J. Behrendt H. Leverger G. Frappaz D. Lutz P. Coze C. Perel Y. Raphael M. Terrier-Lacombe M.J. ( 2001) The Societe Francaise d'Oncologie Pediatrique LMB89 protocol: highly effective multiagent chemotherapy tailored to the tumor burden and initial response in 561 unselected children with B-cell lymphomas and L3 leukemia. Blood, 97, 3370 3379.
29. Percy C.L. Smith M.A. Linet M. Lynn A. Ries L.A.G. Friedman D. ( 1999) Lymphomas and reticuloendothelial neoplasms. In: Cancer Incidence and Survival among Children and Adolescents: United States SEER Program 1975-1995 ( ed. by L.A.G. Ries M.A. Smith J.G. Gruney pp. 35 49. National Cancer Institute, SEER Program, Bethesda, MD.
30. Pillon M. Di Tullio M.T. Garaventa A. Cesaro S. Putti M.C. Favre C. Lippi A. Surico G. Di Cataldo A. D'Amore E. Zanesco L. Rosolen A. ( 2004) Long-term results of the first Italian Association of Pediatric Hematology and Oncology protocol for the treatment of pediatric B-cell non-Hodgkin lymphoma (AIEOP LNH92). Cancer, 101, 385 394.
31. Pui C.H. Boyett J.M. Relling M.V. Harrison P.L. Rivera G.K. Behm F.G. Sandlund J.T. Ribeiro R.C. Rubnitz J.E. Gajjar A. Evans W.E. ( 1999) Sex differences in prognosis for children with acute lymphoblastic leukemia. Journal of Clinical Oncology, 17, 818 824.
32. Pusill-Wachtsmuth B. Oschlies I. Zimmermann M. Ludwig W.-D. Parwaresch R. Mann G. Schrappe M. Riehm H. Reiter A. ( 2003) Prognostic factors in childhood T-cell lymphoblastic lymphoma treated in the three consecutive NHL-BFM studies (abstract). Pediatric Hematology/Oncology, 25, 4.
33. Ramakers-van Woerden N.L. Beverloo H.B. Veerman A.J. Camitta B.M. Loonen A.H. van Wering E.R. Slater R.M. Harbott J. Den Boer M.L. Ludwig W.D. Haas O.A. Janka-Schaub G.E. Pieters R. ( 2004) In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype. Leukemia, 18, 521 529.
34. Reiter A. Schrappe M. Tiemann M. Parwaresch R. Zimmermann M. Yakisan E. Dopfer R. Bucsky P. Mann G. Gadner H. Riehm H. ( 1994) Successful treatment strategy for Ki-1 anaplastic large-cell lymphoma of childhood: a prospective analysis of 62 patients enrolled in three consecutive Berlin-Frankfurt-Munster group studies. Journal of Clinical Oncology, 12, 899 908.
35. Reiter A. Schrappe M. Parwaresch R. Henze G. Muller-Weihrich S. Sauter S. Sykora K.W. Ludwig W.D. Gadner H. Riehm H. ( 1995) Non-Hodgkin's lymphomas of childhood and adolescence: results of a treatment stratified for biologic subtypes and stage-a report of the Berlin-Frankfurt-Munster Group. Journal of Clinical Oncology, 13, 359 372.
36. Reiter A. Schrappe M. Tiemann M. Ludwig W.D. Yakisan E. Zimmermann M. Mann G. Chott A. Ebell W. Klingebiel T. Graf N. Kremens B. Muller-Weihrich S. Pluss H.J. Zintl F. Henze G. Riehm H. ( 1999) Improved treatment results in childhood B-cell neoplasms with tailored intensification of therapy: a report of the Berlin-Frankfurt-Munster Group Trial NHL-BFM 90. Blood, 94, 3294 3306.
37. Reiter A. Schrappe M. Ludwig W.D. Tiemann M. Parwaresch R. Zimmermann M. Schirg E. Henze G. Schellong G. Gadner H. Riehm H. ( 2000) Intensive ALL-type therapy without local radiotherapy provides a 90% event-free survival for children with T-cell lymphoblastic lymphoma: a BFM group report. Blood, 95, 416 421.
38. Sandlund J.T. Downing J.R. Crist W.M. ( 1996) Non-Hodgkin's lymphoma in childhood. New England Journal of Medicine, 334, 1238 1248.
39. Sather H.N. ( 1986) Age at diagnosis in childhood acute lymphoblastic leukemia. Medical and Pediatric Oncology, 14, 166 172.
40. Sather H. Miller D. Nesbit M. Heyn R. Hammond D. ( 1981) Differences in prognosis for boys and girls with acute lymphoblastic leukaemia. Lancet, 1, 739 743.
41. Seidemann K. Tiemann M. Schrappe M. Yakisan E. Simonitsch I. Janka-Schaub G. Dorffel W. Zimmermann M. Mann G. Gadner H. Parwaresch R. Riehm H. Reiter A. ( 2001) Short-pulse B-non-Hodgkin lymphoma-type chemotherapy is efficacious treatment for pediatric anaplastic large cell lymphoma: a report of the Berlin-Frankfurt-Munster Group Trial NHL-BFM 90. Blood, 97, 3699 3706.
42. Stansfeld A.G. Diebold J. Noel H. Kapanci Y. Rilke F. Kelenyi G. Sundstrom C. Lennert K. van Unnik J.A. Mioduszewska O. Wright D.M. ( 1988) Updated Kiel classification for lymphomas. Lancet, 1, 292 293 Kersey J.H. ( 1995) Comparison of treatment regimens for pediatric lymphoblastic non-Hodgkin's lymphoma: a Childrens Cancer Group Study. Journal of Clinical Oncology, 13, 1368 1376.
43. Williams D.M. Hobson R. Imeson J. Gerrard M. McCarthy K. Pinkerton C.R. ( 2002) Anaplastic large cell lymphoma in childhood: analysis of 72 patients treated on the United Kingdom Children's Cancer Study Group chemotherapy regimens. British Journal of Haematology, 117, 812 820.
44. Woessmann W. Seidemann K. Mann G. Zimmermann M. Burkhardt B. Oschlies I. Ludwig W.D. Klingebiel T. Graf N. Gruhn B. Juergens H. Niggli F. Parwaresch R. Gadner H. Riehm H. Schrappe M. Reiter A. ( 2005) The impact of the methotrexate administration schedule and dose in the treatment of children and adolescents with B-cell neoplasms - a report of the BFM group study NHL-BFM95. Blood, 105, 948 958.