Possibility of rat liver fibrogenesis inhibited by bone marrow-derived mesenchymal stem cells: A 7-week observation on survival time of stem cells and activation of hepatic stellate cells in liver of recipients and a survival analysis

Chinese Journal of Clinical Rehabilitation

Volumn 9, Issue 22, 2005, Pages 52-55

  Zhao, Dong Chang ^a   Lei, Jun Xia ^a   Chen, Rui ^a   Zhang, Xiu Ming ^a   Xu, Rui Yun ^a   Li, Shu Nong ^a   Xiang, Peng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA ACTIN; BILIRUBIN; COLLAGEN; DIMETHYLNITROSAMINE; EOSIN; HEMATOXYLIN; HYALURONIC ACID; HYDROXYPROLINE; LAMININ; SODIUM CHLORIDE; TOSYLCHLORAMIDE SODIUM;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; BODY MASS; BREATH ANALYSIS; CELL ACTIVATION; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CHINA; COMPUTER PROGRAM; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DIET; DONOR; FECES ANALYSIS; FEMALE; FIBROGENESIS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEPATITIS; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIVER CELL; LIVER FIBROSIS; LIVER FUNCTION; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; RADIOIMMUNOASSAY; RANDOMIZATION; RAT; RECIPIENT; STELLATE CELL; STUDENT T TEST; SURVIVAL RATE; URINALYSIS; Y CHROMOSOME;

EID: 27744458224     PISSN: 16715926     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Lee DS, Gil WH, Lee HH, et al. Factors affecting graft survival after living donor liver transplantation. Transplant Proc 2004;36(8):2255-6
2. Javazon EH, Beggs KJ, Flake AW. Mesenchymal stem cells: paradoxes of passaging. Exp Hematol 2004;32(5):414-25
3. Chinese source. 2005,9(7):63-5
4. Chinese source. 2004,8(28):6060-2
5. Chinese source. 2004,19(3):289-94
6. Ueki T, Kaneda Y, Tsutsui H, et al. Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med 1999;5(2):226-30
7. George J, Rao KR, Stern R, et al. Dimethylnitrosamine-induced liver injury in rats: the early deposition of collagen. Toxicology 2001;156(2-3):129-38
8. Fang B, Shi M, Liao L, et al. Systemic infusion of FLK1(+) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice. Transplantation 2004;78(1):83-8
9. Sakaida I, Terai S, Yamamoto N, et al. Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice. Hepatology 2004;40(6):1304-11
10. Bataller R, Brenner DA. Liver fibrosis. J Clin Invest 2005;115(2):209-18
11. Kanazawa Y, Verma IM. Little evidence of bone marrow-derived hepatocytes in the replacement of injured liver. Proc Natl Acad Sci U S A 2003;100 Suppl 1: 11850-3
12. Shackel N, Rockey D. In pursuit of the "Holy Grail"-stem cells, hepatic injury, fibrogenesis and repair. Hepatology 2005;41(1):16-8