Inhibition of interferon-γ signaling by a mercurio-substituted dihydropsoralen in murine keratinocytes

Biochemical Pharmacology

Volumn 70, Issue 12, 2005, Pages 1726-1734

  Martey, Christine A ^a   Vetrano, Anna M ^b   Whittemore, Marilyn S ^c   Mariano, Thomas M ^b   Heck, Diane E ^d   Laskin, Debra L ^d   Heindel, Ned D ^a   Laskin, Jeffrey D ^b  

^a LEHIGH UNIVERSITY   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c Buckman Laboratories Inc   (United States)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

Interferon ; Nitric oxide; Psoriasis; PUVA; Skin

Indexed keywords

BUTHIONINE SULFOXIMINE; GAMMA INTERFERON; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; IODOMERCURIO 4',5' DIHYDROTRIMETHYLPSORALEN; LUCIFERASE; NITRIC OXIDE; PHOTOSENSITIZING AGENT; PSORALEN DERIVATIVE; STAT1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOSYNTHESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA BINDING; DRUG BINDING SITE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GEL MOBILITY SHIFT ASSAY; GENE CONSTRUCT; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; IC 50; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPORTER GENE; SIGNAL TRANSDUCTION; ULTRAVIOLET A RADIATION;

ANIMALS; CELLS, CULTURED; INTERFERON TYPE II; KERATINOCYTES; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; ORGANOMERCURY COMPOUNDS; PSORALENS; PUVA THERAPY; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP-1; TRIOXSALEN;

EID: 27744443733     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.10.001     Document Type: Article

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