Study on the virulence, cell-mediated immune response and histolesivity of three field PRRSV strains with an ORF 5 genetic variation

Veterinary Research Communications

Volumn 29, Issue SUPPL. 2, 2005, Pages 241-243

  Corradi, Attilio ^a   Ferrari, M ^b   Cantoni, A M ^a   Robotti, C ^b   Alborali, L ^b   Di Lecce, R ^d   Candotti, P ^b   Sandri, G P ^c   Borghetti, P ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA LOMBARDIA E DELL EMILIA ROMAGNA   (Italy)

^c Veronesi Group   (Italy)

^d NONE

Author keywords

Cell mediated immune response; Histolesivity; ORF5; PRRSV; Virulence

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTERIVIRUS; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE SEQUENCE; GENETIC VARIABILITY; HISTOPATHOLOGY; INTERSTITIAL PNEUMONIA; LEUKOCYTE; LYMPHOCYTOPENIA; NONHUMAN; OPEN READING FRAME; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; SWINE DISEASE; THYMUS DISEASE; VIRUS DETECTION; VIRUS GENOME; VIRUS INFECTION; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; FLOW CYTOMETRY; IMMUNOPHENOTYPING; LUNG; LYMPH NODES; OPEN READING FRAMES; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SWINE; TONSIL; VARIATION (GENETICS); VIREMIA; VIRULENCE;

ANIMALIA; ARTERIVIRUS; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS; SUS SCROFA;

EID: 27744438098     PISSN: 01657380     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11259-005-0052-y     Document Type: Article

References (7)

1. Bignotti, E., Ferrari, M., Nicoloso, L., Faccini, S., Ajmone-Marsan, P., Nigrelli, A. and Moratti, R., 2002. Tipizzazione molecolare di virus della PRRS isolati in campo. Atti SIPAS, 28, 161-166
2. Ferrari, M. Tosini, A., Corradi, A., Borghetti, P., Scalvini, A., Cantoni, A.M., Ferrando, L. and Alborali, L., 2003. Experimental infection with a Porcine Reproductuive and Respiratory Syndrome Virus (PRRSV) strain with relevant genomic mutations in the ORF 5 region. In: Proceedings of 4th International Symposium on Emerging and Re-Emerging Pig Diseases. Rome, 43-44
3. Horter, D.C., Pogranichniy, R.M., Chang, C.C., Evans, R.B., Yoon, K.J. and Zimmerman, J.J., 2002. Characterization of the carrier state in porcine reproductive and respiratory syndrome virus infection. Veterinary Microbiology, 86, 213-228 10.1016/S0378-1135(02)00013-5
4. Oleksiewicz, M.B., Botner, A., Madsen, K.G. and Storgaard, T., 1998. Sensitive detection and typing of porcine reproductive and respiratory syndrome virus by RT-PCR amplification of whole viral genes. Veterinary Microbiology, 64, 7-22 10.1016/S0378-1135(98)00254-5
5. Scalvini, A., Nicoloso, L., Bignotti, E., Chegdani, F., Ajmone-Marsan, P. and Faccini, S., 2002. Variabilit̀ genetica del gene ORF 5 del virus della PRRS isolato da diversi focolai di infezione. Atti SISVET, 56, 177-178
6. Wensvoort, G., Terpstra, C., Pol, J.M.A., Laak, E.A.-ter, Bloemraad, M., Kluyver, E.P.-de, Kragten, C., Buiten, L.-van, Besten, A. den, Wagenaar, F., Broekhuijsen, J.M., Moonen, P.L.J.M., Zetstra, T., Boer, E.A.-de, Tibben, H.J., Jong, M.F.-de, Veld, P-van't, Groenland, G.J.R., Gennep, J.A.-van, Voets, M.T., Verheijden, J.H.M., Braamskamp, J., Ter Laak, E.A., De Kluyver, E.P., Van Buiten, L., Den Besten, A., De Boer, E.A., De Jong, M.F., Van't Veld, P. and Van Gennep, J.A., 1991. Mystery swine disease in the Netherlands: The isolation of Lelystad virus. Veterinary Quarterly, 13, 121-130 1835211
7. Yuan, S., Nelsen, C.J., Murtaugh, M.P., Schmitt, B.J. and Faaberg, K.S., 1999. Recombination between North American strains of porcine reproductive and respiratory syndrome virus. Virus Research, 6, 187-198